|
PEC Original Annotations
|
|
Essentiality
|
|
Class
|
non-essential
|
|
References (PMID)
|
|
|
Deletion
|
9-1
(LD)
,
DE(gpt-lac)5
,
DE(argF-lac)169
,
OCR36,37-6 (LD 9C::Ap)
(D)
|
|
Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
prpC
|
|
Related strains
|
|
Strains Search
|
Search strains by gene name:
prpC
Search strains by all related name:
prpC b0333 ECK0330 JW0324 o389 yahS yzzD
|
General information (Go to Linear View: )
|
|
Gene Name
|
prpC
|
|
Alternative name
|
b0333,ECK0330,JW0324,o389,yahS,yzzD
|
|
Location, Length
|
349,236 - 350,405
(
+
)
;
7.53
min
;
1170
(bp) ,
389
(aa)
|
|
Product
|
2-methylcitrate synthase
|
|
Operon Name
|
prpBCDE
|
|
Note
|
putative citrate synthase; propionate metabolism?; GO_component: GO:0005737 - cytoplasm; GO_process: GO:0019395 - fatty acid oxidation
|
|
Function
|
putative enzyme; Not classified
|
|
Gene Ontology
|
GO:0005737
;
cytoplasm ( prpC )
GO:0016740
;
transferase activity ( prpC )
GO:0044262
;
cellular carbohydrate metabolic process ( prpC )
GO:0046912
;
transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer ( prpC )
GO:0050440
;
2-methylcitrate synthase activity ( prpC )
|
|
PID
|
1786527
|
EC number
(KEGG Pathway)
|
2.3.3.1
|
|
Verified Protein Starts
(data
compiled from literature and appropriate citations are available from EcoGene)
|
|
EcoGene
|
prpC
(
EG11756
)
|
|
Number of removed
|
17 aa cleaved
|
|
SWISS-PROT
(
Show details
[
2
more]
)
|
Entry name(Acc.no)
|
PRPC_ECOLI
(
P31660
;
P77217
)
|
|
- Protein name
|
2-methylcitrate synthase
|
|
- Synonyms
|
EC 2.3.3.5, Methylcitrate synthase, Citrate synthase 2
|
|
- Gene name
|
Name=prpC; OrderedLocusNames=b0333;
|
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Homology Analysis
|
|
BLAST
|
|
Bacteria
|
|
GTOP
|
prpC
(
homologous genes of other bacterias
)
|
|
PDB
(database updated :
2007.02.20
)
|
|
PSI-BLAST
|
Chain A, Crystal Structure Of Citrate Synthase From Thermus Thermophilus Hb8
|
|
SWISS-PROT
(database updated :
2007.02.20
)
|
|
BLAST
|
2-methylcitrate synthase
|
|
PSI-BLAST
|
Citrate synthase
|
|
nr
(database updated :
2007.02.20
)
|
|
BLAST
|
2-methylcitrate synthase [Escherichia coli K12]
|
|
Pfam 28.0
(database updated :
2015-05
)
|
|
Pfam
|
|
|
PROSITE
|
|
PROSITE
|
ASN_GLYCOSYLATION
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
TYR_PHOSPHO_SITE
MYRISTYL
ATP_GTP_A
CITRATE_SYNTHASE
|
| Sequences |
Amino acid
FASTA format
|
0001 MSDTTILQNS THVIKPKKSV ALSGVPAGNT ALCTVGKSGN DLHYRGYDIL DLAKHCEFEE VAHLLIHGKL
0071 PTRDELAAYK TKLKALRGLP ANVRTVLEAL PAASHPMDVM RTGVSALGCT LPEKEGHTVS GARDIADKLL
0141 ASLSSILLYW YHYSHNGERI QPETDDDSIG GHFLHLLHGE KPSQSWEKAM HISLVLYAEH EFNASTFTSR
0211 VIAGTGSDMY SAIIGAIGAL RGPKHGGANE VSLEIQQRYE TPDEAEADIR KRVENKEVVI GFGHPVYTIA
0281 DPRHQVIKRV AKQLSQEGGS LKMYNIADRL ETVMWESKKM FPNLDWFSAV SYNMMGVPTE MFTPLFVIAR
0351 VTGWAAHIIE QRQDNKIIRP SANYVGPEDR PFVALDKRQ
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 AGGCCTACGG GGTGAACTGA ACTGTAGGTC
-070 GGATAAGACG CATAGCGTCG CATCCGACAA CAATCTCGAC CCTACAAATG ATAACAATGA CGAGGACAAC
0001 atgagcgaca caacgatcct gcaaaacagt acccatgtca ttaaaccgaa aaaatctgtg gcactttctg
0071 gcgttccggc gggcaatacg gcgctctgca ccgtgggtaa aagtggcaat gacctgcatt accgcggcta
0141 cgatattctt gatctggcga aacattgcga atttgaagaa gtggcgcatc tgctgatcca cggcaaactg
0211 ccgacccgtg acgaactcgc cgcttacaaa acgaaactga aagccctgcg cggtttaccg gctaacgtgc
0281 gtaccgtgct ggaagcctta ccggcggcgt cgcacccgat ggatgttatg cgcaccggtg tttccgcgct
0351 cggctgcacg ctgccagaaa aagaggggca taccgtctct ggcgcgcggg atattgccga caaactgctg
0421 gcgtcgctta gctcgattct cctttattgg tatcactaca gccacaacgg cgaacgcatc caaccggaaa
0491 ccgatgacga ctccatcggc ggtcacttcc tgcatctgct gcacggcgaa aagccatcgc aaagctggga
0561 aaaggcgatg catatctcgc tggtgctgta cgccgaacac gagtttaacg cctccacctt taccagtcgg
0631 gtgattgcgg gcaccggctc tgatatgtat tccgcgatta ttggcgcgat tggcgcactg cgcgggccaa
0701 aacacggcgg ggcgaatgaa gtgtcgctgg agatccagca acgctacgaa acgccggacg aagccgaagc
0771 agatatccgc aagcgcgtgg aaaacaaaga agtggtcatt ggttttggtc atccggttta caccatcgct
0841 gacccgcgcc accaggtgat taaacgtgtg gcgaagcagc tctcgcagga aggcggctcg ctgaagatgt
0911 acaacatcgc cgatcgcctg gaaacggtga tgtgggagag caaaaagatg ttccccaatc tcgactggtt
0981 ctctgctgtt tcctacaaca tgatgggcgt tcccaccgag atgttcacac cactgtttgt tatcgcccgc
1051 gtcaccggct gggcggcgca cattatcgaa caacgtcagg acaacaaaat tatccgtcct tccgccaatt
1121 atgttggacc ggaagaccgc ccgtttgtcg cgctggataa gcgccagtaa ACCTCTACGA ATAACAATAA
1191 GGAAACGTAC CCAATGTCAG CTCAAATCAA CAACATCCGC CCGGAATTTG ATCGTGAAAT CGTTGATATC
1261 GTCGATTACG
|
