|
PEC Original Annotations
|
|
Essentiality
|
|
Class
|
non-essential
|
|
References (PMID)
|
J Bacteriol. 1999;181(5):1415-28.
Ferritin mutants of Escherichia coli are iron deficient and growth impaired, and fur mutants are iron deficient.
Abdul-Tehrani H, Hudson AJ, Chang YS, Timms AR, Hawkins C, Williams JM, Harrison PM, Guest JR, Andrews SC.
(
10049371
)
|
|
|
Deletion
|
OCL22
(D)
,
OCL22-2
(D)
,
OCL22-6
(D)
|
|
Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
bfr
|
|
Related strains
|
|
Strains Search
|
Search strains by gene name:
bfr
Search strains by all related name:
bfr b3336 ECK3323 f158 JW3298
|
General information (Go to Linear View: )
|
|
Gene Name
|
bfr
|
|
Alternative name
|
b3336,ECK3323,f158,JW3298
|
|
Location, Length
|
3,464,271 - 3,464,747
(
-
)
;
74.67
min
;
477
(bp) ,
158
(aa)
|
|
Product
|
bacterioferritin, iron storage and detoxification protein
|
|
Operon Name
|
bfd-bfr
|
|
Note
|
bacterioferrin, an iron storage homoprotein; GO_component: GO:0005737 - cytoplasm; GO_process: GO:0006826 - iron ion transport
|
|
Function
|
carrier; Transport of small molecules: Cations
|
|
Gene Ontology
|
GO:0005488
;
binding ( bfr )
GO:0005506
;
iron ion binding ( bfr )
GO:0005624
;
membrane fraction ( bfr )
GO:0006826
;
iron ion transport ( bfr )
GO:0006879
;
cellular iron ion homeostasis ( bfr )
GO:0008199
;
ferric iron binding ( bfr )
GO:0016491
;
oxidoreductase activity ( bfr )
GO:0046872
;
metal ion binding ( bfr )
GO:0046914
;
transition metal ion binding ( bfr )
|
|
PID
|
1789733
|
EC number
(KEGG Pathway)
|
|
|
Verified Protein Starts
(data
compiled from literature and appropriate citations are available from EcoGene)
|
|
EcoGene
|
bfr
(
EG10113
)
|
|
Number of removed
|
0 aa cleaved
|
|
SWISS-PROT
(
Show details
)
|
Entry name(Acc.no)
|
BFR_ECOLI
(
P11056
;
O68931
)
|
|
- Protein name
|
Bacterioferritin
|
|
- Synonyms
|
BFR, Cytochrome B-1, Cytochrome B-557
|
|
- Gene name
|
Name=bfr; OrderedLocusNames=b3336, c4107;
|
|
Homology Analysis
|
|
BLAST
|
|
Bacteria
|
|
GTOP
|
bfr
(
homologous genes of other bacterias
)
|
|
PDB
(database updated :
2007.02.20
)
|
|
PSI-BLAST
|
Chain A, Bacterioferritin (Cytochrome B1)
|
|
SWISS-PROT
(database updated :
2007.02.20
)
|
|
BLAST
|
Bacterioferritin (BFR) (Cytochrome b-1) (Cytochrome b-557)
|
|
PSI-BLAST
|
Ferritin, mitochondrial precursor
|
|
nr
(database updated :
2007.02.20
)
|
|
BLAST
|
bacterioferritin, iron storage and detoxification protein [Escherichia coli K12]
|
|
Pfam 28.0
(database updated :
2015-05
)
|
|
Pfam
|
|
|
PROSITE
|
|
PROSITE
|
CK2_PHOSPHO_SITE
TYR_PHOSPHO_SITE
BACTERIOFERRITIN
|
|
MMBR References
|
J Bacteriol. 1989;171(7):3940-7.
Cloning, sequencing, and mapping of the bacterioferritin gene (bfr) of Escherichia coli K-12.
Andrews SC, Harrison PM, Guest JR.
(
2661540
)
|
| Sequences |
Amino acid
FASTA format
|
0001 MKGDTKVINY LNKLLGNELV AINQYFLHAR MFKNWGLKRL NDVEYHESID EMKHADRYIE RILFLEGLPN
0071 LQDLGKLNIG EDVEEMLRSD LALELDGAKN LREAIGYADS VHDYVSRDMM IEILRDEEGH IDWLETELDL
0141 IQKMGLQNYL QAQIREEG
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 agctgccgga gtttaaggag tccgcataaa
-070 cggagtgtgt tttttgactt actcgtaagc cgttctactc ttcaaagagt ggaagcgaag gagtcaaaaa
0001 atgaaaggtg atactaaagt tataaattat ctcaacaaac tgttgggaaa tgagcttgtc gcaatcaatc
0071 agtactttct ccatgcccga atgtttaaaa actggggtct caaacgtctc aatgatgtgg agtatcatga
0141 atccattgat gagatgaaac acgccgatcg ttatattgag cgcattcttt ttctggaagg tcttccaaac
0211 ttacaggacc tgggcaaact gaacattggt gaagatgttg aggaaatgct gcgttctgat ctggcacttg
0281 agctggatgg cgcgaagaat ttgcgtgagg caattggtta tgccgatagc gttcatgatt acgtcagccg
0351 cgatatgatg atagaaattt tgcgtgatga agaaggccat atcgactggc tggaaacgga acttgatctg
0421 attcagaaga tgggcctgca aaattatctg caagcacaga tccgcgaaga aggttgagcc gtgtcgggag
0491 ggagaaccct cccggttaat aagagatcca ggccagatac cccaggttta tcatgctgcc gagcgcaagc
0561 cacgggccga atgcgat
|
