MG1655
W3110
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Gene Report : ilvN
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
     Deletion OCL06 (D)  ,  LD3-12-1 (LD)  
Related gene (W3110 PEC)
     Gene Search Search MG1655 PEC by gene name:  ilvN
Related strains
     Strains Search Search strains by gene name:  ilvN   Search strains by all related name:  ilvN b3670 ECK3661 f96 JW3645

General information  (Go to Linear View:)
 Gene Name ilvN  
 Alternative name b3670,ECK3661,f96,JW3645  
 Location, Length 3,848,825 - 3,849,115 (  -  ) ;   82.95 min ; 291 (bp) ,   96 (aa) Go to Linear View
 Product acetolactate synthase I, small subunit  
 Operon Name ivbL-ilvBN-uhpABC  
 Note acetolactate synthase I, valine sensitive, small subunit  
 Function enzyme; Amino acid biosynthesis: Isoleucine, Valine  
 Gene Ontology GO:0003984 ; acetolactate synthase activity ( ilvN )
GO:0008152 ; metabolic process ( ilvN )
GO:0008652 ; amino acid biosynthetic process ( ilvN )
GO:0009082 ; branched chain family amino acid biosynthetic process ( ilvN )
GO:0016597 ; amino acid binding ( ilvN )
GO:0016740 ; transferase activity ( ilvN )
 PID 1790103  
 EC number
  (KEGG Pathway)
 
2.2.1.6  
SWISS-PROT  ( Show details )
  botton Entry name(Acc.no) ILVN_ECOLI ( P08143 )
    -  Protein name Acetolactate synthase isozyme I small subunit  
    -  Synonyms EC 2.2.1.6, AHAS-I, Acetohydroxy-acid synthase I small subunit, ALS-I  
    -  Gene name Name=ilvN; OrderedLocusNames=b3670, c4595, z5164, ECs4611;  

 Linear View (Whole Mode)
View Location
   3840.0  –  3865.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP ilvN (  homologous genes of other bacterias  )  
    PDB     (database updated : 2007.02.20 )
         PSI-BLAST Chain A, Crystal Structure Of Acetolactate Synthase- Small Subunit From Thermotoga Maritima  
    SWISS-PROT     (database updated : 2007.02.20 )
         BLAST Acetolactate synthase isozyme I small subunit (AHAS-I) (Acetohydroxy-acid synthase I small subunit) (ALS-I)  
         PSI-BLAST Acetolactate synthase small subunit
    nr     (database updated : 2007.02.20 )
         BLAST acetolactate synthase small subunit [Escherichia coli O157:H7 EDL933]  
Pfam 28.0   (database updated : 2015-05 )
    Pfam
PROSITE
    PROSITE ASN_GLYCOSYLATION    PKC_PHOSPHO_SITE    CK2_PHOSPHO_SITE     

Other Cross-Reference
    COG COG0440E 
    EcoCyc ilvN 

MMBR References
Proc Natl Acad Sci U S A. 1982;79:6156-6160
Nucleotide sequence of the ilvB promoter-regulatory region: a biosynthetic operon controlled by attenuation and cyclic AMP.
Friden, P., T. Newman, and M. Freundlich.
Nucleic Acids Res. 1985;13:3995-4010
The nucleotide sequence of the ilvBN operon of Escherichia coli: sequence homologies of the acetohydroxy acid synthase isozyme.
Wek, R. C., C. A. Hauser, and G. W. Hatfield.
J Bacteriol. 1991;173(17):5258-9.
Locations of the lip, poxB, and ilvBN genes on the physical map of Escherichia coli.
Chang YY, Cronan JE Jr, Li SJ, Reed K, Vanden Boom T, Wang AY. ( 1832150 )

Sequences
Amino acid
FASTA format
0001 MQNTTHDNVI LELTVRNHPG VMTHVCGLFA RRAFNVEGIL CLPIQDSDKS HIWLLVNDDQ RLEQMISQID 
0071 KLEDVVKVQR NQSDPTMFNK IAVFFQ

Nucleotide
FASTA format

View sequence out neighbor 100bp
-100                                             tggcccggcg ctgatccatg tgcgcattga 
-070 tgccgaagaa aaagtttacc cgatggtgcc gccaggtgcg gcgaatactg aaatggtggg ggaataagcc 
0001 atgcaaaaca caactcatga caacgtaatt ctggagctca ccgttcgcaa ccatccgggc gtaatgaccc 
0071 acgtttgtgg cctttttgcc cgccgcgctt ttaacgttga aggcattctt tgtctgccga ttcaggacag 
0141 cgacaaaagc catatctggc tactggtcaa tgacgaccag cgtctggagc agatgataag ccaaatcgat 
0211 aagctggaag atgtcgtgaa agtgcagcgt aatcagtccg atccgacgat gtttaacaag atcgcggtgt 
0281 tttttcagta accgctcaag gcttgaacaa catcgcgctt atcgttaagg taagcgcgta ttttttttac 
0351 ccgccaggac aagaccatga tcaccgttgc ccttatagac g