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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
|
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
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Deletion
|
OCL06
(D)
,
LD3-12-1
(LD)
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|
Related gene (W3110 PEC)
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Gene Search
|
Search MG1655 PEC by gene name:
uhpB
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Related strains
|
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Strains Search
|
Search strains by gene name:
uhpB
Search strains by all related name:
uhpB b3668 ECK3659 f501 JW3643
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General information (Go to Linear View: )
|
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Gene Name
|
uhpB
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Alternative name
|
b3668,ECK3659,f501,JW3643
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Location, Length
|
3,846,657 - 3,848,159
(
-
)
;
82.91
min
;
1503
(bp) ,
500
(aa)
|
|
Product
|
sensory histidine kinase in two-component regulatory sytem with UhpA
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Operon Name
|
ivbL-ilvBN-uhpABC
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Note
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sensor histidine protein kinase phosphorylates UhpA; GO_component: GO:0009274 - peptidoglycan-based cell wall; GO_component: GO:0019866 - organelle inner membrane; GO_process: GO:0016052 - carbohydrate catabolic process; GO_process: GO:0006464 - protein modification process
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Function
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enzyme; Transport of small molecules: Carbohydrates, organic acids, alcohols
|
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Gene Ontology
|
GO:0000155
;
two-component sensor activity ( uhpB )
GO:0000160
;
two-component signal transduction system (phosphorelay) ( uhpB )
GO:0004673
;
protein histidine kinase activity ( uhpB )
GO:0005351
;
sugar:hydrogen ion symporter activity ( uhpB )
GO:0005524
;
ATP binding ( uhpB )
GO:0005886
;
plasma membrane ( uhpB )
GO:0006810
;
transport ( uhpB )
GO:0008643
;
carbohydrate transport ( uhpB )
GO:0016020
;
membrane ( uhpB )
GO:0016021
;
integral to membrane ( uhpB )
GO:0016301
;
kinase activity ( uhpB )
GO:0016740
;
transferase activity ( uhpB )
GO:0018106
;
peptidyl-histidine phosphorylation ( uhpB )
GO:0046983
;
protein dimerization activity ( uhpB )
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PID
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87082311
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EC number
(KEGG Pathway)
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SWISS-PROT
(
Show details
[
2
more]
)
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Entry name(Acc.no)
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UHPB_ECOLI
(
P09835
;
P76729
)
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- Protein name
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Sensor protein uhpB
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- Synonyms
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EC 2.7.3.-
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- Gene name
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Name=uhpB; OrderedLocusNames=b3668;
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Homology Analysis
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BLAST
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Bacteria
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GTOP
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uhpB
(
homologous genes of other bacterias
)
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PDB
(database updated :
2007.02.20
)
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PSI-BLAST
|
Chain A, Crystal Structure Of The Atp Binding Domain Of Prrb From Mycobacterium Tuberculosis
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SWISS-PROT
(database updated :
2007.02.20
)
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BLAST
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Sensor protein uhpB
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PSI-BLAST
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Chaperone clpB
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nr
(database updated :
2007.02.20
)
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BLAST
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UhpB [Shigella boydii Sb227]
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Pfam 28.0
(database updated :
2015-05
)
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Pfam
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PROSITE
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PROSITE
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ASN_GLYCOSYLATION
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
MYRISTYL
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MMBR References
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J Bacteriol. 1987;169(8):3556-63.
Nucleotide sequence of the uhp region of Escherichia coli.
Friedrich MJ, Kadner RJ.
(
3301805
)
|
J Bacteriol. 1992;174:2754-2762
Structure and function of the uhp genes for the sugar phosphate transport system in Escherichia coli and Salmonella typhimurium.
Island, M. D., B. Y. Wei, and R. J. Kadner.
|
J Bacteriol. 1993;175:5028-5034
Interplay between the membrane-associated UhpB and UhpC regulatory proteins.
Island, M. D., and R. J. Kadner.
|
J Bacteriol. 1987;169(8):3546-55.
Identification of uhp polypeptides and evidence for their role in exogenous induction of the sugar phosphate transport system of Escherichia coli K-12.
Weston LA, Kadner RJ.
