MG1655
W3110
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Gene Report : tdcG
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
     Deletion 5 (LD)  ,  OCL32 (D)  ,  OCL32,34-1 (LD 5-1'_CRS) (D)  ,  OCL32,34-2 (LD 5-1'_P/O) (D)  
Related gene (W3110 PEC)
     Gene Search Search MG1655 PEC by gene name:  tdcG
Related strains
     Strains Search Search strains by gene name:  tdcG   Search strains by all related name:  tdcG b3111 b3112 b4471 ECK3101 f140 f275 JW5520 sdhY yhaP yhaQ

General information  (Go to Linear View:)
 Gene Name tdcG  
 Alternative name b3111,b3112,b4471,ECK3101,f140,f275,JW5520,sdhY,yhaP,yhaQ  
 Location, Length 3,256,307 - 3,257,671 (  -  ) ;   70.18 min ; 1365 (bp) ,   454 (aa) Go to Linear View
 Product L-serine dehydratase 3  
 Operon Name tdcABCDEFG  
 Note L-serine dehydratase; GO_process: GO:0009063 - cellular amino acid catabolic process  
 Function 1.1.3 metabolism; carbon utilization; amino acids  
 Gene Ontology GO:0003941 ; L-serine ammonia-lyase activity ( tdcG )
GO:0005506 ; iron ion binding ( tdcG )
GO:0006094 ; gluconeogenesis ( tdcG )
GO:0016829 ; lyase activity ( tdcG )
GO:0046872 ; metal ion binding ( tdcG )
GO:0051536 ; iron-sulfur cluster binding ( tdcG )
GO:0051539 ; 4 iron, 4 sulfur cluster binding ( tdcG )
 PID 48994925  
 EC number
  (KEGG Pathway)   		4.3.1.17  
SWISS-PROT  ( Show details )
  botton Entry name(Acc.no) TDCG_ECOLI ( P42630 ; P42629 )
    -  Protein name L-serine dehydratase tdcG  
    -  Synonyms EC 4.3.1.17, L-serine deaminase, SDH  
    -  Gene name Name=tdcG; OrderedLocusNames=b3111/b3112;  

 Linear View (Whole Mode)
View Location
   3245.0  –  3270.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP tdcG (  homologous genes of other bacterias  )  
    PDB     (database updated : 2007.02.20 )
         PSI-BLAST Chain A, The Crystal Structure Of Iron, Sulfur-Dependent L-Serine Dehydratase From Legionella Pneumophila Subsp. Pneumophila  
    SWISS-PROT     (database updated : 2007.02.20 )
         BLAST L-serine dehydratase tdcG  
         PSI-BLAST L-serine dehydratase 1
    nr     (database updated : 2007.02.20 )
         BLAST L-serine dehydratase 3 [Escherichia coli K12]  
Pfam 28.0   (database updated : 2015-05 )
    Pfam
PROSITE
    PROSITE ASN_GLYCOSYLATION    CAMP_PHOSPHO_SITE    PKC_PHOSPHO_SITE    CK2_PHOSPHO_SITE    TYR_PHOSPHO_SITE    MYRISTYL    ATP_GTP_A     

Other Cross-Reference
    COG COG1760E 
    EcoCyc tdcG 

MMBR References
Mol Microbiol. 1998;27(2):477-92.
Novel keto acid formate-lyase and propionate kinase enzymes are components of an anaerobic pathway in Escherichia coli that degrades L-threonine to propionate.
Hesslinger C, Fairhurst SA, Sawers G. ( 9484901 )
Nucleic Acids Res. 1989;17(10):3994
The complete nucleotide sequence of the tdc region of Escherichia coli.
Schweizer HP, Datta P. ( 2660107 )

