|
PEC Original Annotations
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|
Essentiality
|
|
Class
|
non-essential
|
|
References (PMID)
|
|
|
Deletion
|
5
(LD)
,
OCL32
(D)
,
OCL32,34-1 (LD 5-1'_CRS)
(D)
,
OCL32,34-2 (LD 5-1'_P/O)
(D)
|
|
Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
tdcD
|
|
Related strains
|
|
Strains Search
|
Search strains by gene name:
tdcD
Search strains by all related name:
tdcD b3115 ECK3104 f406 JW5806 yhaA
|
General information (Go to Linear View: )
|
|
Gene Name
|
tdcD
|
|
Alternative name
|
b3115,ECK3104,f406,JW5806,yhaA
|
|
Location, Length
|
3,260,474 - 3,261,682
(
-
)
;
70.27
min
;
1209
(bp) ,
402
(aa)
|
|
Product
|
propionate kinase/acetate kinase C, anaerobic
|
|
Operon Name
|
tdcABCDEFG
|
|
Note
|
propionate kinase/acetate kinase II, anaerobic; GO_process: GO:0009063 - cellular amino acid catabolic process
|
|
Function
|
putative enzyme; Not classified,1.1.3 metabolism; carbon utilization; amino acids,1.7.30 metabolism; central intermediary metabolism; threonine catabolism
|
|
Gene Ontology
|
GO:0005515
;
protein binding ( tdcD )
GO:0005622
;
intracellular ( tdcD )
GO:0006082
;
organic acid metabolic process ( tdcD )
GO:0008152
;
metabolic process ( tdcD )
GO:0008776
;
acetate kinase activity ( tdcD )
GO:0008980
;
propionate kinase activity ( tdcD )
GO:0016301
;
kinase activity ( tdcD )
GO:0016310
;
phosphorylation ( tdcD )
GO:0016740
;
transferase activity ( tdcD )
GO:0016774
;
phosphotransferase activity, carboxyl group as acceptor ( tdcD )
|
|
PID
|
145693184
|
EC number
(KEGG Pathway)
|
2.7.2.15
|
|
SWISS-PROT
(
Show details
[
3
more]
)
|
Entry name(Acc.no)
|
TDCD_ECOLI
(
P11868
;
P76666
)
|
|
- Protein name
|
Propionate kinase
|
|
- Synonyms
|
EC 2.7.2.-
|
|
- Gene name
|
Name=tdcD; OrderedLocusNames=b3115;
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Homology Analysis
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BLAST
|
|
Bacteria
|
|
GTOP
|
tdcD
(
homologous genes of other bacterias
)
|
|
PDB
(database updated :
2007.02.20
)
|
|
PSI-BLAST
|
Chain A, Crystal Structure Of Adp Bound Propionate Kinase (Tdcd) From Salmonella Typhimurium
|
|
SWISS-PROT
(database updated :
2007.02.20
)
|
|
BLAST
|
Propionate kinase
|
|
PSI-BLAST
|
Propionate kinase
|
|
nr
(database updated :
2007.02.20
)
|
|
BLAST
|
propionate kinase/acetate kinase C, anaerobic [Escherichia coli K12]
|
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Pfam 28.0
(database updated :
2015-05
)
|
|
Pfam
|
|
|
PROSITE
|
|
PROSITE
|
ASN_GLYCOSYLATION
CAMP_PHOSPHO_SITE
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
MYRISTYL
ACETATE_KINASE_1
ACETATE_KINASE_2
|
|
MMBR References
|
Mol Microbiol. 1998;27(2):477-92.
Novel keto acid formate-lyase and propionate kinase enzymes are components of an anaerobic pathway in Escherichia coli that degrades L-threonine to propionate.
Hesslinger C, Fairhurst SA, Sawers G.
(
9484901
)
|
Nucleic Acids Res. 1989;17(10):3994
The complete nucleotide sequence of the tdc region of Escherichia coli.
