MG1655
W3110
Search for
Japanese | English
Top Genes Deletions Circular Linear Motif Contigs Reference SequenceCutter Download Strains TEC
Gene Report : aas
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)
J Biol Chem. 1991;266(21):13783-8.
Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity.
Hsu L, Jackowski S, Rock CO. ( 1649829 )
     Deletion OCL44 (D)  
Related gene (W3110 PEC)
     Gene Search Search MG1655 PEC by gene name:  aas
Related strains
     Strains Search Search strains by gene name:  aas   Search strains by all related name:  aas b2836 ECK2832 JW2804

General information  (Go to Linear View:)
 Gene Name aas  
 Alternative name b2836,ECK2832,JW2804  
 Location, Length 2,971,877 - 2,974,036 (  -  ) ;   64.05 min ; 2160 (bp) ,   719 (aa) Go to Linear View
 Product fused 2-acylglycerophospho-ethanolamine acyltransferase/acyl-acyl carrier protein synthetase  
 Operon Name aas-lplT  
 Note 2-acyl-glycerophospho-ethanolamine acyltransferase; acyl-acyl-carrier protein synthetase; GO_component: GO:0009274 - peptidoglycan-based cell wall; GO_component: GO:0019866 - organelle inner membrane; GO_process: GO:0006464 - protein modification process  
 Function enzyme; Fatty acid and phosphatidic acid biosynthesis  
 Gene Ontology GO:0000166 ; nucleotide binding ( aas )
GO:0003824 ; catalytic activity ( aas )
GO:0005524 ; ATP binding ( aas )
GO:0005886 ; plasma membrane ( aas )
GO:0008152 ; metabolic process ( aas )
GO:0008415 ; acyltransferase activity ( aas )
GO:0008779 ; acyl-[acyl-carrier-protein]-phospholipid O-acyltransferase activity ( aas )
GO:0008922 ; long-chain-fatty-acid-[acyl-carrier-protein] ligase activity ( aas )
GO:0016020 ; membrane ( aas )
GO:0016021 ; integral to membrane ( aas )
GO:0016740 ; transferase activity ( aas )
GO:0016874 ; ligase activity ( aas )
 PID 1789201  
 EC number
  (KEGG Pathway)   		2.3.1.40   6.2.1.20  
SWISS-PROT  ( Show details [ 2 more] )
  botton Entry name(Acc.no) AAS_ECOLI ( P31119 ; Q46935 )
    -  Protein name AAS bifunctional protein  
    -  Synonyms  
    -  Gene name Name=aas; OrderedLocusNames=b2836;  

 Linear View (Whole Mode)
View Location
   2960.0  –  2985.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP aas (  homologous genes of other bacterias  )  
    PDB     (database updated : 2007.02.20 )
         PSI-BLAST Chain A, Crystal Structure Of The Thermostable Japanese Firefly Luciferase Complexed With High-Energy Intermediate Analogue  
    SWISS-PROT     (database updated : 2007.02.20 )
         BLAST AAS bifunctional protein [Includes: 2-acylglycerophosphoethanolamine acyltransferase  
         PSI-BLAST AAS bifunctional protein [Includes: 2-acylglycerophosphoethanolamine acyltransferase
    nr     (database updated : 2007.02.20 )
         BLAST 2-acyl-glycerophospho-ethanolamine acyltransferase [Escherichia coli K12]  
Pfam 28.0   (database updated : 2015-05 )
    Pfam
PROSITE
    PROSITE ASN_GLYCOSYLATION    PKC_PHOSPHO_SITE    CK2_PHOSPHO_SITE    TYR_PHOSPHO_SITE    MYRISTYL    AMIDATION    AMP_BINDING     

Other Cross-Reference
    COG COG0204I  COG0318IQ 
    EcoCyc aas 

MMBR References
J Biol Chem. 1991;266:13783-13788
Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity.
Hsu, L., S. Jackowski, and C. O. Rock.
J Biol Chem. 1994;269:2921-2928
Sequence and function of the aas gene in Escherichia coli.
Jackowski, S., P. D. Jackson, and C. O. Rock.

Sequences
Amino acid
FASTA format 
0001 MLFSFFRNLC RVLYRVRVTG DTQALKGERV LITPNHVSFI DGILLGLFLP VRPVFAVYTS ISQQWYMRWL 
0071 KSFIDFVPLD PTQPMAIKHL VRLVEQGRPV VIFPEGRITT TGSLMKIYDG AGFVAAKSGA TVIPVRIEGA 
0141 ELTHFSRLKG LVKRRLFPQI TLHILPPTQV AMPDAPRARD RRKIAGEMLH QIMMEARMAV RPRETLYESL 
0211 LSAMYRFGAG KKCVEDVNFT PDSYRKLLTK TLFVGRILEK YSVEGERIGL MLPNAGISAA VIFGAIARRR 
0281 MPAMMNYTAG VKGLTSAITA AEIKTIFTSR QFLDKGKLWH LPEQLTQVRW VYLEDLKADV TTADKVWIFA 
0351 HLLMPRLAQV KQQPEEEALI LFTSGSEGHP KGVVHSHKSI LANVEQIKTI ADFTTNDRFM SALPLFHSFG 
0421 LTVGLFTPLL TGAEVFLYPS PLHYRIVPEL VYDRSCTVLF GTSTFLGHYA RFANPYDFYR LRYVVAGAEK 
0491 LQESTKQLWQ DKFGLRILEG YGVTECAPVV SINVPMAAKP GTVGRILPGM DARLLSVPGI EEGGRLQLKG 
0561 PNIMNGYLRV EKPGVLEVPT AENVRGEMER GWYDTGDIVR FDEQGFVQIQ GRAKRFAKIA GEMVSLEMVE 
0631 QLALGVSPDK VHATAIKSDA SKGEALVLFT TDNELTRDKL QQYAREHGVP ELAVPRDIRY LKQMPLLGSG 
0701 KPDFVTLKSW VDEAEQHDE
Nucleotide
FASTA format

