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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
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Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
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Deletion
|
22
(LD)
,
OCL49,51-3 (LD 22B_CRS)
(D)
,
OCL49,51-4 (LD 22B_P/O)
(D)
,
OCL49-1
(D)
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Related gene (W3110 PEC)
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Gene Search
|
Search MG1655 PEC by gene name:
proW
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Related strains
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Strains Search
|
Search strains by gene name:
proW
Search strains by all related name:
proW b2678 ECK2672 JW2653 o354 osrA proU
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General information (Go to Linear View: )
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Gene Name
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proW
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Alternative name
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b2678,ECK2672,JW2653,o354,osrA,proU
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Location, Length
|
2,804,032 - 2,805,096
(
+
)
;
60.44
min
;
1065
(bp) ,
354
(aa)
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Product
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glycine betaine transporter subunit
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Operon Name
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proVWX
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Note
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high-affinity transport system for glycine betaine and proline; membrane component of ABC superfamily; GO_component: GO:0009274 - peptidoglycan-based cell wall; GO_component: GO:0019866 - organelle inner membrane;GO_function: GO:0015596 - glycine betaine/proline porter activity; GO_process: GO:0006561 - proline biosynthetic process
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Function
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transport; Transport of small molecules: Amino acids, amines
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Gene Ontology
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GO:0005215;
transporter activity ( proW )
GO:0005886;
plasma membrane ( proW )
GO:0006810;
transport ( proW )
GO:0006865;
amino acid transport ( proW )
GO:0016020;
membrane ( proW )
GO:0016021;
integral to membrane ( proW )
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PID
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1789033
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EC number
(KEGG Pathway)
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SWISS-PROT
(
Show details
[
2
more]
)
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Entry name(Acc.no)
|
PROW_ECOLI
(
P14176
)
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- Protein name
|
Glycine betaine/L-proline transport system permease protein proW.
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- Synonyms
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- Gene name
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Name=proW; OrderedLocusNames=b2678;
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MMBR References
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J Bacteriol. 1986;166(1):253-9.
Proline transport and osmotic stress response in Escherichia coli K-12.
Grothe S, Krogsrud RL, McClellan DJ, Milner JL, Wood JM.
(
3514577
)
|
J Bacteriol. 1996;178:5370-5381
Use of phoA and lacZ fusions to study the membrane topology of ProW, a component of the osmoregulated ProU transport system of Escherichia coli.
Haardt, M., and E. Bremer.
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Mol Microbiol. 1989;3(8):1025-38.
Molecular characterization of the proU loci of Salmonella typhimurium and Escherichia coli encoding osmoregulated glycine betaine transport systems.
Stirling DA, Hulton CS, Waddell L, Park SF, Stewart GS, Booth IR, Higgins CF.
(
2691838
)
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| Sequences |
Amino acid
FASTA format
|
0001 MADQNNPWDT TPAADSAAQS ADAWGTPTTA PTDGGGADWL TSTPAPNVEH FNILDPFHKT LIPLDSWVTE
0071 GIDWVVTHFR PVFQGVRVPV DYILNGFQQL LLGMPAPVAI IVFALIAWQI SGVGMGVATL VSLIAIGAIG
0141 AWSQAMVTLA LVLTALLFCI VIGLPLGIWL ARSPRAAKII RPLLDAMQTT PAFVYLVPIV MLFGIGNVPG
0211 VVVTIIFALP PIIRLTILGI NQVPADLIEA SRSFGASPRQ MLFKVQLPLA MPTIMAGVNQ TLMLALSMVV
0281 IASMIAVGGL GQMVLRGIGR LDMGLATVGG VGIVILAIIL DRLTQAVGRD SRSRGNRRWY TTGPVGLLTR
0351 PFIK
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Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 GCACCCTGTG CGGTGCCCGT GGTCGACGAG
-070 GACCAACAGT ATGTCGGCAT CATTTCGAAA GGAATGCTGC TGCGCGCTTT AGATCGTGAG GGGGTAAATA
0001 atggctgatc aaaataatcc gtgggatacc acgccagcgg cggacagtgc cgcgcaatcc gcagacgcct
0071 ggggtacacc gacgactgca ccgactgacg gcggtggtgc tgactggctg accagtacgc ctgcgccaaa
0141 cgtcgagcat tttaatattc tcgatccgtt ccataaaacg ctgatcccgc tcgacagttg ggtcactgaa
0211 gggatcgact gggtcgttac ccatttccgt cccgtcttcc agggcgtgcg cgttccggtt gattatatcc
0281 tcaacggttt ccagcaattg ctgctgggta tgcccgcacc ggtggcgatt atcgttttcg ctctcatcgc
0351 ctggcagatt tccggggtcg gaatgggtgt ggcgacgctg gtttcgctga ttgccatcgg cgcaatcggt
0421 gcctggtcgc aggcaatggt gactctggcg ctggtgttaa ccgccctgct gttctgtatc gtcatcggtt
0491 tgccgttggg gatatggctg gcgagaagtc cgcgagcggc gaaaattatt cgtccactgc ttgatgccat
0561 gcagaccacg ccagcgtttg tttatctggt gccaatcgtc atgctatttg gtatcggtaa cgtgccgggc
0631 gtggtggtga cgatcatctt tgctctgccg ccgattatcc gtctgaccat tctggggatt aaccaggttc
0701 cggcggatct gattgaagcc tcgcgctcat tcggtgccag cccgcgccag atgctgttca aagttcagtt
0771 accgctggcg atgccgacca ttatggcggg cgttaaccag acgctgatgc tggccctttc tatggtggtc
0841 atcgcctcga tgattgccgt cggcgggttg ggtcagatgg tacttcgcgg tatcggtcgt ctggatatgg
0911 ggcttgccac cgttggcggc gtcgggattg tgatcctcgc cattatcctc gatcgtctga cgcaggccgt
0981 tgggcgcgac tcacgcagtc gcggcaaccg tcgctggtac accactggcc ctgttggtct gctgacccgc
1051 ccattcatta agtaaCTCTG CACTTGCCCG GTGACGCCGG GCATTATCAC CCTGCCAAAA AAAGGAATAA
1121 CAATGCGACA TAGCGTACTT TTTGCGACAG CGTTTGCCAC GCTTA
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