Schweizer HP, Datta P.
(
2660107
)
|
| Sequences |
Amino acid
FASTA format
|
0001 MNEFPVVLVI NCGSSSIKFS VLDASDCEVL MSGIADGINS ENAFLSVNGG EPAPLAHHSY EGALKAIAFE
0071 LEKRNLNDSV ALIGHRIAHG GSIFTESAII TDEVIDNIRR VSPLAPLHNY ANLSGIESAQ QLFPGVTQVA
0141 VFDTSFHQTM APEAYLYGLP WKYYEELGVR RYGFHGTSHR YVSQRAHSLL NLAEDDSGLV VAHLGNGASI
0211 CAVRNGQSVD TSMGMTPLEG LMMGTRSGDV DFGAMSWVAS QTNQSLGDLE RVVNKESGLL GISGLSSDLR
0281 VLEKAWHEGH ERAQLAIKTF VHRIARHIAG HAASLRRLDG IIFTGGIGEN SSLIRRLVME HLAVLGLEID
0351 TEMNNRSNSC GERIVSSENA RVICAVIPTN EEKMIALDAI HLGKVNAPAE FA
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 ggtcgtctgg ataacgtgtt tgttaccgtg
-070 attggtctgc tgaccatcct gaacatcgta tacaaactgt tttaatccgt aactcaggat gagaaaagag
0001 atgaatgaat ttccggttgt tttggttatt aactgtggtt cgtcttcgat taagttttcc gtgctcgatg
0071 ccagcgactg tgaagtatta atgtcaggta ttgccgacgg tattaactcg gaaaatgcat tcttatccgt
0141 aaatggggga gagccagcac cgctggctca ccacagctac gaaggtgcat tgaaggcaat tgcatttgaa
0211 ctggaaaaac ggaatttaaa tgacagtgtg gccttaattg gccaccgcat cgctcacggc ggcagtattt
0281 ttaccgagtc cgccattatt accgatgaag tcattgataa tatccgtcgc gtttctccac tggcacccct
0351 gcataattac gccaatttaa gtggtattga atcggcgcag caattatttc cgggcgtaac tcaggtggcg
0421 gtatttgata ccagtttcca ccagacgatg gctccggaag cttatttata cggcctgccg tggaaatatt
0491 atgaagagtt aggtgtacgc cgttatggtt tccacggcac gtcgcaccgc tatgtttccc agcgcgcaca
0561 ttcgctgctg aatctggcgg aagatgactc cggcctggtt gtggcgcatc ttggcaatgg cgcgtcaatc
0631 tgcgcggttc gcaacggtca gagtgttgat acctcaatgg gaatgacgcc gctggaaggc ttgatgatgg
0701 gtacccgcag tggcgatgtc gactttggtg cgatgtcctg ggtcgccagc caaaccaacc agagcctggg
0771 tgacctggaa cgcgtagtga ataaagagtc gggattatta ggtatttccg gtctttcttc ggatttacgt
0841 gttctggaaa aagcctggca tgaaggtcac gaacgcgcgc aactggcaat taaaaccttt gttcaccgaa
0911 ttgcccgtca tattgccgga cacgcagctt cattacgtcg cctggatgga attatattca ccggcggaat
0981 aggagagaat tcaagcttaa ttcgtcgtct ggtcatggaa catttggctg tattaggctt agagattgat
1051 acagaaatga ataatcgctc taactcctgt ggtgagcgaa ttgtttccag tgaaaatgcg cgtgtcattt
1121 gtgccgttat tccgactaac gaagaaaaaa tgattgcttt ggatgccatt catttaggca aagttaacgc
1191 gcccgcagaa tttgcataat ttagttgaag tattgtagag agattatttt tcatgaaggt agatattgat
1261 accagcgata agctgtacgc cgacgcatgg cttggcttta aaggtacgg
|
