MG1655
W3110
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Gene Report : uhpC
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
     Deletion OCL06 (D)  ,  LD3-12-1 (LD)  
Related gene (W3110 PEC)
     Gene Search Search MG1655 PEC by gene name:  uhpC
Related strains
     Strains Search Search strains by gene name:  uhpC   Search strains by all related name:  uhpC b3667 ECK3658 f440 JW3642

General information  (Go to Linear View:)
 Gene Name uhpC  
 Alternative name b3667,ECK3658,f440,JW3642  
 Location, Length 3,845,328 - 3,846,647 (  -  ) ;   82.88 min ; 1320 (bp) ,   439 (aa) Go to Linear View
 Product membrane protein regulates uhpT expression  
 Operon Name ivbL-ilvBN-uhpABC  
 Note regulator of uhpT; GO_component: GO:0009274 - peptidoglycan-based cell wall; GO_component: GO:0019866 - organelle inner membrane; GO_process: GO:0016052 - carbohydrate catabolic process; GO_process: GO:0006350 - transcription  
 Function regulator; Transport of small molecules: Carbohydrates, organic acids, alcohols  
 Gene Ontology GO:0005215 ; transporter activity ( uhpC )
GO:0005351 ; sugar:hydrogen ion symporter activity ( uhpC )
GO:0005886 ; plasma membrane ( uhpC )
GO:0006810 ; transport ( uhpC )
GO:0008643 ; carbohydrate transport ( uhpC )
GO:0016020 ; membrane ( uhpC )
GO:0016021 ; integral to membrane ( uhpC )
 PID 87082310  
 EC number
  (KEGG Pathway)
 
 
SWISS-PROT  ( Show details [ 2 more] )
  botton Entry name(Acc.no) UHPC_ECOLI ( P09836 ; P76728 )
    -  Protein name Regulatory protein uhpC.  
    -  Synonyms  
    -  Gene name Name=uhpC; OrderedLocusNames=b3667;  

 Linear View (Whole Mode)
View Location
   3835.0  –  3860.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP uhpC (  homologous genes of other bacterias  )  
    PDB     (database updated : 2007.02.20 )
         PSI-BLAST Chain A, Crystal Structure Of The Glycerol-3-Phosphate Transporter From E.Coli  
    SWISS-PROT     (database updated : 2007.02.20 )
         BLAST Regulatory protein uhpC  
         PSI-BLAST High-affinity glucose transporter SNF3
    nr     (database updated : 2007.02.20 )
         BLAST membrane protein regulates uhpT expression [Escherichia coli W3110]  
Pfam 28.0   (database updated : 2015-05 )
    Pfam
PROSITE
    PROSITE PKC_PHOSPHO_SITE    CK2_PHOSPHO_SITE    TYR_PHOSPHO_SITE    MYRISTYL    GLPT     

Other Cross-Reference
    COG COG2271G 
    EcoCyc uhpC 

MMBR References
J Bacteriol. 1987;169(8):3556-63.
Nucleotide sequence of the uhp region of Escherichia coli.
Friedrich MJ, Kadner RJ. ( 3301805 )
J Bacteriol. 1992;174:2754-2762
Structure and function of the uhp genes for the sugar phosphate transport system in Escherichia coli and Salmonella typhimurium.
Island, M. D., B. Y. Wei, and R. J. Kadner.
J Bacteriol. 1993;175:5028-5034
Interplay between the membrane-associated UhpB and UhpC regulatory proteins.
Island, M. D., and R. J. Kadner.
J Bacteriol. 1983;155(3):1052-61.
Genetic control of the hexose phosphate transport system of Escherichia coli: mapping of deletion and insertion mutations in the uhp region.
Kadner RJ, Shattuck-Eidens DM. ( 6309737 )
J Bacteriol. 1983;155(3):1062-70.
Molecular cloning of the uhp region and evidence for a positive activator for expression of the hexose phosphate transport system of Escherichia coli.
Shattuck-Eidens DM, Kadner RJ. ( 6350260 )
J Bacteriol. 1987;169(8):3546-55.
Identification of uhp polypeptides and evidence for their role in exogenous induction of the sugar phosphate transport system of Escherichia coli K-12.
Weston LA, Kadner RJ. ( 3038843 )

