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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
|
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
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|
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Deletion
|
OCL07
(D)
|
|
Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
trmH
|
|
Related strains
|
|
Strains Search
|
Search strains by gene name:
trmH
Search strains by all related name:
trmH b3651 ECK3641 JW3626 o229 spoU
|
General information (Go to Linear View: )
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Gene Name
|
trmH
|
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Alternative name
|
b3651,ECK3641,JW3626,o229,spoU
|
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Location, Length
|
3,822,538 - 3,823,227
(
+
)
;
82.39
min
;
690
(bp) ,
229
(aa)
|
|
Product
|
tRNA mG18-2'-O-methyltransferase, SAM-dependent
|
|
Operon Name
|
rpoZ-spoT-trmH-recG
|
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Note
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GO_process: GO:0009451 - RNA modification
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Function
|
enzyme; tRNA modification
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Gene Ontology
|
GO:0003723
;
RNA binding ( trmH )
GO:0005737
;
cytoplasm ( trmH )
GO:0006396
;
RNA processing ( trmH )
GO:0008033
;
tRNA processing ( trmH )
GO:0008168
;
methyltransferase activity ( trmH )
GO:0008173
;
RNA methyltransferase activity ( trmH )
GO:0009020
;
tRNA (guanosine-2'-O-)-methyltransferase activity ( trmH )
GO:0016740
;
transferase activity ( trmH )
|
|
PID
|
1790083
|
EC number
(KEGG Pathway)
|
|
|
SWISS-PROT
(
Show details
[
1
more]
)
|
Entry name(Acc.no)
|
TRMH_ECOLI
(
P19396
)
|
|
- Protein name
|
tRNA (Guanosine-2'-O-)-methyltransferase
|
|
- Synonyms
|
EC 2.1.1.34, tRNA [GM18] methyltransferase
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- Gene name
|
OrderedLocusNames=b3651, z5077, ECs4526, SF3691, S4078;
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MMBR References
|
Nucleic Acids Res. 1993;21(23):5519
SpoU protein of Escherichia coli belongs to a new family of putative rRNA methylases.
Koonin EV, Rudd KE.
(
8265370
)
|
Nucleic Acids Res. 1997;25:4093-4097
The spoU gene of Escherichia coli, the fourth gene of the spoT operon, is essential for tRNA (Gm18) 2'-O-methyltransferase activity.
Persson, B. C., G. Jager, and C. Gustafsson.
|
| Sequences |
Amino acid
FASTA format
|
0001 MNPTRYARIC EMLARRQPDL TVCMEQVHKP HNVSAIIRTA DAVGVHEVHA VWPGSRMRTM ASAAAGSNSW
0071 VQVKTHRTIG DAVAHLKGQG MQILATHLSD NAVDFREIDY TRPTCILMGQ EKTGITQEAL ALADQDIIIP
0141 MIGMVQSLNV SVASALILYE AQRQRQNAGM YLRENSMLPE AEQQRLLFEG GYPVLAKVAK RKGLPYPHVN
0211 QQGEIEADAD WWATMQAAG
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Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 TCTGACCGCT CGTGACCGTG TGCATCTGGC
-070 GAATATCATG CGCAAAATCC GCGTGATGCC AGACGTGATT AAAGTCACCC GAAACCGAAA TTAATGTTTT
0001 atgaacccaa cacgttatgc acgcatctgc gaaatgctcg ccaggcggca gcctgatctg accgtctgca
0071 tggagcaggt ccacaaacct cataacgttt ctgcgattat tcgtaccgca gatgccgttg gcgtacatga
0141 agttcacgcc gtctggcctg gtagccgcat gcgcaccatg gcttcggcag cggcgggtag taacagctgg
0211 gtacaggtga aaacacaccg caccattggc gatgccgtcg ctcatctcaa aggccagggc atgcagattc
0281 tggcaaccca tctttctgat aacgctgtcg atttccgcga aattgattac actcgcccga cctgcatttt
0351 gatgggacag gagaaaacgg gcatcacgca ggaagcattg gccctggcgg atcaggacat catcattccg
0421 atgatcggca tggtgcagtc gctgaatgtt tccgttgcct cagccctcat tctttacgaa gcccagcgtc
0491 agcggcaaaa tgcaggcatg tacctgcgtg aaaacagcat gttgccggaa gcagagcaac aacgcctgtt
0561 gtttgaaggc ggctatccgg tgctggcgaa agtcgcaaaa cgcaaaggcc tgccttatcc ccacgtcaat
0631 cagcaaggcg agatcgaagc tgatgccgac tggtgggcta ctatgcaggc tgcagggtaa GTGCCATGAA
0701 AGGTCGCCTG TTAGATGCTG TCCCACTCAG TTCCCTAACG GGCGTTGGCG CAGCACTTAG TAACAAACTG
0771 GCGAAAATCA ACCTGCATAC
|
