|
PEC Original Annotations
|
|
Essentiality
|
|
Class
|
non-essential
|
|
References (PMID)
|
Biochem J. 1996;313 (Pt 3):941-50.
Comparative analysis of the QUTR transcription repressor protein and the three C-terminal domains of the pentafunctional AROM enzyme.
Lamb HK, Moore JD, Lakey JH, Levett LJ, Wheeler KA, Lago H, Coggins JR, Hawkins AR.
(
8611179
)
|
|
|
Deletion
|
OCL23
(D)
,
OCL23-14
(D)
|
|
Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
aroE
|
|
Related strains
|
|
Strains Search
|
Search strains by gene name:
aroE
Search strains by all related name:
aroE b3281 ECK3268 f272 JW3242
|
General information (Go to Linear View: )
|
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Gene Name
|
aroE
|
|
Alternative name
|
b3281,ECK3268,f272,JW3242
|
|
Location, Length
|
3,428,042 - 3,428,860
(
-
)
;
73.89
min
;
819
(bp) ,
272
(aa)
|
|
Product
|
dehydroshikimate reductase, NAD(P)-binding
|
|
Operon Name
|
yrdD-rimN-aroE-yrdB
|
|
Note
|
dehydroshikimate reductase; GO_process: GO:0009423 - chorismate biosynthetic process
|
|
Function
|
enzyme; Amino acid biosynthesis: Chorismate
|
|
Gene Ontology
|
GO:0003824
;
catalytic activity ( aroE )
GO:0004764
;
shikimate 5-dehydrogenase activity ( aroE )
GO:0005488
;
binding ( aroE )
GO:0005515
;
protein binding ( aroE )
GO:0005737
;
cytoplasm ( aroE )
GO:0008152
;
metabolic process ( aroE )
GO:0008652
;
amino acid biosynthetic process ( aroE )
GO:0009073
;
aromatic amino acid family biosynthetic process ( aroE )
GO:0016491
;
oxidoreductase activity ( aroE )
GO:0050661
;
NADP binding ( aroE )
|
|
PID
|
1789675
|
EC number
(KEGG Pathway)
|
1.1.1.25
|
|
Verified Protein Starts
(data
compiled from literature and appropriate citations are available from EcoGene)
|
|
EcoGene
|
aroE
(
EG10077
)
|
|
Number of removed
|
0 aa cleaved
|
|
SWISS-PROT
(
Show details
[
2
more]
)
|
Entry name(Acc.no)
|
AROE_ECOLI
(
P15770
)
|
|
- Protein name
|
Shikimate 5-dehydrogenase
|
|
- Synonyms
|
EC 1.1.1.25
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|
- Gene name
|
Name=aroE; OrderedLocusNames=b3281;
|
|
MMBR References
|
Biochem J. 1988;249(2):319-26.
Sequencing and overexpression of the Escherichia coli aroE gene encoding shikimate dehydrogenase.
Anton IA, Coggins JR.
(
3277621
)
|
Nucleic Acids Res. 1984;12:5813-5821
Nucleotide sequence of the rpoA-rplQ DNA of Escherichia coli: a second regulatory binding site for protein S4?
Meek, D. W., and R. S. Hayward.
|
| Sequences |
Amino acid
FASTA format
|
0001 METYAVFGNP IAHSKSPFIH QQFAQQLNIE HPYGRVLAPI NDFINTLNAF FSAGGKGANV TVPFKEEAFA
0071 RADELTERAA LAGAVNTLMR LEDGRLLGDN TDGVGLLSDL ERLSFIRPGL RILLIGAGGA SRGVLLPLLS
0141 LDCAVTITNR TVSRAEELAK LFAHTGSIQA LSMDELEGHE FDLIINATSS GISGDIPAIP SSLIHPGIYC
0211 YDMFYQKGKT PFLAWCEQRG SKRNADGLGM LVAQAAHAFL LWHGVLPDVE PVIKQLQEEL SA
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 gcggcgttcc cggttgtgcc tggtgaaacg
-070 ggggggcgtt taaatccttc agaaatccgc gatgccctga cgggtgaact gtttcgacag gggtaacata
0001 atggaaacct atgctgtttt tggtaatccg atagcccaca gcaaatcgcc attcattcat cagcaatttg
0071 ctcagcaact gaatattgaa catccctatg ggcgcgtgtt ggcacccatc aatgatttca tcaacacact
0141 gaacgctttc tttagtgctg gtggtaaagg tgcgaatgtg acggtgcctt ttaaagaaga ggcttttgcc
0211 agagcggatg agcttactga acgggcagcg ttggctggtg ctgttaatac cctcatgcgg ttagaagatg
0281 gacgcctgct gggtgacaat accgatggtg taggcttgtt aagcgatctg gaacgtctgt cttttatccg
0351 ccctggttta cgtattctgc ttatcggcgc tggtggagca tctcgcggcg tactactgcc actcctttcc
0421 ctggactgtg cggtgacaat aactaatcgg acggtatccc gcgcggaaga gttggctaaa ttgtttgcgc
0491 acactggcag tattcaggcg ttgagtatgg acgaactgga aggtcatgag tttgatctca ttattaatgc
0561 aacatccagt ggcatcagtg gtgatattcc ggcgatcccg tcatcgctca ttcatccagg catttattgc
0631 tatgacatgt tctatcagaa aggaaaaact ccttttctgg catggtgtga gcagcgaggc tcaaagcgta
0701 atgctgatgg tttaggaatg ctggtggcac aggcggctca tgcctttctt ctctggcacg gtgttctgcc
0771 tgacgtagaa ccagttataa agcaattgca ggaggaattg tccgcgtgaa tcaggccatc cagtttccgg
0841 acagggaaga gtgggacgag aataaaaaat gtgtatgttt tcccgctctc gtgaatggta tgcaactgac
0911 atgcgcgat
|
