|
PEC Original Annotations
|
|
Essentiality
|
|
Class
|
non-essential
|
|
References (PMID)
|
Gene. 1995;158(1):9-14.
Gene disruption in Escherichia coli: TcR and KmR cassettes with the option of Flp-catalyzed excision of the antibiotic-resistance determinant.
Cherepanov PP, Wackernagel W.
(
7789817
)
|
|
|
Deletion
|
OCL39
(D)
,
OCL39-10-2
(D)
|
|
Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
endA
|
|
Related strains
|
|
Strains Search
|
Search strains by gene name:
endA
Search strains by all related name:
endA b2945 ECK2940 JW2912
|
General information (Go to Linear View: )
|
|
Gene Name
|
endA
|
|
Alternative name
|
b2945,ECK2940,JW2912
|
|
Location, Length
|
3,088,369 - 3,089,076
(
+
)
;
66.56
min
;
708
(bp) ,
235
(aa)
|
|
Product
|
DNA-specific endonuclease I
|
|
Operon Name
|
endA
|
|
Note
|
GO_process: GO:0006308 - DNA catabolic process
|
|
Function
|
enzyme; Degradation of DNA
|
|
Gene Ontology
|
GO:0004518
;
nuclease activity ( endA )
GO:0004519
;
endonuclease activity ( endA )
GO:0004530
;
deoxyribonuclease I activity ( endA )
GO:0016787
;
hydrolase activity ( endA )
GO:0042597
;
periplasmic space ( endA )
|
|
PID
|
1789314
|
EC number
(KEGG Pathway)
|
3.1.21.1
|
|
SWISS-PROT
(
Show details
[
2
more]
)
|
Entry name(Acc.no)
|
END1_ECOLI
(
P25736
)
|
|
- Protein name
|
Endonuclease I precursor
|
|
- Synonyms
|
EC 3.1.21.1, Endo I
|
|
- Gene name
|
Name=endA; OrderedLocusNames=b2945;
|
|
Homology Analysis
|
|
BLAST
|
|
Bacteria
|
|
GTOP
|
endA
(
homologous genes of other bacterias
)
|
|
PDB
(database updated :
2007.02.20
)
|
|
PSI-BLAST
|
Chain A, The 1.6 A Crystal Structure Of Vibrio Cholerae Extracellular Endonuclease I
|
|
SWISS-PROT
(database updated :
2007.02.20
)
|
|
BLAST
|
Endonuclease-1 precursor
|
|
PSI-BLAST
|
Nuclease nucM precursor
|
|
nr
(database updated :
2007.02.20
)
|
|
BLAST
|
DNA-specific endonuclease I [Escherichia coli K12]
|
|
Pfam 28.0
(database updated :
2015-05
)
|
|
Pfam
|
|
|
PROSITE
|
|
PROSITE
|
ASN_GLYCOSYLATION
CK2_PHOSPHO_SITE
MYRISTYL
AMIDATION
PEROXIDASE_1
|
|
MMBR References
|
J Bacteriol. 1994;176(5):1550-1.
Location of the endA gene coding for endonuclease I on the physical map of the Escherichia coli K-12 chromosome.
Jekel M, Wackernagel W.
(
8113204
)
|
J Bacteriol. 1971;107(1):87-94.
Mutants of Escherichia coli lacking endonuclease I, ribonuclease I, or ribonuclease II.
Wright M.
(
4105037
)
|
| Sequences |
Amino acid
FASTA format
|
0001 MYRYLSIAAV VLSAAFSGPA LAEGINSFSQ AKAAAVKVHA DAPGTFYCGC KINWQGKKGV VDLQSCGYQV
0071 RKNENRASRV EWEHVVPAWQ FGHQRQCWQD GGRKNCAKDP VYRKMESDMH NLQPSVGEVN GDRGNFMYSQ
0141 WNGGEGQYGQ CAMKVDFKEK AAEPPARARG AIARTYFYMR DQYNLTLSRQ QTQLFNAWNK MYPVTDWECE
0211 RDERIAKVQG NHNPYVQRAC QARKS
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 AAATAACCAT CTGAACTATC AGGAACTTTC
-070 CTGATCTGGC TGATTGCATA CCAAAACAGC TTTCGCTACG TTGCTGGCTC GTTTTAACAC GGAGTAAGTG
0001 atgtaccgtt atttgtctat tgctgcggtg gtactgagcg cagcattttc cggcccggcg ttggccgaag
0071 gtatcaatag tttttctcag gcgaaagccg cggcggtaaa agtccacgct gacgcgcccg gtacgtttta
0141 ttgcggatgt aaaattaact ggcagggcaa aaaaggcgtt gttgatctgc aatcgtgcgg ctatcaggtg
0211 cgcaaaaatg aaaaccgcgc cagccgcgta gagtgggaac atgtcgttcc cgcctggcag ttcggtcacc
0281 agcgccagtg ctggcaggac ggtggacgta aaaactgcgc taaagatccg gtctatcgca agatggaaag
0351 cgatatgcat aacctgcagc cgtcagtcgg tgaggtgaat ggcgatcgcg gcaactttat gtacagccag
0421 tggaatggcg gtgaaggcca gtacggtcaa tgcgccatga aggtcgattt caaagaaaaa gctgccgaac
0491 caccagcgcg tgcacgcggt gccattgcgc gcacctactt ctatatgcgc gaccaataca acctgacact
0561 ctctcgccag caaacgcagc tgttcaacgc atggaacaag atgtatccgg ttaccgactg ggagtgcgag
0631 cgcgatgaac gcatcgcgaa ggtgcagggc aatcataacc cgtatgtgca acgcgcttgc caggcgcgaa
0701 agagctaaCC TACACTAGCG GGATTCTTTT TGTTAACCCC TACCCCACGC GTACAACCGC GTGGGGAGAC
0771 GACGCGGATT TTTAACTATG CGTATCCCCC GCATTTAT
|
