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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
|
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
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|
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Deletion
|
2-2
(LD)
,
OCL09,11-1 (LD 2-2'_CRS)
(D)
,
OCL09,11-2 (LD 2-2'_P/O)
(D)
,
OCL10
(D)
,
OCL11
(D)
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|
Related gene (W3110 PEC)
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Gene Search
|
Search MG1655 PEC by gene name:
xylR
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Related strains
|
|
Strains Search
|
Search strains by gene name:
xylR
Search strains by all related name:
xylR b3569 ECK3558 JW3541 o392
|
General information (Go to Linear View: )
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Gene Name
|
xylR
|
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Alternative name
|
b3569,ECK3558,JW3541,o392
|
|
Location, Length
|
3,733,002 - 3,734,180
(
+
)
;
80.46
min
;
1179
(bp) ,
392
(aa)
|
|
Product
|
DNA-binding transcriptional activator, xylose-binding
|
|
Operon Name
|
xylFGHR
|
|
Note
|
putative regulator of xyl operon; GO_component: GO:0005737 - cytoplasm; GO_function: GO:0016563 - transcription activator activity; GO_function: GO:0016564 - transcription repressor activity; GO_process: GO:0016052 - carbohydrate catabolic process; GO_process: GO:0006350 - transcription
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|
Function
|
putative regulator; Degradation of small molecules: Carbon compounds
|
|
Gene Ontology
|
GO:0003677
;
DNA binding ( xylR )
GO:0003700
;
transcription factor activity ( xylR )
GO:0005622
;
intracellular ( xylR )
GO:0006350
;
transcription ( xylR )
GO:0006355
;
regulation of transcription, DNA-dependent ( xylR )
GO:0043565
;
sequence-specific DNA binding ( xylR )
GO:0045449
;
regulation of transcription ( xylR )
|
|
PID
|
1789993
|
EC number
(KEGG Pathway)
|
|
|
SWISS-PROT
(
Show details
)
|
Entry name(Acc.no)
|
XYLR_ECOLI
(
P37390
)
|
|
- Protein name
|
Xylose operon regulatory protein.
|
|
- Synonyms
|
|
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- Gene name
|
Name=xylR; OrderedLocusNames=b3569, c4389, z4994, ECs4452;
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Homology Analysis
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BLAST
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Bacteria
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GTOP
|
xylR
(
homologous genes of other bacterias
)
|
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PDB
(database updated :
2007.02.20
)
|
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PSI-BLAST
|
Chain A, Purine Repressor Mutant-Hypoxanthine-Purf Operator Complex
|
|
SWISS-PROT
(database updated :
2007.02.20
)
|
|
BLAST
|
Xylose operon regulatory protein
|
|
PSI-BLAST
|
Xylose operon regulatory protein
|
|
nr
(database updated :
2007.02.20
)
|
|
BLAST
|
putative regulator of xyl operon [Escherichia coli O157:H7 EDL933]
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Pfam 28.0
(database updated :
2015-05
)
|
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Pfam
|
|
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PROSITE
|
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PROSITE
|
CAMP_PHOSPHO_SITE
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
TYR_PHOSPHO_SITE
MYRISTYL
AMIDATION
HTH_ARAC_FAMILY_1
|
|
MMBR References
|
Can J Biochem. 1982;60(2):144-51.
A Col E1 hybrid plasmid containing Escherichia coli genes complementing d-xylose negative mutants of Escherichia coli and Salmonella typhimurium.
Maleszka R, Wang PY, Schneider H.
(
6282416
)
|
Mol Gen Genet. 1984;194(3):410-5.
Cloning and characterization of the xyl genes from Escherichia coli.
Rosenfeld SA, Stevis PE, Ho NW.
(
6330500
)
|
Nucleic Acids Res. 1994;22:2576-2586
Analysis of the Escherichia coli genome. V. DNA sequence of the region from 76.0 to 81.5 minutes.
