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PEC Original Annotations
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|
Essentiality
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Class
|
non-essential
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|
References (PMID)
|
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
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Deletion
|
OCL40
(D)
|
|
Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
scpA
|
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Related strains
|
|
Strains Search
|
Search strains by gene name:
scpA
Search strains by all related name:
scpA b2917 ECK2913 JW2884 mcm sbm yliK
|
General information (Go to Linear View: )
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|
Gene Name
|
scpA
|
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Alternative name
|
b2917,ECK2913,JW2884,mcm,sbm,yliK
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|
Location, Length
|
3,058,872 - 3,061,016
(
+
)
;
65.93
min
;
2145
(bp) ,
714
(aa)
|
|
Product
|
methylmalonyl-CoA mutase
|
|
Operon Name
|
scpA-argK-scpBC
|
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Note
|
methylmalonyl-CoA mutase (MCM); GO_process: GO:0019395 - fatty acid oxidation
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Function
|
enzyme; Degradation of small molecules: Fatty acids
|
|
Gene Ontology
|
GO:0003824
;
catalytic activity ( sbm )
GO:0004494
;
methylmalonyl-CoA mutase activity ( sbm )
GO:0008152
;
metabolic process ( sbm )
GO:0016853
;
isomerase activity ( sbm )
GO:0016866
;
intramolecular transferase activity ( sbm )
GO:0031419
;
cobalamin binding ( sbm )
GO:0046872
;
metal ion binding ( sbm )
GO:0050897
;
cobalt ion binding ( sbm )
|
|
PID
|
1789284
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EC number
(KEGG Pathway)
|
5.4.99.2
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SWISS-PROT
(
Show details
[
1
more]
)
|
Entry name(Acc.no)
|
SBM_ECOLI
(
P27253
)
|
|
- Protein name
|
Sbm protein.
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- Synonyms
|
|
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- Gene name
|
Name=sbm; OrderedLocusNames=b2917;
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Homology Analysis
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BLAST
|
|
Bacteria
|
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GTOP
|
yliK
(
homologous genes of other bacterias
)
|
|
PDB
(database updated :
2007.02.20
)
|
|
PSI-BLAST
|
Chain A, Methylmalonyl-Coa Mutase
|
|
SWISS-PROT
(database updated :
2007.02.20
)
|
|
BLAST
|
Sbm protein
|
|
PSI-BLAST
|
Methylmalonyl-CoA mutase, mitochondrial precursor
|
|
nr
(database updated :
2007.02.20
)
|
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BLAST
|
methylmalonyl-CoA mutase [Escherichia coli K12]
|
|
Pfam 28.0
(database updated :
2015-05
)
|
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Pfam
|
|
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PROSITE
|
|
PROSITE
|
GLYCOSAMINOGLYCAN
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
MYRISTYL
AMIDATION
METMALONYL_COA_MUTASE
|
| Sequences |
Amino acid
FASTA format
|
0001 MSNVQEWQQL ANKELSRREK TVDSLVHQTA EGIAIKPLYT EADLDNLEVT GTLPGLPPYV RGPRATMYTA
0071 QPWTIRQYAG FSTAKESNAF YRRNLAAGQK GLSVAFDLAT HRGYDSDNPR VAGDVGKAGV AIDTVEDMKV
0141 LFDQIPLDKM SVSMTMNGAV LPVLAFYIVA AEEQGVTPDK LTGTIQNDIL KEYLCRNTYI YPPKPSMRII
