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PEC Original Annotations
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|
Essentiality
|
|
Class
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non-essential
|
|
References (PMID)
|
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
|
|
|
Deletion
|
2-2
(LD)
,
OCL09,11-1 (LD 2-2'_CRS)
(D)
,
OCL09,11-2 (LD 2-2'_P/O)
(D)
,
OCL10
(D)
,
OCL11
(D)
|
|
Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
xylA
|
|
Related strains
|
|
Strains Search
|
Search strains by gene name:
xylA
Search strains by all related name:
xylA b3565 ECK3554 JW3537
|
General information (Go to Linear View: )
|
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Gene Name
|
xylA
|
|
Alternative name
|
b3565,ECK3554,JW3537
|
|
Location, Length
|
3,727,466 - 3,728,788
(
-
)
;
80.34
min
;
1323
(bp) ,
440
(aa)
|
|
Product
|
D-xylose isomerase
|
|
Operon Name
|
xylAB
|
|
Note
|
GO_component: GO:0005737 - cytoplasm; GO_process: GO:0016052 - carbohydrate catabolic process; GO_process: GO:0006006 - glucose metabolic process
|
|
Function
|
enzyme; Degradation of small molecules: Carbon compounds
|
|
Gene Ontology
|
GO:0000287
;
magnesium ion binding ( xylA )
GO:0005737
;
cytoplasm ( xylA )
GO:0005975
;
carbohydrate metabolic process ( xylA )
GO:0006098
;
pentose-phosphate shunt ( xylA )
GO:0009045
;
xylose isomerase activity ( xylA )
GO:0016853
;
isomerase activity ( xylA )
GO:0042732
;
D-xylose metabolic process ( xylA )
GO:0046872
;
metal ion binding ( xylA )
|
|
PID
|
1789988
|
EC number
(KEGG Pathway)
|
5.3.1.5
|
|
SWISS-PROT
(
Show details
[
2
more]
)
|
Entry name(Acc.no)
|
XYLA_ECOLI
(
P00944
;
P00945
)
|
|
- Protein name
|
Xylose isomerase
|
|
- Synonyms
|
EC 5.3.1.5, D-xylulose keto-isomerase
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- Gene name
|
Name=xylA; OrderedLocusNames=b3565;
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Homology Analysis
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BLAST
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Bacteria
|
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GTOP
|
xylA
(
homologous genes of other bacterias
)
|
|
PDB
(database updated :
2007.02.20
)
|
|
PSI-BLAST
|
Chain A, Xylose Isomerase From Thermoanaerobacterium Thermosulfurigenes
|
|
SWISS-PROT
(database updated :
2007.02.20
)
|
|
BLAST
|
Xylose isomerase
|
|
PSI-BLAST
|
Xylose isomerase
|
|
nr
(database updated :
2007.02.20
)
|
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BLAST
|
unnamed protein product [Escherichia coli]
|
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Pfam 28.0
(database updated :
2015-05
)
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Pfam
|
|
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PROSITE
|
|
PROSITE
|
CAMP_PHOSPHO_SITE
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
MYRISTYL
AMIDATION
RGD
XYLOSE_ISOMERASE_1
XYLOSE_ISOMERASE_2
|
|
MMBR References
|
Agric. Biol. Chem. 1987;51:2575-2578.
Cloning of the D-xylose uptake gene linked to the xylA gene in Escherichia coli.
Kurose, N., K. Murata, and A. Kimura.
|
Appl Environ Microbiol. 1984;47(1):15-21.
Cloning and sequencing of the xylose isomerase and xylulose kinase genes of Escherichia coli.
Lawlis VB, Dennis MS, Chen EY, Smith DH, Henner DJ.
(
6320721
)
|
Can J Biochem. 1982;60(2):144-51.
A Col E1 hybrid plasmid containing Escherichia coli genes complementing d-xylose negative mutants of Escherichia coli and Salmonella typhimurium.
Maleszka R, Wang PY, Schneider H.
(
6282416
)
|
Mol Gen Genet. 1984;194(3):410-5.
Cloning and characterization of the xyl genes from Escherichia coli.
Rosenfeld SA, Stevis PE, Ho NW.
(
6330500
)
|
J Biol Chem. 1984;259:6826-6832
Xylose isomerase from Escherichia coli. Characterization of the protein and the structural gene.
Schellenberg, G. D., A. Sarthy, A. E. Larson, M. P. Backer, J. W. Crabb, M. Lidstrom, B. D. Hall, and C. E. Furlong.
|
Nucleic Acids Res. 1994;22:2576-2586
Analysis of the Escherichia coli genome. V. DNA sequence of the region from 76.0 to 81.5 minutes.
