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PEC Original Annotations
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|
Essentiality
|
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Class
|
essential
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References (PMID)
|
J Bacteriol. 1993;175(21):6881-9.
Organization and nucleotide sequences of the genes encoding the biotin carboxyl carrier protein and biotin carboxylase protein of Pseudomonas aeruginosa acetyl coenzyme A carboxylase.
Best EA, Knauf VC.
(
7693652
)
|
|
|
Deletion
|
OCL24,25-1
(D)
|
|
Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
accB
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Related strains
|
|
Strains Search
|
Search strains by gene name:
accB
Search strains by all related name:
accB b3255 ECK3242 fabE JW3223 o156
|
General information (Go to Linear View: )
|
|
Gene Name
|
accB
|
|
Alternative name
|
b3255,ECK3242,fabE,JW3223,o156
|
|
Location, Length
|
3,403,458 - 3,403,928
(
+
)
;
73.36
min
;
471
(bp) ,
156
(aa)
|
|
Product
|
acetyl CoA carboxylase, BCCP subunit
|
|
Operon Name
|
accBC
|
|
Note
|
acetylCoA carboxylase, BCCP subunit; carrier of biotin; GO_process: GO:0042966 - biotin carboxyl carrier protein biosynthetic process
|
|
Function
|
carrier; Biosynthesis of cofactors, carriers: biotin carboxyl carrier protein (BCCP)
|
|
Gene Ontology
|
GO:0003989
;
acetyl-CoA carboxylase activity ( accB )
GO:0006633
;
fatty acid biosynthetic process ( accB )
GO:0008610
;
lipid biosynthetic process ( accB )
GO:0009317
;
acetyl-CoA carboxylase complex ( accB )
GO:0009374
;
biotin binding ( accB )
|
|
PID
|
1789653
|
EC number
(KEGG Pathway)
|
|
|
Verified Protein Starts
(data
compiled from literature and appropriate citations are available from EcoGene)
|
|
EcoGene
|
accB
(
EG10275
)
|
|
Number of removed
|
0 aa cleaved
|
|
SWISS-PROT
(
Show details
)
|
Entry name(Acc.no)
|
BCCP_ECOLI
(
P02905
)
|
|
- Protein name
|
Biotin carboxyl carrier protein of acetyl-CoA carboxylase
|
|
- Synonyms
|
BCCP
|
|
- Gene name
|
OrderedLocusNames=b3255, c4011, z4615, ECs4127, SF3293, S3510;
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Homology Analysis
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BLAST
|
|
Bacteria
|
|
GTOP
|
accB
(
homologous genes of other bacterias
)
|
|
PDB
(database updated :
2007.02.20
)
|
|
PSI-BLAST
|
Chain , Structure Of The Apo-Biotin Carboxyl Carrier Protein
|
|
SWISS-PROT
(database updated :
2007.02.20
)
|
|
BLAST
|
Biotin carboxyl carrier protein of acetyl-CoA carboxylase (BCCP)
|
|
PSI-BLAST
|
Biotin carboxyl carrier protein of acetyl-CoA carboxylase (BCCP)
|
|
nr
(database updated :
2007.02.20
)
|
|
BLAST
|
COG0511: Biotin carboxyl carrier protein [Escherichia coli B7A]
|
|
Pfam 28.0
(database updated :
2015-05
)
|
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Pfam
|
|
|
PROSITE
|
|
PROSITE
|
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
MYRISTYL
BIOTIN
|
|
MMBR References
|
J Bacteriol. 1993;175:332-340
Growth rate regulation of Escherichia coli acetyl coenzyme A carboxylase, which catalyzes the first committed step of lipid biosynthesis.
Li, S.-J., and J. E. Cronan, Jr.
|
Microbiol. Rev. 1993;57:522-542
Regulation of fatty acid biosynthesis in Escherichia coli.
Magnuson, K., S. Jackowski, C. O. Rock, and J. E. Cronan, Jr.
|
Nucleic Acids Res. 1989;17(10):3982
Nucleotide sequence of the fabE gene and flanking regions containing a bent DNA sequence of Escherichia coli.
Muramatsu S, Mizuno T.
(
2660106
)
|
J Biol Chem. 1977;252:3934-3940
Amino acid sequence of Escherichia coli biotin carboxyl carrier protein (9100).
Sutton, M. R., R. R. Fall, A. M. Nervi, A. W. Alberts, P. R. Vagelos, and R. A. Bradshaw.
|
J Bacteriol. 1987;169(11):4935-40.
Mutant isolation and molecular cloning of mre genes, which determine cell shape, sensitivity to mecillinam, and amount of penicillin-binding proteins in Escherichia coli.
Wachi M, Doi M, Tamaki S, Park W, Nakajima-Iijima S, Matsuhashi M.
(
2822655
)
|
| Sequences |
Amino acid
FASTA format
|
0001 MDIRKIKKLI ELVEESGISE LEISEGEESV RISRAAPAAS FPVMQQAYAA PMMQQPAQSN AAAPATVPSM
0071 EAPAAAEISG HIVRSPMVGT FYRTPSPDAK AFIEVGQKVN VGDTLCIVEA MKMMNQIEAD KSGTVKAILV
0141 ESGQPVEFDE PLVVIE
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 GAATTTATCG CTATGCATAC AGCTGTCGGG
-070 GCATACGCTT TACAGACGGC GGTGAAACGC CTGTCACAAT CACACTAAAC AAAGAGTACG GAACCCACTC
0001 atggatattc gtaagattaa aaaactgatc gagctggttg aagaatcagg catctccgaa ctggaaattt
0071 ctgaaggcga agagtcagta cgcattagcc gtgcagctcc tgccgcaagt ttccctgtga tgcaacaagc
0141 ttacgctgca ccaatgatgc agcagccagc tcaatctaac gcagccgctc cggcgaccgt tccttccatg
0211 gaagcgccag cagcagcgga aatcagtggt cacatcgtac gttccccgat ggttggtact ttctaccgca
0281 ccccaagccc ggacgcaaaa gcgttcatcg aagtgggtca gaaagtcaac gtgggcgata ccctgtgcat
0351 cgttgaagcc atgaaaatga tgaaccagat cgaagcggac aaatccggta ccgtgaaagc aattctggtc
0421 gaaagtggac aaccggtaga atttgacgag ccgctggtcg tcatcgagta aCGAGGCGAA CATGCTGGAT
0491 AAAATTGTTA TTGCCAACCG CGGCGAGATT GCATTGCGTA TTCTTCGTGC CTGTAAAGAA CTGGGCATCA
0561 AGACTGTCGC T
|