Sofia, H. J., V. D. Burland, D. L. Daniels, G. Plunkett, and F. R. Blattner.
|
| Sequences |
Amino acid
FASTA format
|
0001 MFTKRHRITL LFNANKAYDR QVVEGVGEYL QASQSEWDIF IEEDFRARID KIKDWLGDGV IADFDDKQIE
0071 QALADVDVPI VGVGGSYHLA ESYPPVHYIA TDNYALVESA FLHLKEKGVN RFAFYGLPES SGKRWATERE
0141 YAFRQLVAEE KYRGVVYQGL ETAPENWQHA QNRLADWLQT LPPQTGIIAV TDARARHILQ VCEHLHIPVP
0211 EKLCVIGIDN EELTRYLSRV ALSSVAQGAR QMGYQAAKLL HRLLDKEEMP LQRILVPPVR VIERRSTDYR
0281 SLTDPAVIQA MHYIRNHACK GIKVDQVLDA VGISRSNLEK RFKEEVGETI HAMIHAEKLE KARSLLISTT
0351 LSINEISQMC GYPSLQYFYS VFKKAYDTTP KEYRDVNSEV ML
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 CCGCAACCAA ACGCCGTTCT TGATTTTGAT
-070 AAAAATTTTC TCAAAGCCGG TTACGTATTA CCGGTTTTGA GTTTTTGCAT GATTCAGCAG GAAAAGAACC
0001 atgtttacta aacgtcaccg catcacatta ctgttcaatg ccaataaagc ctatgaccgg caggtagtag
0071 aaggcgtagg ggaatattta caggcgtcac aatcggaatg ggatattttc attgaagaag atttccgcgc
0141 ccgcattgat aaaatcaagg actggttagg agatggcgtc attgccgact tcgacgacaa acagatcgag
0211 caagcgctgg ctgatgtcga cgtccccatt gttggggttg gcggctcgta tcaccttgca gaaagttacc
0281 cacccgttca ttacattgcc accgataact atgcgctggt tgaaagcgca tttttgcatt taaaagagaa
0351 aggcgttaac cgctttgctt tttatggtct tccggaatca agcggcaaac gttgggccac tgagcgcgaa
0421 tatgcatttc gtcagcttgt cgccgaagaa aagtatcgcg gagtggttta tcaggggtta gaaaccgcgc
0491 cagagaactg gcaacacgcg caaaatcggc tggcagactg gctacaaacg ctaccaccgc aaaccgggat
0561 tattgccgtt actgacgccc gagcgcggca tattctgcaa gtatgtgaac atctacatat tcccgtaccg
0631 gaaaaattat gcgtgattgg catcgataac gaagaactga cccgctatct gtcgcgtgtc gccctttctt
0701 cggtcgctca gggcgcgcgg caaatgggct atcaggcggc aaaactgttg catcgattat tagataaaga
0771 agaaatgccg ctacagcgaa ttttggtccc accagttcgc gtcattgaac ggcgctcaac agattatcgc
0841 tcgctgaccg atcccgccgt tattcaggcc atgcattaca ttcgtaatca cgcctgtaaa gggattaaag
0911 tggatcaggt actggatgcg gtcgggatct cgcgctccaa tcttgagaag cgttttaaag aagaggtggg
0981 tgaaaccatc catgccatga ttcatgccga gaagctggag aaagcgcgca gtctgctgat ttcaaccacc
1051 ttgtcgatca atgagatatc gcaaatgtgc ggttatccat cgctgcaata tttctactct gtttttaaaa
1121 aagcatatga cacgacgcca aaagagtatc gcgatgtaaa tagcgaggtc atgttgtagC GATGATGAGA
1191 ATTGTCGGCG TCACATCAGG TAACGCTGCG TGGTTGTCGG ATGCGGCGTG AACGCCTTAT CCGACCTACC
1261 CGCCAGGCAT GATAAAACG
|