Sequences
Amino acid
FASTA format
0001 MLPFLKAPAD APLMTDKYEI DARYRYWRRH ILLTIWLGYA LFYFTRKSFN AAVPEILANG VLSRSDIGLL 
0071 ATLFYITYGV SKFVSGIVSD RSNARYFMGI GLIATGIINI LFGFSTSLWA FAVLWVLNAF FQGWGSPVCA 
0141 RLLTAWYSRT ERGGWWALWN TAHNVGGALI PIVMAAAALH YGWRAGMMIA GCMAIVVGIF LCWRLRDRPQ 
0211 ALGLPAVGEW RHDALEIAQQ QEGAGLTRKE ILTKYVLLNP YIWLLSFCYV LVYVVRAAIN DWGNLYMSET 
0281 LGVDLVTANT AVTMFELGGF IGALVAGWGS DKLFNGNRGP MNLIFAAGIL LSVGSLWLMP FASYVMQATC 
0351 FFTIGFFVFG PQMLIGMAAA ECSHKEAAGA ATGFVGLFAY LGASLAGWPL AKVLDTWHWS GFFVVISIAA 
0421 GISALLLLPF LNAQTPREA

Nucleotide
FASTA format

View sequence out neighbor 100bp
-100                                             cgagcgcgta acggcgctgg gtggcacatt 
-070 acacatttcc tgtctgcacg gcacgcgtgt cagcgtttct ctacctcaac gctatgtcta aggtttgatg 
0001 atgttgccgt ttctgaaagc gcctgccgat gcgccattaa tgactgataa atatgaaatt gatgcccgct 
0071 atcgctactg gcgtcggcat attctgctga ccatctggct gggttacgcg ctgttttact tcacgcggaa 
0141 aagttttaac gccgccgtac cagaaatcct tgctaacggc gtgctcagcc gtagcgatat cggcctgtta 
0211 gcgaccctgt tttacattac ctatggcgtg tcgaagtttg tctccggcat tgtcagcgat cgctcaaatg 
0281 cccgttattt tatggggata gggcttatcg ccacgggcat tatcaacatt ctgtttggct tctcgacgtc 
0351 gctatgggcg tttgccgtgc tctgggtgct gaacgccttt ttccagggct ggggttcacc ggtgtgtgcg 
0421 cgtctgttaa cggcctggta ttcacgtacc gagcgcggcg gttggtgggc attatggaac acggcgcata 
0491 acgtcggcgg cgcactcatt cccattgtga tggcagcggc tgcgctgcat tacggctggc gtgccgggat 
0561 gatgattgct ggttgtatgg cgatagtcgt ggggattttt ctctgctggc ggctacgcga tcgcccgcag 
0631 gcgttaggtt taccggcggt cggtgaatgg cgacacgacg cgctggaaat tgctcaacaa caagaagggg 
0701 cagggttgac gcgtaaagag atcctcacca aatatgtgtt gctgaatccg tatatctggc tgctttcgtt 
0771 ttgctatgtg ctggtctatg tggtccgggc ggcgatcaac gactggggca atttgtatat gtccgagaca 
0841 ctgggcgtcg atctggtcac ggcgaatacg gcagtgacga tgtttgaact gggcggattt atcggtgcgc 
0911 tggtagccgg ttggggctcg gacaaattgt ttaacggcaa ccgagggccg atgaatttga ttttcgccgc 
0981 cggaattttg ctttcagtcg gctccctgtg gctgatgcca tttgccagct acgtgatgca ggcaacctgc 
1051 ttcttcacca ttggtttttt tgtctttggc ccacagatgt taatcggtat ggcggcggca gagtgttccc 
1121 acaaagaggc ggcaggggcg gcgacggggt ttgtcggctt gtttgcttat ctgggggcgt cgcttgctgg 
1191 ttggccgctg gcgaaagtac tcgatacctg gcactggagc ggattttttg tggttatctc tatcgccgcc 
1261 gggatttccg cactgctgtt actgcccttt ttgaacgccc agacaccgcg cgaagcgtga tgcatctcac 
1331 cttttcactt catatccggc aaaactaaga aattttccag gttttgcctg gacgctatct caggcctgat 
1401 ttgctgctga tttttacaat