Sequences
Amino acid
FASTA format 
0001 MISAFDIFKI GIGPSSSHTV GPMNAGKSFI DRLESSGLLT ATSHIVVDLY GSLSLTGKGH ATDVAIIMGL 
0071 AGNSPQDVVI DEIPAFIELV TRSGRLPVAS GAHIVDFPVA KNIIFHPEML PRHENGMRIT AWKGQEELLS 
0141 KTYYSVGGGF IVEEEHFGLS HDVETSVPYD FHSAGELLKM CDYNGLSISG LMMHNELALR SKAEIDAGFA 
0211 RIWQVMHDGI ERGMNTEGVL PGPLNVPRRA VALRRQLVSS DNISNDPMNV IDWINMYALA VSEENAAGGR 
0281 VVTAPTNGAC GIIPAVLAYY DKFRRPVNER SIARYFLAAG AIGALYKMNA SISGAEVGCQ GEIGVACSMA 
0351 AAGLTELLGG SPAQVCNAAE IAMEHNLGLT CDPVAGQVQI PCIERNAINA VKAVNAARMA MRRTSAPRVS 
0421 LDKVIETMYE TGKDMNDKYR ETSRGGLAIK VVCG
Nucleotide
FASTA format

View sequence out neighbor 100bp 
-100                                             ttgaagccat cgcagtacgt agtgcgtaaa 
-070 gcctcgtgag cgggacggtc gtaaggtcgt tccgctccac ttcactgaac ggcaatccga gggtgtggat 
0001 atgattagtg cattcgatat tttcaaaatt gggattggtc cctccagttc gcataccgtg gggccaatga 
0071 atgccggaaa aagttttatt gatcggctgg aaagtagcgg cttattaacc gcgacgagcc atattgtggt 
0141 cgatctgtac gggtcgttgt cactgacggg caaaggccat gccacggatg tcgccatcat catgggactg 
0211 gcaggaaaca gtccgcagga tgttgtcatt gatgagatcc ctgcatttat agagttagta acgcgcagcg 
0281 ggcggctgcc agtggcatct ggtgcgcata ttgttgattt tcctgtagca aagaacatta tcttccatcc 
0351 cgaaatgttg cctcgccatg agaacggaat gcggatcact gcctggaagg gacaggaaga gctattaagt 
0421 aaaacctatt actctgtcgg cggcgggttt attgtcgaag aagaacactt cggcctgtcg cacgatgtcg 
0491 aaacgtccgt accttacgat ttccactcag caggtgaact gctgaaaatg tgtgattaca acggcctgtc 
0561 tatatctggt ctgatgatgc acaacgagct agcgctgcgc agcaaagcgg aaattgacgc cggttttgcc 
0631 cgtatctggc aagtgatgca tgacggtatt gaacgtggga tgaacactga aggcgtgctg cctggtccgc 
0701 tcaatgtgcc gcgccgtgcc gtagcgctgc gtcgtcagct ggtttccagc gataacatct ctaacgatcc 
0771 gatgaatgtc atcgactgga tcaacatgta cgcgctggcg gttagtgaag aaaacgcagc tggcgggcgc 
0841 gtggtaacgg caccgactaa cggtgcgtgc ggcattattc cggcagtact ggcttattac gataagttcc 
0911 gtcgtccggt aaacgagcgg tcaattgccc gctattttct ggccgcgggg gctattggcg cgctgtataa 
0981 aatgaacgcc tccatctctg gcgcggaagt cggctgtcag ggggagattg gcgtggcctg ttcaatggcg 
1051 gcggcagggt taactgaact actgggcggc agtccggcgc aggtatgcaa tgcggcggaa atcgcgatgg 
1121 agcataacct tgggctgacc tgcgatccgg ttgccggaca ggtacaaatc ccgtgcattg aacgtaatgc 
1191 cattaatgcc gtgaaagcag taaacgccgc gcggatggcg atgcgccgca cctcggcacc gcgtgtttca 
1261 ctcgataaag tgatcgagac gatgtatgaa accggcaaag atatgaacga taaataccgc gaaacatcac 
1331 gcggaggact ggccattaaa gtggtctgcg gctgacattg ctgtcagctt tcatccttgg gtgcacaaat 
1401 gtgcaccttt tttttgtgat ctgccgcaaa tagagaatga atattctcct gcgattaatt tagta