MG1655
W3110
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Gene Report : xylR
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
     Deletion 2-2 (LD)  ,  OCL09,11-1 (LD 2-2'_CRS) (D)  ,  OCL09,11-2 (LD 2-2'_P/O) (D)  ,  OCL10 (D)  ,  OCL11 (D)  
Related gene (W3110 PEC)
     Gene Search Search MG1655 PEC by gene name:  xylR
Related strains
     Strains Search Search strains by gene name:  xylR   Search strains by all related name:  xylR b3569 ECK3558 JW3541 o392

General information  (Go to Linear View:)
 Gene Name xylR  
 Alternative name b3569,ECK3558,JW3541,o392  
 Location, Length 3,733,002 - 3,734,180 (  +  ) ;   80.46 min ; 1179 (bp) ,   392 (aa) Go to Linear View
 Product DNA-binding transcriptional activator, xylose-binding  
 Operon Name xylFGHR  
 Note putative regulator of xyl operon; GO_component: GO:0005737 - cytoplasm; GO_function: GO:0016563 - transcription activator activity; GO_function: GO:0016564 - transcription repressor activity; GO_process: GO:0016052 - carbohydrate catabolic process; GO_process: GO:0006350 - transcription  
 Function putative regulator; Degradation of small molecules: Carbon compounds  
 Gene Ontology GO:0003677 ; DNA binding ( xylR )
GO:0003700 ; transcription factor activity ( xylR )
GO:0005622 ; intracellular ( xylR )
GO:0006350 ; transcription ( xylR )
GO:0006355 ; regulation of transcription, DNA-dependent ( xylR )
GO:0043565 ; sequence-specific DNA binding ( xylR )
GO:0045449 ; regulation of transcription ( xylR )
 PID 1789993  
 EC number
  (KEGG Pathway)
 
 
SWISS-PROT  ( Show details )
  botton Entry name(Acc.no) XYLR_ECOLI ( P37390 )
    -  Protein name Xylose operon regulatory protein.  
    -  Synonyms  
    -  Gene name Name=xylR; OrderedLocusNames=b3569, c4389, z4994, ECs4452;  

 Linear View (Whole Mode)
View Location
   3720.0  –  3745.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP xylR (  homologous genes of other bacterias  )  
    PDB     (database updated : 2007.02.20 )
         PSI-BLAST Chain A, Purine Repressor Mutant-Hypoxanthine-Purf Operator Complex  
    SWISS-PROT     (database updated : 2007.02.20 )
         BLAST Xylose operon regulatory protein  
         PSI-BLAST Xylose operon regulatory protein
    nr     (database updated : 2007.02.20 )
         BLAST putative regulator of xyl operon [Escherichia coli O157:H7 EDL933]  
Pfam 28.0   (database updated : 2015-05 )
    Pfam
PROSITE
    PROSITE CAMP_PHOSPHO_SITE    PKC_PHOSPHO_SITE    CK2_PHOSPHO_SITE    TYR_PHOSPHO_SITE    MYRISTYL    AMIDATION    HTH_ARAC_FAMILY_1     

Other Cross-Reference
    COG COG1609K 
    EcoCyc xylR 

MMBR References
Can J Biochem. 1982;60(2):144-51.
A Col E1 hybrid plasmid containing Escherichia coli genes complementing d-xylose negative mutants of Escherichia coli and Salmonella typhimurium.
Maleszka R, Wang PY, Schneider H. ( 6282416 )
Mol Gen Genet. 1984;194(3):410-5.
Cloning and characterization of the xyl genes from Escherichia coli.
Rosenfeld SA, Stevis PE, Ho NW. ( 6330500 )
Nucleic Acids Res. 1994;22:2576-2586
Analysis of the Escherichia coli genome. V. DNA sequence of the region from 76.0 to 81.5 minutes.
Sofia, H. J., V. D. Burland, D. L. Daniels, G. Plunkett, and F. R. Blattner.

