MG1655
W3110
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Gene Report : malQ
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)  
     Deletion DE(envZ-malT)176  ,  OCL18,19-1 (D)  ,  DE(bioH-asd)29  
Related gene (W3110 PEC)
     Gene Search Search MG1655 PEC by gene name:  malQ
Related strains
     Strains Search Search strains by gene name:  malQ   Search strains by all related name:  malQ b3416 ECK3403 f694 JW3379 malA

General information  (Go to Linear View:)
 Gene Name malQ  
 Alternative name b3416,ECK3403,f694,JW3379,malA  
 Location, Length 3,546,008 - 3,548,092 (  -  ) ;   76.43 min ; 2085 (bp) ,   694 (aa) Go to Linear View
 Product 4-alpha-glucanotransferase (amylomaltase)  
 Operon Name malPQ  
 Note GO_component: GO:0005737 - cytoplasm; GO_process: GO:0016052 - carbohydrate catabolic process; GO_process: GO:0000272 - polysaccharide catabolic process  
 Function enzyme; Degradation of polysaccharides  
 Gene Ontology GO:0003824 ; catalytic activity ( malQ )
GO:0004134 ; 4-alpha-glucanotransferase activity ( malQ )
GO:0005737 ; cytoplasm ( malQ )
GO:0005975 ; carbohydrate metabolic process ( malQ )
GO:0016740 ; transferase activity ( malQ )
GO:0016757 ; transferase activity, transferring glycosyl groups ( malQ )
GO:0043169 ; cation binding ( malQ )
 PID 1789821  
 EC number
  (KEGG Pathway)
 
2.4.1.25  
SWISS-PROT  ( Show details [ 2 more] )
  botton Entry name(Acc.no) MALQ_ECOLI ( P15977 )
    -  Protein name 4-alpha-glucanotransferase  
    -  Synonyms EC 2.4.1.25, Amylomaltase, Disproportionating enzyme, D-enzyme  
    -  Gene name Name=malQ; Synonyms=malA; OrderedLocusNames=b3416;  

 Linear View (Whole Mode)
View Location
   3535.0  –  3560.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP malQ (  homologous genes of other bacterias  )  
    PDB     (database updated : 2007.02.20 )
         PSI-BLAST Chain A, Structure Determination And Refinement At 1.8 A Resolution Of Disproportionating Enzyme From Potato  
    SWISS-PROT     (database updated : 2007.02.20 )
         BLAST 4-alpha-glucanotransferase  
         PSI-BLAST 4-alpha-glucanotransferase
    nr     (database updated : 2007.02.20 )
         BLAST 4-alpha-glucanotransferase (amylomaltase) [Escherichia coli K12]  
Pfam 28.0   (database updated : 2015-05 )
    Pfam
PROSITE
    PROSITE CAMP_PHOSPHO_SITE    PKC_PHOSPHO_SITE    CK2_PHOSPHO_SITE    TYR_PHOSPHO_SITE    MYRISTYL    AMIDATION    ATP_GTP_A     

Other Cross-Reference
    EcoCyc malQ 

MMBR References
Mol Gen Genet. 1976;145(2):207-13.
lamB mutations in E. coli K12: growth of lambda host range mutants and effect of nonsense suppressors.
Hofnung M, Jezierska A, Braun-Breton C. ( 778586 )
J Bacteriol. 1981;148(3):853-60.
General method for fine mapping of the Escherichia coli K-12 lamB gene: localization of missense mutations affecting bacteriophage lambda adsorption.
Hofnung M, Lepouce E, Braun-Breton C. ( 6458595 )
J Mol Biol. 1971;61(3):681-94.
Complementation studies in the maltose-A region of the Escherichia coli K12 genetic map.
Hofnung M, Schwartz M, Hatfield D. ( 4943758 )
Mol Microbiol. 1988;2(4):473-9.
Molecular characterization of malQ, the structural gene for the Escherichia coli enzyme amylomaltase.
Pugsley AP, Dubreuil C. ( 2845225 )
J Bacteriol. 1966;92(4):1083-9.
Location of the maltose A and B loci on the genetic map of Escherichia coli.
Schwartz M. ( 5332865 )

Sequences
Amino acid
FASTA format
0001 MESKRLDNAA LAAGISPNYI NAHGKPQSIS AETKRRLLDA MHQRTATKVA VTPVPNVMVY TSGKKMPMVV 
0071 EGSGEYSWLL TTEEGTQYKG HVTGGKAFNL PTKLPEGYHT LTLTQDDQRA HCRVIVAPKR CYEPQALLNK 
0141 QKLWGACVQL YTLRSEKNWG IGDFGDLKAM LVDVAKRGGS FIGLNPIHAL YPANPESASP YSPSSRRWLN 
0211 VIYIDVNAVE DFHLSEEAQA WWQLPTTQQT LQQARDADWV DYSTVTALKM TALRMAWKGF AQRDDEQMAA 
0281 FRQFVAEQGD SLFWQAAFDA LHAQQVKEDE MRWGWPAWPE MYQNVDSPEV RQFCEEHRDD VDFYLWLQWL 
0351 AYSQFAACWE ISQGYEMPIG LYRDLAVGVA EGGAETWCDR ELYCLKASVG APPDILGPLG QNWGLPPMDP 
0421 HIITARAYEP FIELLRANMQ NCGALRIDHV MSMLRLWWIP YGETADQGAY VHYPVDDLLS ILALESKRHR 
0491 CMVIGEDLGT VPVEIVGKLR SSGVYSYKVL YFENDHEKTF RAPKAYPEQS MAVAATHDLP TLRGYWECGD 
0561 LTLGKTLGLY PDEVVLRGLY QDRELAKQGL LDALHKYGCL PKRAGHKASL MSMTPTLNRG LQRYIADSNS 
0631 ALLGLQPEDW LDMAEPVNIP GTSYQYKNWR RKLSATLESM FADDGVNKLL KDLDRRRRAA AKKK

