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PEC Original Annotations
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Essentiality
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|
Class
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non-essential
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References (PMID)
|
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
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Deletion
|
OCL19,20-1
(D)
,
OCL19,20-2
(D)
,
OCL19,20-3
(D)
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Related gene (W3110 PEC)
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Gene Search
|
Search MG1655 PEC by gene name:
dam
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Related strains
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Strains Search
|
Search strains by gene name:
dam
Search strains by all related name:
dam b3387 ECK3374 f278 JW3350
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General information (Go to Linear View: )
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Gene Name
|
dam
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Alternative name
|
b3387,ECK3374,f278,JW3350
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Location, Length
|
3,513,099 - 3,513,935
(
-
)
;
75.72
min
;
837
(bp) ,
278
(aa)
|
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Product
|
DNA adenine methyltransferase
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Operon Name
|
aroKB-damX-dam-rpe-gph-trpS
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Note
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GO_component: GO:0005737 - cytoplasm; GO_process: GO:0006306 - DNA methylation
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Function
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enzyme; DNA - replication, repair,restriction/modification
|
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Gene Ontology
|
GO:0003676
;
nucleic acid binding ( dam )
GO:0003677
;
DNA binding ( dam )
GO:0006260
;
DNA replication ( dam )
GO:0006306
;
DNA methylation ( dam )
GO:0008168
;
methyltransferase activity ( dam )
GO:0009007
;
site-specific DNA-methyltransferase (adenine-specific) activity ( dam )
GO:0016740
;
transferase activity ( dam )
GO:0032259
;
methylation ( dam )
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PID
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1789789
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EC number
(KEGG Pathway)
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2.1.1.72
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SWISS-PROT
(
Show details
[
1
more]
)
|
Entry name(Acc.no)
|
DMA_ECOLI
(
P00475
)
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- Protein name
|
DNA adenine methylase
|
|
- Synonyms
|
EC 2.1.1.72, Deoxyadenosyl-methyltransferase, DNA adenine methyltransferase, M.EcoDam
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- Gene name
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Name=dam; OrderedLocusNames=b3387, z4740, ECs4229;
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MMBR References
|
J Bacteriol. 1983;153(1):562-5.
Phenotypic reversal in dam mutants of Escherichia coli K-12 by a recombinant plasmid containing the dam+ gene.
Arraj JA, Marinus MG.
(
6336742
)
|
J Bacteriol. 1981;148(3):941-9.
Cloning and characterization of the gene for Escherichia coli tryptophanyl-transfer ribonucleic acid synthetase.
Hall CV, Yanofsky C.
(
6171561
)
|
Mol Gen Genet. 1980;178(2):309-15.
Isolation and characterization of Dam+ revertants and suppressor mutations that modify secondary phenotypes of dam-3 strains of Escherichia coli K-12.
McGraw BR, Marinus MG.
(
6993844
)
|
J Bacteriol. 1993;175:7505-7508
Analysis of the genetic requirements for viability of Escherichia coli K-12 DNA adenine methylase (dam) mutants.
Peterson, K. R., and D. W. Mount.
|
Nucleic Acids Res. 1983;11:837-851
The isolation and characterization of the Escherichia coli DNA adenine methylase (dam) gene.
Brooks, J. E., R. M. Blumenthal, and T. R. Gingeras.
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| Sequences |
Amino acid
FASTA format
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0001 MKKNRAFLKW AGGKYPLLDD IKRHLPKGEC LVEPFVGAGS VFLNTDFSRY ILADINSDLI SLYNIVKMRT
0071 DEYVQAAREL FVPETNCAEV YYQFREEFNK SQDPFRRAVL FLYLNRYGYN GLCRYNLRGE FNVPFGRYKK
0141 PYFPEAELYH FAEKAQNAFF YCESYADSMA RADDASVVYC DPPYAPLSAT ANFTAYHTNS FTLEQQAHLA
0211 EIAEGLVERH IPVLISNHDT MLTREWYQRA KLHVVKVRRS ISSNGGTRKK VDELLALYKP GVVSPAKK
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Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 ttatctcccg caatggttta tcgttgcggg
-070 agttgcctga agcgctggat gctgtcggag ctttctccac agccggagaa ggtgtaatta gttagtcagc
0001 atgaagaaaa atcgcgcttt tttgaagtgg gcagggggca agtatcccct gcttgatgat attaaacggc
0071 atttgcccaa gggcgaatgt ctggttgagc cttttgtagg tgccgggtcg gtgtttctca acaccgactt
0141 ttctcgttat atccttgccg atatcaatag cgacctgatc agtctctata acattgtgaa gatgcgtact
0211 gatgagtacg tacaggccgc acgcgagctg tttgttcccg aaacaaattg cgccgaggtt tactatcagt
0281 tccgcgaaga gttcaacaaa agccaggatc cgttccgtcg ggcggtactg tttttatatt tgaaccgcta
0351 cggttacaac ggcctgtgtc gttacaatct gcgcggtgag tttaacgtgc cgttcggccg ctacaaaaaa
0421 ccctatttcc cggaagcaga gttgtatcac ttcgctgaaa aagcgcagaa tgcctttttc tattgtgagt
0491 cttacgccga tagcatggcg cgcgcagatg atgcatccgt cgtctattgc gatccgcctt atgcaccgct
0561 gtctgcgacc gccaacttta cggcgtatca cacaaacagt tttacgcttg aacaacaagc gcatctggcg
0631 gagatcgccg aaggtctggt tgagcgccat attccagtgc tgatctccaa tcacgatacg atgttaacgc
0701 gtgagtggta tcagcgcgca aaattgcatg tcgtcaaagt tcgacgcagt ataagcagca acggcggcac
0771 acgtaaaaag gtggacgaac tgctggcttt gtacaaacca ggagtcgttt cacccgcgaa aaaataattc
0841 tcaaggagaa gcggatgaaa cagtatttga ttgccccctc aattctgtcg gctgattttg cccgcctggg
0911 tgaagatacc gcaaaagccc tggcagc
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