View sequence out neighbor 100bp 
-100                                             gcaggttttt tttcgcacct aatttactgt 
-070 cgctcgcgtt ctttatctcg tgtaatctcc ctccattcgc ttttactgaa tcagagcaaa gggagttgga 
0001 atgcttttta gcttttttcg aaatttgtgc cgtgttttgt atcgcgttcg cgttacgggt gacacccagg 
0071 cactgaaggg cgagcgcgtt ctaattacgc ctaatcacgt ctcttttatt gatggcattt tgcttggact 
0141 gtttttacct gtgcgtccag tgtttgccgt ttacacctca ataagccaac agtggtatat gcgttggctg 
0211 aaatcattta tcgactttgt tcctctcgac ccgacgcaac ctatggctat taaacatctg gtacgtctgg 
0281 tggaacaggg ccgaccagtg gtgattttcc ctgaaggacg catcaccacg acaggctcgc tgatgaaaat 
0351 ctacgatggc gcgggttttg tcgcggcgaa gtctggtgca acggttattc ctgtgcgtat tgaaggggcg 
0421 gaacttacgc acttcagccg cctgaaaggt ctggttaaac gtcgcttgtt cccgcaaatt actctgcata 
0491 ttttgccacc aacgcaggtg gcgatgccgg atgcgccgcg tgcccgtgac cgtcgcaaaa tcgctggcga 
0561 aatgctgcat caaataatga tggaagcgcg aatggcggtg cgcccgcgtg aaacgctgta cgaatcttta 
0631 ctgagtgcaa tgtaccgctt cggagccggg aagaaatgtg tcgaagacgt caactttacc ccagactcct 
0701 atcgcaaatt gcttacgaaa acgctgtttg ttggacgcat ccttgaaaaa tacagtgttg aaggcgaacg 
0771 catcggctta atgctgccca atgcaggcat cagtgcggca gtgatttttg gggccatcgc ccgtcgccgc 
0841 atgcccgcaa tgatgaacta cactgccggg gtaaaagggc tgaccagtgc tattacggcg gctgaaatca 
0911 aaaccatctt cacttcccgc cagtttctcg ataaaggcaa actctggcat ctgccggagc aacttactca 
0981 ggtgcgctgg gtctatctgg aagatttaaa agcagatgtc accactgccg acaaagtatg gatcttcgct 
1051 catttgctga tgccgcgtct ggcacaggtt aaacagcagc cggaagaaga ggcgctgatc ctttttacct 
1121 ccggttctga aggccatccg aaaggcgtcg tccatagcca taaaagcatt ctggcgaatg tcgagcagat 
1191 taaaacgatt gccgacttca ccaccaacga tcgctttatg tcggcgttac cgctgtttca ctcctttggg 
1261 ctgacggtag gcctgtttac gccactgctt acaggtgcag aagtgttcct ttatccaagc ccgctgcatt 
1331 accgcattgt gccggagttg gtgtatgacc gcagttgcac cgtgttgttc ggcacctcga ctttcctcgg 
1401 tcactacgcg cgtttcgcca acccgtatga cttctatcgt ctacgctatg tggtggcagg cgcagaaaaa 
1471 ttacaagaaa gtaccaaaca gctttggcag gataaatttg gcctgcgcat ccttgaaggc tacggcgtga 
1541 ccgaatgcgc gcctgtcgtt tctatcaacg taccgatggc ggcgaaaccc ggtacggtag ggcgtattct 
1611 accaggaatg gatgcgcgcc tgttgtcggt ccctggtatc gaagagggcg gacgcctgca actgaaaggg 
1681 ccgaacataa tgaacggcta tctgcgggtg gagaagccag gtgtactgga agtgcccacc gccgagaatg 
1751 ttcgcggcga aatggagcgc ggctggtatg acactggcga tattgtgcgt tttgacgagc agggctttgt 
1821 gcagattcag ggccgcgcaa aacgctttgc caaaattgca ggcgaaatgg tgtcgctgga aatggtggaa 
1891 caactggcac ttggtgtttc gccagataaa gtccatgcca ctgcgattaa gagcgatgcc agcaaaggcg 
1961 aggcactggt gcttttcacc acagataacg aactgacgcg cgataagttg caacagtatg cccgcgagca 
2031 cggcgtgccg gagcttgctg taccgcgcga tattcgctat ctgaaacaga tgccattact tggcagcggc 
2101 aaacctgact ttgtcacgtt gaaaagctgg gtagacgaag cggaacaaca cgatgagtga gtcagtgcac 
2171 actaacactt cgttgtggtc gaaggggatg aaagcggtta tcgtggcgca gtttctctct gcgtttggcg 
2241 ataatgccct actgtttgcc