0211 ADIIAWCSGN MPRFNTISIS GYHMGEAGAN CVQQVAFTLA DGIEYIKAAI SAGLKIDDFA PRLSFFFGIG
0281 MDLFMNVAML RAARYLWSEA VSGFGAQDPK SLALRTHCQT SGWSLTEQDP YNNVIRTTIE ALAATLGGTQ
0351 SLHTNAFDEA LGLPTDFSAR IARNTQIIIQ EESELCRTVD PLAGSYYIES LTDQIVKQAR AIIQQIDEAG
0421 GMAKAIEAGL PKRMIEEASA REQSLIDQGK RVIVGVNKYK LDHEDETDVL EIDNVMVRNE QIASLERIRA
0491 TRDDAAVTAA LNALTHAAQH NENLLAAAVN AARVRATLGE ISDALEVAFD RYLVPSQCVT GVIAQSYHQS
0561 EKSASEFDAI VAQTEQFLAD NGRRPRILIA KMGQDGHDRG AKVIASAYSD LGFDVDLSPM FSTPEEIARL
0631 AVENDVHVVG ASSLAAGHKT LIPELVEALK KWGREDICVV AGGVIPPQDY AFLQERGVAA IYGPGTPMLD
0701 SVRDVLNLIS QHHD
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 CGACGTCTGA ATGCATTTTT TTTGCTGGCG
-070 ACAAACCCAC GTAAAAAGCT CACCGTAGGC GCAAATACCC TCATTTTGAT TGCGTTTTAC GGAGCAAATA
0001 atgtctaacg tgcaggagtg gcaacagctt gccaacaagg aattgagccg tcgggagaaa actgtcgact
0071 cgctggttca tcaaaccgcg gaagggatcg ccatcaagcc gctgtatacc gaagccgatc tcgataatct
0141 ggaggtgaca ggtacccttc ctggtttgcc gccctacgtt cgtggcccgc gtgccactat gtataccgcc
0211 caaccgtgga ccatccgtca gtatgctggt ttttcaacag caaaagagtc caacgctttt tatcgccgta
0281 acctggccgc cgggcaaaaa ggtctttccg ttgcgtttga ccttgccacc caccgtggct acgactccga
0351 taacccgcgc gtggcgggcg acgtcggcaa agcgggcgtc gctatcgaca ccgtggaaga tatgaaagtc
0421 ctgttcgacc agatcccgct ggataaaatg tcggtttcga tgaccatgaa tggcgcagtg ctaccagtac
0491 tggcgtttta tatcgtcgcc gcagaagagc aaggtgttac acctgataaa ctgaccggca ccattcaaaa
0561 cgatattctc aaagagtacc tctgccgcaa cacctatatt tacccaccaa aaccgtcaat gcgcattatc
0631 gccgacatca tcgcctggtg ttccggcaac atgccgcgat ttaataccat cagtatcagc ggttaccaca
0701 tgggtgaagc gggtgccaac tgcgtgcagc aggtagcatt tacgctcgct gatgggattg agtacatcaa
0771 agcagcaatc tctgccggac tgaaaattga tgacttcgct cctcgcctgt cgttcttctt cggcatcggc
0841 atggatctgt ttatgaacgt cgccatgttg cgtgcggcac gttatttatg gagcgaagcg gtcagtggat
0911 ttggcgcaca ggacccgaaa tcactggcgc tgcgtaccca ctgccagacc tcaggctgga gcctgactga
0981 acaggatccg tataacaacg ttatccgcac caccattgaa gcgctggctg cgacgctggg cggtactcag
1051 tcactgcata ccaacgcctt tgacgaagcg cttggtttgc ctaccgattt ctcagcacgc attgcccgca
1121 acacccagat catcatccag gaagaatcag aactctgccg caccgtcgat ccactggccg gatcctatta
1191 cattgagtcg ctgaccgatc aaatcgtcaa acaagccaga gctattatcc aacagatcga cgaagccggt
1261 ggcatggcga aagcgatcga agcaggtctg ccaaaacgaa tgatcgaaga ggcctcagcg cgcgaacagt
1331 cgctgatcga ccagggcaag cgtgtcatcg ttggtgtcaa caagtacaaa ctggatcacg aagacgaaac
1401 cgatgtactt gagatcgaca acgtgatggt gcgtaacgag caaattgctt cgctggaacg cattcgcgcc
1471 acccgtgatg atgccgccgt aaccgccgcg ttgaacgccc tgactcacgc cgcacagcat aacgaaaacc
1541 tgctggctgc cgctgttaat gccgctcgcg ttcgcgccac cctgggtgaa atttccgatg cgctggaagt
1611 cgctttcgac cgttatctgg tgccaagcca gtgtgttacc ggcgtgattg cgcaaagcta tcatcagtct
1681 gagaaatcgg cctccgagtt cgatgccatt gttgcgcaaa cggagcagtt ccttgccgac aatggtcgtc
1751 gcccgcgcat tctgatcgct aagatgggcc aggatggaca cgatcgcggc gcgaaagtga tcgccagcgc
1821 ctattccgat ctcggtttcg acgtagattt aagcccgatg ttctctacac ctgaagagat cgcccgcctg
1891 gccgtagaaa acgacgttca cgtagtgggc gcatcctcac tggctgccgg tcataaaacg ctgatcccgg
1961 aactggtcga agcgctgaaa aaatggggac gcgaagatat ctgcgtggtc gcgggtggcg tcattccgcc
2031 gcaggattac gccttcctgc aagagcgcgg cgtggcggcg atttatggtc caggtacacc tatgctcgac
2101 agtgtgcgcg acgtactgaa tctgataagc cagcatcatg attaaTGAAG CCACGCTGGC AGAAAGTATT
2171 CGCCGCTTAC GTCAGGGTGA GCGTGCCACA CTCGCCCAGG CCATGACGCT GGTGGAAAGC CGTCACCCGC
2241 GTCAT
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