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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
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Deletion
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DE(bioH-asd)29
,
OCL18,19-8 (AK1-13 / BK2-13)
(D)
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Related gene (W3110 PEC)
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Gene Search
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Search MG1655 PEC by gene name:
glgC
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Related strains
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Strains Search
|
Search strains by gene name:
glgC
Search strains by all related name:
glgC b3430 ECK3416 f431 JW3393
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General information (Go to Linear View: )
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Gene Name
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glgC
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Alternative name
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b3430,ECK3416,f431,JW3393
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Location, Length
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3,566,056 - 3,567,351
(
-
)
;
76.86
min
;
1296
(bp) ,
431
(aa)
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Product
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glucose-1-phosphate adenylyltransferase
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Operon Name
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glgBXCAP
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Note
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GO_component: GO:0005737 - cytoplasm; GO_process: GO:0000271 - polysaccharide biosynthetic process
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Function
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enzyme; Macromolecule synthesis, modification: Polysaccharides - (cytoplasmic)
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Gene Ontology
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GO:0003824
;
catalytic activity ( glgC )
GO:0005515
;
protein binding ( glgC )
GO:0005978
;
glycogen biosynthetic process ( glgC )
GO:0008878
;
glucose-1-phosphate adenylyltransferase activity ( glgC )
GO:0009058
;
biosynthetic process ( glgC )
GO:0016740
;
transferase activity ( glgC )
GO:0016779
;
nucleotidyltransferase activity ( glgC )
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PID
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1789837
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EC number
(KEGG Pathway)
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2.7.7.27
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Verified Protein Starts
(data
compiled from literature and appropriate citations are available from EcoGene)
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EcoGene
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glgC
(
EG10379
)
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Number of removed
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1 aa cleaved
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SWISS-PROT
(
Show details
)
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Entry name(Acc.no)
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GLGC_ECOLI
(
P00584
)
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- Protein name
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Glucose-1-phosphate adenylyltransferase
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- Synonyms
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EC 2.7.7.27, ADP-glucose synthase, ADP-glucose pyrophosphorylase, ADPGlc PPase
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- Gene name
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OrderedLocusNames=b3430, c4217, z4792, ECs4275, SF3453, S4310;
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MMBR References
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J Biol Chem. 1986;258:5084-5088
Biosynthesis of bacterial glycogen: primary structure of Escherichia coli ADP-glucose synthetase as deduced from the nucleotide sequence of the glgC gene.
Baecker, P. A., C. E. Furlong, and J. Preiss.
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Mol Gen Genet. 1977;150(3):325-8.
Relative order of glg mutations affecting glycogen biosynthesis in Escherichia coli K12.
Latil-Damotte M, Lares C.
(
321940
)
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J Biol Chem. 1981;256:6944-6952
Biosynthesis of bacterial glycogen. Cloning of the glycogen biosynthetic enzyme structural genes of Escherichia coli.
Okita, T. W., R. L. Rodriguez, and J. Preiss.
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Gene. 1988;70(2):363-76.
Analysis of the Escherichia coli glycogen gene cluster suggests that catabolic enzymes are encoded among the biosynthetic genes.
Romeo T, Kumar A, Preiss J.
(
2975249
)
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Gene. 1991;108(1):23-9.
A simple method for cloning genes involved in glucan biosynthesis: isolation of structural and regulatory genes for glycogen synthesis in Escherichia coli.
Romeo T, Moore J, Smith J.
(
1662181
)
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| Sequences |
Amino acid
FASTA format
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0001 MVSLEKNDHL MLARQLPLKS VALILAGGRG TRLKDLTNKR AKPAVHFGGK FRIIDFALSN CINSGIRRMG
0071 VITQYQSHTL VQHIQRGWSF FNEEMNEFVD LLPAQQRMKG ENWYRGTADA VTQNLDIIRR YKAEYVVILA
0141 GDHIYKQDYS RMLIDHVEKG ARCTVACMPV PIEEASAFGV MAVDENDKII EFVEKPANPP SMPNDPSKSL
0211 ASMGIYVFDA DYLYELLEED DRDENSSHDF GKDLIPKITE AGLAYAHPFP LSCVQSDPDA EPYWRDVGTL
0281 EAYWKANLDL ASVVPELDMY DRNWPIRTYN ESLPPAKFVQ DRSGSHGMTL NSLVSGGCVI SGSVVVQSVL
0351 FSRVRVNSFC NIDSAVLLPE VWVGRSCRLR RCVIDRACVI PEGMVIGENA EEDARRFYRS EEGIVLVTRE
0421 MLRKLGHKQE R
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Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 ccccattcgc tggagaggat aacccagtga
-070 ttacggctgt ctggcaggga cctgcacacg gattgtgtgt gttccagaga tgataaaaaa ggagttagtc
0001 atggttagtt tagagaagaa cgatcactta atgttggcgc gccagctgcc attgaaatct gttgccctga
0071 tactggcggg aggacgtggt acccgcctga aggatttaac caataagcga gcaaaaccgg ccgtacactt
0141 cggcggtaag ttccgcatta tcgactttgc gctgtctaac tgcatcaact ccgggatccg tcgtatgggc
0211 gtgatcaccc agtaccagtc ccacactctg gtgcagcaca ttcagcgcgg ctggtcattc ttcaatgaag
0281 aaatgaacga gtttgtcgat ctgctgccag cacagcagag aatgaaaggg gaaaactggt atcgcggcac
0351 cgcagatgcg gtcacccaaa acctcgacat tatccgccgt tataaagcgg aatacgtggt gatcctggcg
0421 ggcgaccata tctacaagca agactactcg cgtatgctta tcgatcacgt cgaaaaaggc gcacgttgca
0491 ccgttgcttg tatgccagta ccgattgaag aagcctccgc atttggcgtt atggcggttg atgagaacga
0561 taaaattatc gaattcgttg aaaaacctgc taacccgccg tcaatgccga acgatccgag caaatctctg
0631 gcgagtatgg gtatctacgt ctttgacgcc gactatctgt atgaactgct ggaagaagac gatcgcgatg
0701 agaactccag ccacgacttt ggcaaagatt tgattcccaa gatcaccgaa gccggtctgg cctatgcgca
0771 cccgttcccg ctctcttgcg tacaatccga cccggatgcc gagccgtact ggcgcgatgt gggtacgctg
0841 gaagcttact ggaaagcgaa cctcgatctg gcctctgtgg tgccggaact ggatatgtac gatcgcaatt
0911 ggccaattcg cacctacaat gaatcattac cgccagcgaa attcgtgcag gatcgctccg gtagccacgg
0981 gatgaccctt aactcactgg tttccggcgg ttgtgtgatc tccggttcgg tggtggtgca gtccgttctg
1051 ttctcgcgcg ttcgcgtgaa ttcattctgc aacattgatt ccgccgtatt gttaccggaa gtatgggtag
1121 gtcgctcgtg ccgtctgcgc cgctgcgtca tcgatcgtgc ttgtgttatt ccggaaggca tggtgattgg
1191 tgaaaacgca gaggaagatg cacgtcgttt ctatcgttca gaagaaggca tcgtgctggt aacgcgcgaa
1261 atgctacgga agttagggca taaacaggag cgataatgca ggttttacat gtatgttcag agatgttccc
1331 gctgcttaaa accggcggtc tggctgatgt tattggggca ttacccgcag cacaaatcgc agacgg
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