Sequences
Amino acid
FASTA format
0001 MFTKRHRITL LFNANKAYDR QVVEGVGEYL QASQSEWDIF IEEDFRARID KIKDWLGDGV IADFDDKQIE 
0071 QALADVDVPI VGVGGSYHLA ESYPPVHYIA TDNYALVESA FLHLKEKGVN RFAFYGLPES SGKRWATERE 
0141 YAFRQLVAEE KYRGVVYQGL ETAPENWQHA QNRLADWLQT LPPQTGIIAV TDARARHILQ VCEHLHIPVP 
0211 EKLCVIGIDN EELTRYLSRV ALSSVAQGAR QMGYQAAKLL HRLLDKEEMP LQRILVPPVR VIERRSTDYR 
0281 SLTDPAVIQA MHYIRNHACK GIKVDQVLDA VGISRSNLEK RFKEEVGETI HAMIHAEKLE KARSLLISTT 
0351 LSINEISQMC GYPSLQYFYS VFKKAYDTTP KEYRDVNSEV ML

Nucleotide
FASTA format

View sequence out neighbor 100bp
-100                                             CCGCAACCAA ACGCCGTTCT TGATTTTGAT 
-070 AAAAATTTTC TCAAAGCCGG TTACGTATTA CCGGTTTTGA GTTTTTGCAT GATTCAGCAG GAAAAGAACC 
0001 atgtttacta aacgtcaccg catcacatta ctgttcaatg ccaataaagc ctatgaccgg caggtagtag 
0071 aaggcgtagg ggaatattta caggcgtcac aatcggaatg ggatattttc attgaagaag atttccgcgc 
0141 ccgcattgat aaaatcaagg actggttagg agatggcgtc attgccgact tcgacgacaa acagatcgag 
0211 caagcgctgg ctgatgtcga cgtccccatt gttggggttg gcggctcgta tcaccttgca gaaagttacc 
0281 cacccgttca ttacattgcc accgataact atgcgctggt tgaaagcgca tttttgcatt taaaagagaa 
0351 aggcgttaac cgctttgctt tttatggtct tccggaatca agcggcaaac gttgggccac tgagcgcgaa 
0421 tatgcatttc gtcagcttgt cgccgaagaa aagtatcgcg gagtggttta tcaggggtta gaaaccgcgc 
0491 cagagaactg gcaacacgcg caaaatcggc tggcagactg gctacaaacg ctaccaccgc aaaccgggat 
0561 tattgccgtt actgacgccc gagcgcggca tattctgcaa gtatgtgaac atctacatat tcccgtaccg 
0631 gaaaaattat gcgtgattgg catcgataac gaagaactga cccgctatct gtcgcgtgtc gccctttctt 
0701 cggtcgctca gggcgcgcgg caaatgggct atcaggcggc aaaactgttg catcgattat tagataaaga 
0771 agaaatgccg ctacagcgaa ttttggtccc accagttcgc gtcattgaac ggcgctcaac agattatcgc 
0841 tcgctgaccg atcccgccgt tattcaggcc atgcattaca ttcgtaatca cgcctgtaaa gggattaaag 
0911 tggatcaggt actggatgcg gtcgggatct cgcgctccaa tcttgagaag cgttttaaag aagaggtggg 
0981 tgaaaccatc catgccatga ttcatgccga gaagctggag aaagcgcgca gtctgctgat ttcaaccacc 
1051 ttgtcgatca atgagatatc gcaaatgtgc ggttatccat cgctgcaata tttctactct gtttttaaaa 
1121 aagcatatga cacgacgcca aaagagtatc gcgatgtaaa tagcgaggtc atgttgtagC GATGATGAGA 
1191 ATTGTCGGCG TCACATCAGG TAACGCTGCG TGGTTGTCGG ATGCGGCGTG AACGCCTTAT CCGACCTACC 
1261 CGCCAGGCAT GATAAAACG