Nucleotide
FASTA format

View sequence out neighbor 100bp
-100                                             ggcgatcctc aataccgccc gctgcggtat 
-070 gtttagctcg gatcgctcta ttcgcgatta tcaggctcgt atctggcagg caaaacgcta aggaagctcg 
0001 atggaaagca aacgtctgga taatgccgcg ctggcggcgg ggattagccc caattacatc aatgcccacg 
0071 gtaaaccgca gtcgattagc gccgaaacca aacggcgttt gcttgacgcg atgcatcaac gtaccgccac 
0141 gaaagtggcg gtaacgccag tcccgaatgt catggtttat accagcggca aaaaaatgcc gatggtggtg 
0211 gagggcagcg gcgaatatag ctggctgctg accaccgaag aaggaacgca gtacaaaggc catgtaacgg 
0281 ggggcaaagc gttcaatcta ccgacgaagc tgccggaagg ttatcacacg ctgacactca cccaggacga 
0351 ccagcgcgcg cattgccggg tgattgtcgc cccgaaacgc tgttacgaac cgcaggcgtt gctgaataaa 
0421 caaaagctgt ggggtgcctg cgttcagctt tatacgctgc gatcggaaaa aaactggggt attggggatt 
0491 ttggcgatct caaagcgatg ctggtggatg tggcaaaacg tggcgggtcg ttcattggcc tgaacccgat 
0561 tcatgcgctc tatccggcaa atccggagag cgccagccca tacagcccgt cttctcgccg ttggctgaat 
0631 gtgatttata tcgacgttaa cgccgttgaa gatttccatc ttagcgaaga ggctcaggcc tggtggcagt 
0701 tgccgaccac gcaacagacg ctgcaacagg cgcgcgatgc cgactgggtc gattactcca cggttaccgc 
0771 cctaaaaatg acagcattac gaatggcgtg gaaaggtttc gcgcaacgtg atgatgagca gatggccgcg 
0841 tttcgccagt ttgttgcaga gcagggcgac agcctgttct ggcaggcagc ctttgatgcg ctacatgccc 
0911 agcaagtgaa agaggacgaa atgcgctggg gctggcctgc atggccagag atgtatcaga acgtggattc 
0981 accagaagtg cgtcagttct gcgaagaaca tcgtgatgac gtcgattttt atctctggtt gcagtggctg 
1051 gcttacagcc agtttgccgc ctgctgggag ataagccagg gctatgaaat gccgattggc ttgtatcgtg 
1121 atctggcggt tggcgtagcg gaaggtgggg cggaaacctg gtgtgaccgt gaactatatt gcctgaaagc 
1191 atcggttggc gcgccgccgg atatcctcgg cccgttgggg cagaactggg gattaccgcc aatggacccg 
1261 catatcatca ccgcgcgtgc ctatgaaccg tttatcgagc tgttgcgtgc caatatgcaa aactgcggcg 
1331 cattacgaat tgaccatgtg atgtcgatgc tgcgtttgtg gtggataccg tatggcgaga cggcagatca 
1401 gggcgcgtat gttcactatc cggtggatga tctgctctcg attctggcac tcgaaagtaa acgtcatcgc 
1471 tgtatggtga ttggtgaaga tctcggtacc gtaccggtag agattgtcgg taagctgcgc agcagcggtg 
1541 tgtactctta caaagtgctc tatttcgaaa acgaccacga gaagacgttc cgtgcaccga aagcgtatcc 
1611 ggagcagtcg atggcggttg cggcgacaca tgacctgcca acgctgcgcg gttactggga gtgcggggat 
1681 ctaacgctgg gcaaaaccct ggggctgtat ccggatgaag tggtactgcg cggtctgtat caggatcgcg 
1751 aactggcgaa gcaagggctg ctggatgcac tgcataaata tggttgtctg ccgaaacgtg ccgggcataa 
1821 ggcatcgttg atgtcgatga cgccgacgct gaaccgtggt ttgcagcgct acattgccga cagtaacagt 
1891 gctctgttag gactacagcc ggaagactgg ctggatatgg ccgaaccggt gaatattcct ggcaccagtt 
1961 accagtataa aaactggcga cgcaagcttt ccgcaacgct tgagtcgatg tttgccgatg atggcgtgaa 
2031 caagttgctg aaggatttgg acagacggcg cagagctgca gcgaagaaga agtagagtgc ggttgatgcc 
2101 ggatgcgatg cttgacgcgt cttatccggc ctactaattc atcccgaatc gtaggccgga taaggcggtc 
2171 acgccgcatc cggca