Sofia, H. J., V. D. Burland, D. L. Daniels, G. Plunkett, and F. R. Blattner.
|
EMBO J. 1984;3:611-616
Molecular cloning, DNA structure and expression of the Escherichia coli D-xylose isomerase.
Briggs, K. A., W. E. Lancashire, and B. S. Hartley.
|
| Sequences |
Amino acid
FASTA format
|
0001 MQAYFDQLDR VRYEGSKSSN PLAFRHYNPD ELVLGKRMEE HLRFAACYWH TFCWNGADMF GVGAFNRPWQ
0071 QPGEALALAK RKADVAFEFF HKLHVPFYCF HDVDVSPEGA SLKEYINNFA QMVDVLAGKQ EESGVKLLWG
0141 TANCFTNPRY GAGAATNPDP EVFSWAATQV VTAMEATHKL GGENYVLWGG REGYETLLNT DLRQEREQLG
0211 RFMQMVVEHK HKIGFQGTLL IEPKPQEPTK HQYDYDAATV YGFLKQFGLE KEIKLNIEAN HATLAGHSFH
0281 HEIATAIALG LFGSVDANRG DAQLGWDTDQ FPNSVEENAL VMYEILKAGG FTTGGLNFDA KVRRQSTDKY
0351 DLFYGHIGAM DTMALALKIA ARMIEDGELD KRIAQRYSGW NSELGQQILK GQMSLADLAK YAQEHHLSPV
0421 HQSGRQEQLE NLVNHYLFDK
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 aatagcagtg tgaaataaca taattgagca
-070 actgaaaggg agtgcccaat attacgacat catccatcac ccgcggcatt acctgattat ggagttcaat
0001 atgcaagcct attttgacca gctcgatcgc gttcgttatg aaggctcaaa atcctcaaac ccgttagcat
0071 tccgtcacta caatcccgac gaactggtgt tgggtaagcg tatggaagag cacttgcgtt ttgccgcctg
0141 ctactggcac accttctgct ggaacggggc ggatatgttt ggtgtggggg cgtttaatcg tccgtggcag
0211 cagcctggtg aggcactggc gttggcgaag cgtaaagcag atgtcgcatt tgagtttttc cacaagttac
0281 atgtgccatt ttattgcttc cacgatgtgg atgtttcccc tgagggcgcg tcgttaaaag agtacatcaa
0351 taattttgcg caaatggttg atgtcctggc aggcaagcaa gaagagagcg gcgtgaagct gctgtgggga
0421 acggccaact gctttacaaa ccctcgctac ggcgcgggtg cggcgacgaa cccagatcct gaagtcttca
0491 gctgggcggc aacgcaagtt gttacagcga tggaagcaac ccataaattg ggcggtgaaa actatgtcct
0561 gtggggcggt cgtgaaggtt acgaaacgct gttaaatacc gacttgcgtc aggagcgtga acaactgggc
0631 cgctttatgc agatggtggt tgagcataaa cataaaatcg gtttccaggg cacgttgctt atcgaaccga
0701 aaccgcaaga accgaccaaa catcaatatg attacgatgc cgcgacggtc tatggcttcc tgaaacagtt
0771 tggtctggaa aaagagatta aactgaacat tgaagctaac cacgcgacgc tggcaggtca ctctttccat
0841 catgaaatag ccaccgccat tgcgcttggc ctgttcggtt ctgtcgacgc caaccgtggc gatgcgcaac
0911 tgggctggga caccgaccag ttcccgaaca gtgtggaaga gaatgcgctg gtgatgtatg aaattctcaa
0981 agcaggcggt ttcaccaccg gtggtctgaa cttcgatgcc aaagtacgtc gtcaaagtac tgataaatat
1051 gatctgtttt acggtcatat cggcgcgatg gatacgatgg cactggcgct gaaaattgca gcgcgcatga
1121 ttgaagatgg cgagctggat aaacgcatcg cgcagcgtta ttccggctgg aatagcgaat tgggccagca
1191 aatcctgaaa ggccaaatgt cactggcaga tttagccaaa tatgctcagg aacatcattt gtctccggtg
1261 catcagagtg gtcgccagga acaactggaa aatctggtaa accattatct gttcgacaaa taacggctaa
1331 ctgtgcagtc cgttggcccg gttatcggta gcgataccgg gcattttttt aaggaacgat cgatatgtat
1401 atcgggatag atcttggcac ctc
|
