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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
|
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
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|
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Deletion
|
LD3-18-1
(LD)
,
OCL45-4
(D)
|
|
Related gene (W3110 PEC)
|
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Gene Search
|
Search MG1655 PEC by gene name:
mazF
|
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Related strains
|
|
Strains Search
|
Search strains by gene name:
mazF
Search strains by all related name:
mazF b2782 chpA chpAK ECK2776 JW2753 mazF
|
General information (Go to Linear View: )
|
|
Gene Name
|
mazF
|
|
Alternative name
|
b2782,chpA,chpAK,ECK2776,JW2753,mazF
|
|
Location, Length
|
2,908,778 - 2,909,113
(
-
)
;
62.69
min
;
336
(bp) ,
111
(aa)
|
|
Product
|
mRNA interferase toxin, antitoxin is MazE
|
|
Operon Name
|
relA-chpRA-mazG
|
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Note
|
probable growth inhibitor, PemK-like, autoregulated
|
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Function
|
putative factor; Not classified
|
|
Gene Ontology
|
GO:0003677
;
DNA binding ( chpA )
GO:0005515
;
protein binding ( chpA )
|
|
PID
|
1789145
|
EC number
(KEGG Pathway)
|
|
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SWISS-PROT
(
Show details
)
|
Entry name(Acc.no)
|
CHPA_ECOLI
(
P33645
)
|
|
- Protein name
|
PemK-like protein 1
|
|
- Synonyms
|
MazF protein
|
|
- Gene name
|
OrderedLocusNames=b2782, z4097, ECs3642;
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Homology Analysis
|
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BLAST
|
|
Bacteria
|
|
GTOP
|
chpA
(
homologous genes of other bacterias
)
|
|
PDB
(database updated :
2007.02.20
)
|
|
PSI-BLAST
|
Chain A, Crystal Structure Of Mazef Complex
|
|
SWISS-PROT
(database updated :
2007.02.20
)
|
|
BLAST
|
PemK-like protein 1 (Protein mazF)
|
|
PSI-BLAST
|
PemK-like protein 1 (Protein mazF)
|
|
nr
(database updated :
2007.02.20
)
|
|
BLAST
|
probable growth inhibitor, PemK-like, autoregulated [Escherichia coli O157:H7 EDL933]
|
|
Pfam 28.0
(database updated :
2015-05
)
|
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Pfam
|
|
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PROSITE
|
|
PROSITE
|
ASN_GLYCOSYLATION
CAMP_PHOSPHO_SITE
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
MYRISTYL
|
|
MMBR References
|
J Bacteriol. 1993;175:6850-6856
chpA and chpB, Escherichia coli chromosomal homologs of the pem locus responsible for stable maintenance of plasmid R100.
Masuda, Y., K. Miyakawa, Y. Nishimura, and E. Ohtsubo.
|
Proc Natl Acad Sci U S A. 1996;93:6059-6063
An Escherichia coli chromosomal "addiction module" regulated by 3',5'-bispyrophosphate: a model for programmed bacterial cell death.
Aizenman, E., H. Engelberg-Kulka, and G. Glaser.
|
| Sequences |
Amino acid
FASTA format
|
0001 MVSRYVPDMG DLIWVDFDPT KGSEQAGHRP AVVLSPFMYN NKTGMCLCVP CTTQSKGYPF EVVLSGQERD
0071 GVALADQVKS IAWRARGATK KGTVAPEELQ LIKAKINVLI G
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 agcccgtatt tacgcttgct gaactggtca
-070 acgacatcac gccggaaaac ctccacgaga atatcgactg gggagagccg aaagataagg aagtctggta
0001 atggtaagcc gatacgtacc cgatatgggc gatctgattt gggttgattt tgacccgaca aaaggtagcg
0071 agcaagctgg acatcgtcca gctgttgtcc tgagtccttt catgtacaac aacaaaacag gtatgtgtct
0141 gtgtgttcct tgtacaacgc aatcaaaagg atatccgttc gaagttgttt tatccggtca ggaacgtgat
0211 ggcgtagcgt tagctgatca ggtaaaaagt atcgcctggc gggcaagagg agcaacgaag aaaggaacag
0281 ttgccccaga ggaattacaa ctcattaaag ccaaaattaa cgtactgatt gggtagtgtt actaactcac
0351 ttctattctg gtcacaggtt tccacctgac agacccgcaa ttttcaggac aattcaatga atcaaatcga
0421 ccgtttgctc actatt
|