MG1655
W3110
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Gene Report : mtlR
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
     Deletion OCL09 (D)  ,  OCL09-2 (D)  ,  OCL09-9 (D)  
Related gene (W3110 PEC)
     Gene Search Search MG1655 PEC by gene name:  mtlR
Related strains
     Strains Search Search strains by gene name:  mtlR   Search strains by all related name:  mtlR b3601 ECK3590 JW3575 o195

General information  (Go to Linear View:)
 Gene Name mtlR  
 Alternative name b3601,ECK3590,JW3575,o195  
 Location, Length 3,773,595 - 3,774,182 (  +  ) ;   81.33 min ; 588 (bp) ,   195 (aa) Go to Linear View
 Product mannitol operon repressor  
 Operon Name mtlADR  
 Note repressor for mtl; GO_component: GO:0005737 - cytoplasm; GO_process: GO:0016052 - carbohydrate catabolic process; GO_process: GO:0006350 - transcription  
 Function regulator; Degradation of small molecules: Carbon compounds  
 Gene Ontology GO:0003677 ; DNA binding ( mtlR )
GO:0006350 ; transcription ( mtlR )
GO:0006355 ; regulation of transcription, DNA-dependent ( mtlR )
 PID 1790029  
 EC number
  (KEGG Pathway)   		 
SWISS-PROT  ( Show details [ 1 more] )
  botton Entry name(Acc.no) MTLR_ECOLI ( P36563 )
    -  Protein name Mannitol operon repressor  
    -  Synonyms Mannitol repressor protein  
    -  Gene name Name=mtlR; OrderedLocusNames=b3601, c4418;  

 Linear View (Whole Mode)
View Location
   3765.0  –  3790.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP mtlR (  homologous genes of other bacterias  )  
    PDB     (database updated : 2007.02.20 )
         PSI-BLAST Chain A, Structural Genomics, The Crystal Structure Of A Putative Transcriptional Regulator Yggd From Shigella Flexneri 2a Str. 2457t  
    SWISS-PROT     (database updated : 2007.02.20 )
         BLAST Mannitol operon repressor (Mannitol repressor protein)  
         PSI-BLAST Mannitol operon repressor (Mannitol repressor protein)
    nr     (database updated : 2007.02.20 )
         BLAST DNA-binding repressor [Escherichia coli K12]  
Pfam 28.0   (database updated : 2015-05 )
    Pfam
PROSITE
    PROSITE PKC_PHOSPHO_SITE    CK2_PHOSPHO_SITE    MYRISTYL     

Other Cross-Reference
    EcoCyc mtlR 

MMBR References
J Bacteriol. 1994;176:840-847
The mannitol repressor (MtlR) of Escherichia coli.
Figge, R. M., T. M. Ramseier, and M. H. Saier.

Sequences
Amino acid
FASTA format 
0001 MVDQAQDTLR PNNRLSDMQA TMEQTQAFEN RVLERLNAGK TVRSFLITAV ELLTEAVNLL VLQVFRKDDY 
0071 AVKYAVEPLL DGDGPLGDLS VRLKLIYGLG VINRQEYEDA ELLMALREEL NHDGNEYAFT DDEILGPFGE 
0141 LHCVAALPPP PQFEPADSSL YAMQIQRYQQ AVRSTMVLSL TELISKISLK KAFQK
Nucleotide
FASTA format

View sequence out neighbor 100bp 
-100                                             CTGACAAAGG TCCGCAGGCG GCGCTGGCAC 
-070 AGATTTCCGG TCTTGATGCC AACAGCGAGG TTGTATCCGA GGCGGTAACC GCTTATAAAG CAATGCAATA 
0001 atggtggacc aggcgcagga caccctgcgc ccgaataaca gattgtcaga tatgcaggca acaatggaac 
0071 aaacccaggc ctttgaaaac cgtgtgcttg agcgtctgaa tgctggcaaa accgtgcgaa gctttctgat 
0141 caccgccgtc gagctcctga ccgaggcggt aaatcttctg gtgcttcagg tattccgcaa agacgattac 
0211 gcggtgaagt atgctgtaga accgttactc gacggcgatg gtccgctggg cgatctttct gtgcgtttaa 
0281 aactcattta cgggttgggc gtcattaacc gccaggaata cgaagatgcg gaactgctga tggcattgcg 
0351 tgaagagcta aatcacgacg gcaacgagta cgcctttacc gacgacgaaa tccttggacc ctttggtgaa 
0421 ctgcactgcg tggcggcgtt accaccgccg ccacagtttg aaccagcaga ctccagtttg tatgcaatgc 
0491 aaattcagcg ctatcaacag gctgtgcgat caacaatggt cctttcactg actgagctga tttccaaaat 
0561 cagcttaaaa aaagcctttc aaaagtaaGC AACGTCTGCT TACTGCCCCT CTACCTGCTT CGGCCGATAA 
0631 AGCCGACGAT AATACTCCAG ACGTTGTAGA TATAACGGCA CGCTTTCATC GGGTATTC