MG1655
W3110
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Gene Report : srlR
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)  
     Deletion 21 (LD)  ,  OCL47,48-1 (LD 21_CRS) (D)  ,  OCL47,48-2 (LD 21_P/O) (D)  ,  OCL48 (D)  
Related gene (W3110 PEC)
     Gene Search Search MG1655 PEC by gene name:  srlR
Related strains
     Strains Search Search strains by gene name:  srlR   Search strains by all related name:  srlR b2707 ECK2702 gutR JW2676 slrR

General information  (Go to Linear View:)
 Gene Name srlR  
 Alternative name b2707,ECK2702,gutR,JW2676,slrR  
 Location, Length 2,827,069 - 2,827,842 (  +  ) ;   60.93 min ; 774 (bp) ,   257 (aa) Go to Linear View
 Product DNA-bindng transcriptional repressor  
 Operon Name srlAEBD-gutM-srlR-gutQ  
 Note regulator for gut (srl), glucitol operon; GO_component: GO:0005737 - cytoplasm; GO_process: GO:0016052 - carbohydrate catabolic process; GO_process: GO:0006350 - transcription; GO_process: GO:0006355 - regulation of transcription, DNA-dependent  
 Function regulator; Degradation of small molecules: Carbon compounds  
 Gene Ontology GO:0003677 ; DNA binding ( srlR )
GO:0003700 ; transcription factor activity ( srlR )
GO:0005622 ; intracellular ( srlR )
GO:0006350 ; transcription ( srlR )
GO:0006355 ; regulation of transcription, DNA-dependent ( srlR )
GO:0009401 ; phosphoenolpyruvate-dependent sugar phosphotransferase system ( srlR )
 PID 1789059  
 EC number
  (KEGG Pathway)
 
 
SWISS-PROT  ( Show details [ 2 more] )
  botton Entry name(Acc.no) SRLR_ECOLI ( P15082 ; P77030 )
    -  Protein name Glucitol operon repressor.  
    -  Synonyms  
    -  Gene name Name=srlR; Synonyms=gutR; OrderedLocusNames=b2707;  

 Linear View (Whole Mode)
View Location
   2815.0  –  2840.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP srlR (  homologous genes of other bacterias  )  
    PDB     (database updated : 2007.02.20 )
         PSI-BLAST Chain A, Crystal Structure Of The Thermotoga Maritima Iclr  
    SWISS-PROT     (database updated : 2007.02.20 )
         BLAST Glucitol operon repressor  
         PSI-BLAST Heat-inducible transcription repressor hrcA
    nr     (database updated : 2007.02.20 )
         BLAST DNA-bindng transcriptional repressor [Escherichia coli K12]  
Pfam 28.0   (database updated : 2015-05 )
    Pfam
PROSITE
    PROSITE ASN_GLYCOSYLATION    CAMP_PHOSPHO_SITE    PKC_PHOSPHO_SITE    CK2_PHOSPHO_SITE    MYRISTYL    AMIDATION    HTH_DEOR_FAMILY     

Other Cross-Reference
    COG COG1349KG 
    EcoCyc srlR 

MMBR References
Mol Gen Genet. 1981;183(3):497-504.
Physical mapping of the srl recA region of Escherichia coli: analysis of Tn10 generated insertions and deletions.
Willis DK, Uhlin BE, Amini KS, Clark AJ. ( 6278241 )

Sequences
Amino acid
FASTA format
0001 MKPRQRQAAI LEYLQKQGKC SVEELAQYFD TTGTTIRKDL VILEHAGTVI RTYGGVVLNK EESDPPIDHK 
0071 TLINTHKKEL IAEAAVSFIH DGDSIILDAG STVLQMVPLL SRFNNITVMT NSLHIVNALS ELDNEQTILM 
0141 PGGTFRKKSA SFHGQLAENA FEHFTFDKLF MGTDGIDLNA GVTTFNEVYT VSKAMCNAAR EVILMADSSK 
0211 FGRKSPNVVC SLESVDKLIT DAGIDPAFRQ ALEEKGIDVI ITGESNE

Nucleotide
FASTA format

View sequence out neighbor 100bp
-100                                             TCTATCATTG GCGCTTAAAC TGAAACGTGG 
-070 ATAATTTCGT TGTGAATGTT ACTTGCTTGC GAAGTTATCA TTTTGAAACC TAAATCAGGT AATCACGCCC 
0001 atgaaacctc gtcagcgtca ggccgccatt ctggagtatc tgcaaaagca gggtaaatgc tcggttgaag 
0071 aattggcgca atactttgac accacaggca caaccattcg caaagatctg gtcattctgg aacatgccgg 
0141 aaccgtcatt cgtacttatg gcggagtggt gttgaataaa gaggaatccg atccgcctat cgatcataaa 
0211 acactcatca acacccacaa gaaagagctg attgcagaag ctgccgttag ttttatccat gatggcgatt 
0281 cgatcattct tgatgctggc agtaccgttt tgcagatggt tcccctgctc tcgcgcttta ataacatcac 
0351 ggtgatgacc aacagcctgc atatcgtcaa tgcgctatcc gaactggata acgaacaaac tatcctgatg 
0421 ccaggcggaa cgtttcgcaa aaaatcggcc tcatttcacg ggcaactggc agagaatgcc ttcgagcatt 
0491 tcaccttcga taaattgttt atgggcaccg acggcatcga tctcaatgcg ggcgtaacca cctttaacga 
0561 ggtttatacc gtcagtaagg caatgtgcaa tgccgcgcgc gaagtgattt tgatggcgga ctcatcaaag 
0631 tttggccgta aaagccccaa cgtagtttgc agtcttgaaa gcgtcgataa gctgattacc gacgcaggta 
0701 tcgatccggc gtttcgtcag gcgctggaag agaaagggat cgatgtgatc ataaccggag agagcaatga 
0771 gtgaAGCACT ACTGAACGCG GGACGTCAGA CGTTAATGCT GGAGTTGCAG GAAGCAAGCC GTTTACCGGA 
0841 ACGTCTGGGC GATGATTTTG TTCGCGCCGC CAAT