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PEC Original Annotations
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Essentiality
|
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Class
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non-essential
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References (PMID)
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Mol Microbiol. 1997;26(5):1013-21.
Expression of gpsA encoding biosynthetic sn-glycerol 3-phosphate dehydrogenase suppresses both the LB- phenotype of a secB null mutant and the cold-sensitive phenotype of a secG null mutant.
Shimizu H, Nishiyama K, Tokuda H.
(
9426138
)
|
|
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Deletion
|
OCL29,30-6 (AK4-11 / BK5-11)
(D)
,
OCL29-8
(D)
|
|
Related gene (W3110 PEC)
|
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Gene Search
|
Search MG1655 PEC by gene name:
secG
|
|
Related strains
|
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Strains Search
|
Search strains by gene name:
secG
Search strains by all related name:
secG b3175 ECK3164 JW3142 prlH
|
General information (Go to Linear View: )
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Gene Name
|
secG
|
|
Alternative name
|
b3175,ECK3164,JW3142,prlH
|
|
Location, Length
|
3,320,195 - 3,320,527
(
-
)
;
71.56
min
;
333
(bp) ,
110
(aa)
|
|
Product
|
preprotein translocase membrane subunit
|
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Operon Name
|
secG-leuU
|
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Note
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protein export - membrane protein; GO_component: GO:0009274 - peptidoglycan-based cell wall; GO_component: GO:0019866 - organelle inner membrane
|
|
Function
|
transport; Protein, peptide secretion
|
|
Gene Ontology
|
GO:0005886
;
plasma membrane ( secG )
GO:0006810
;
transport ( secG )
GO:0009306
;
protein secretion ( secG )
GO:0015031
;
protein transport ( secG )
GO:0015450
;
P-P-bond-hydrolysis-driven protein transmembrane transporter activity ( secG )
GO:0016020
;
membrane ( secG )
GO:0016021
;
integral to membrane ( secG )
GO:0065002
;
intracellular protein transport across a membrane ( secG )
|
|
PID
|
1789565
|
EC number
(KEGG Pathway)
|
|
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SWISS-PROT
(
Show details
)
|
Entry name(Acc.no)
|
SECG_ECOLI
(
P33582
)
|
|
- Protein name
|
Protein-export membrane protein secG
|
|
- Synonyms
|
Preprotein translocase band 1 subunit, P12
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- Gene name
|
Name=secG; OrderedLocusNames=b3175, c3931, z4537, ECs4054;
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MMBR References
|
J Biol Chem. 1995;270:20106-20111
SecYEG and SecA are the stoichiometric components of preprotein translocase.
Douville, K., A. Price, J. Eichler, A. Economou, and W. Wickner.
|
FEBS Lett. 1996;381(1-2):25-8.
SecG plays a critical role in protein translocation in the absence of the proton motive force as well as at low temperature.
Hanada M, Nishiyama K, Tokuda H.
(
8641431
)
|
EMBO J. 1994;13:3272-3277
Disruption of the gene encoding p12 (SecG) reveals the direct involvement and important function of SecG in the protein translocation of Escherichia coli at low temperature.
Nishiyama, K., M. Hanada, and H. Tokuda.
|
EMBO J. 1993;12:3409-3415
A novel membrane protein involved in protein translocation across the cytoplasmic membrane of Escherichia coli.
Nishiyama, K., S. Mizushima, and H. Tokuda.
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EMBO J. 1995;14:4412-4421
A new genetic selection identifies essential residues in SecG, a component of the Escherichia coli protein export machinery.
Bost, S., and D. Belin.
|
J Biol Chem. 1997;272:4087-4093
prl mutations in the Escherichia coli secG gene.
Bost, S., and D. Belin.
|
J Biol Chem. 1996;271:29514-29516
Escherichia coli preprotein translocase.
Wickner, W., and M. R. Leonard.
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| Sequences |
Amino acid
FASTA format
|
0001 MYEALLVVFL IVAIGLVGLI MLQQGKGADM GASFGAGASA TLFGSSGSGN FMTRMTALLA TLFFIISLVL
0071 GNINSNKTNK GSEWENLSAP AKTEQTQPAA PAKPTSDIPN
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 tggttagtat tcacacccgc ttcagtggga
-070 aagattaaaa actcccgctt tattggttga agcattggta cgcggcaact ccgcaaggaa caggttgatt
0001 atgtatgaag ctcttttagt agttttcctt attgtggcaa ttggccttgt tggtctgatc atgctgcagc
0071 aaggtaaagg cgctgatatg ggagcctcct tcggagcagg cgcttccgct acgctgtttg gttcaagtgg
0141 ttctggtaac ttcatgaccc gcatgacggc gctgctggca acgttattct tcatcatcag tctggtgctg
0211 ggtaacatca atagcaacaa aaccaataaa ggtagcgaat gggaaaatct gagtgcaccg gcgaaaaccg
0281 aacaaactca gccagctgct ccggctaagc cgaccagcga tatcccgaac taaaaagtag tatccgtgcc
0351 gaggtggtgg aattggtaga cacgctacct tgaggtggta gtgcccaata gggcttacgg gttcaagtcc
0421 cgtcctcggt acc
|