(
3038843
)
|
| Sequences |
Amino acid
FASTA format
|
0001 MKTLFSRLIT VIACFFIFSA AWFCLWSISL HLVERPDMAV LLFPFGLRLG LMLQCPRGYW PVLLGAEWLL
0071 IYWLTQAVGL THFPLLMIGS LLTLLPVALI SRYRHQRDWR TLLLQGAALT AAALLQSLPW LWHGKESWNA
0141 LLLTLTGGLT LAPICLVFWH YLANNTWLPL GPSLVSQPIN WRGRHLVWYL LLFVISLWLQ LGLPDELSRF
0211 TPFCLALPII ALAWHYGWQG ALIATLMNAI ALIASQTWRD HPVDLLLSLL VQSLTGLLLG AGIQRLRELN
0281 QSLQKELARN QHLAERLLET EESVRRDVAR ELHDDIGQTI TAIRTQAGIV QRLAADNASV KQSGQLIEQL
0351 SLGVYDAVRR LLGRLRPRQL DDLTLEQAIR SLMREMELEG RGIVSHLEWR IDESALSENQ RVTLFRVCQE
0421 GLNNIVKHAD ASAVTLQGWQ QDERLMLVIE DDGSGLPPGS GQQGFGLTGM RERVTALGGT LHISCLHGTR
0491 VSVSLPQRYV
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 tgtcaccgaa aacggtacac gtccatcgcg
-070 ccaatctgat ggaaaaactg ggcgtcagta acgacgtaga gctggcgcgc cgcatgtttg atggctggtg
0001 atgaagacgt tgttctcccg cttaattacc gttattgcct gcttttttat cttctctgcc gcatggtttt
0071 gcctgtggag tatcagcctg catctggttg agcgccctga tatggcggtg ctgttatttc cgtttggtct
0141 gcgtctgggg ctaatgctgc aatgcccgcg cggatactgg cccgtattgc tgggcgcgga gtggctgctg
0211 atttactggc taacgcaggc ggtcggttta acccattttc cgttattgat gatcggtagt ttactgacgt
0281 tactgcccgt agcgctgatc tcgcgctatc gccatcagcg tgactggcgc accttgctgt tacagggggc
0351 ggcgttaacg gcggcggcgt tgttgcagtc gctgccctgg ctttggcacg gcaaagagtc gtggaatgcg
0421 ctgttgctga ctttaactgg cggcctgacg ctggccccga tatgtctggt gttctggcac tatctcgcca
0491 ataacacctg gctgccgctc ggtccgtcac tggtttctca gccaatcaac tggcgcgggc gacatctggt
0561 ctggtacttg ctgctgtttg ttatcagtct ctggctccag ttgggattgc cggacgaact gtcgcgcttt
0631 acgccattct gtctggcgct gccgattatc gcgctggcct ggcactatgg ttggcaaggg gcgctgattg
0701 cgacgttgat gaacgccatc gcgctgatcg ccagtcaaac ctggcgcgat catccggtgg atttattgct
0771 ctcgctgctg gtgcaaagtc tgacagggtt gttgcttggc gctggcatcc agcggttgcg tgaacttaac
0841 cagtcgctgc aaaaggaact ggcgcgcaat cagcatctgg ctgaacggtt gctggaaacc gaagagagcg
0911 tgcgccgtga tgtggcgcgt gagctgcatg atgatatcgg tcagaccatc actgctattc gtactcaggc
0981 gggcattgtt cagcggctgg cggcagataa cgccagcgtg aagcagagcg ggcagctcat cgaacaacta
1051 tcgctgggcg tttacgacgc ggtgcgccgt ttgttgggtc ggttacgtcc gcgccagttg gatgatctca
1121 ccctggagca ggccatccgc tcactgatgc gggaaatgga gctggaaggg cgcggtattg tcagccatct
1191 cgaatggcga atcgatgaat cagcgttaag cgaaaaccag cgcgtgacgc tgtttcgtgt ctgccaggaa
1261 gggctgaaca acattgtgaa acatgctgat gccagcgcgg tcaccctgca aggctggcag caggatgaac
1331 ggttgatgct ggttattgaa gacgatggca gcggtttgcc gccgggttcc gggcaacaag gttttggcct
1401 caccggaatg cgcgagcgcg taacggcgct gggtggcaca ttacacattt cctgtctgca cggcacgcgt
1471 gtcagcgttt ctctacctca acgctatgtc taaggtttga tgatgttgcc gtttctgaaa gcgcctgccg
1541 atgcgccatt aatgactgat aaatatgaaa ttgatgcccg ctatcgctac tggcgtcggc ata
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