|
PEC Original Annotations
|
|
Essentiality
|
|
Class
|
non-essential
|
|
References (PMID)
|
J Bacteriol. 1993;175(1):229-39.
Analysis of mRNA decay and rRNA processing in Escherichia coli multiple mutants carrying a deletion in RNase III.
Babitzke P, Granger L, Olszewski J, Kushner SR.
(
8416898
)
|
|
|
Deletion
|
OCL53,54-1
(D)
|
|
Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
rnc
|
|
Related strains
|
|
Strains Search
|
Search strains by gene name:
rnc
Search strains by all related name:
rnc b2567 ECK2565 JW2551 ranA
|
General information (Go to Linear View: )
|
|
Gene Name
|
rnc
|
|
Alternative name
|
b2567,ECK2565,JW2551,ranA
|
|
Location, Length
|
2,701,405 - 2,702,085
(
-
)
;
58.22
min
;
681
(bp) ,
226
(aa)
|
|
Product
|
RNase III
|
|
Operon Name
|
rnc-era-recO-pdxJ-acpS
|
|
Note
|
RNase III, ds RNA; GO_process: GO:0006401 - RNA catabolic process
|
|
Function
|
enzyme; Degradation of RNA
|
|
Gene Ontology
|
GO:0003723
;
RNA binding ( rnc )
GO:0003725
;
double-stranded RNA binding ( rnc )
GO:0004518
;
nuclease activity ( rnc )
GO:0004519
;
endonuclease activity ( rnc )
GO:0004525
;
ribonuclease III activity ( rnc )
GO:0005515
;
protein binding ( rnc )
GO:0005622
;
intracellular ( rnc )
GO:0005737
;
cytoplasm ( rnc )
GO:0006364
;
rRNA processing ( rnc )
GO:0006396
;
RNA processing ( rnc )
GO:0006397
;
mRNA processing ( rnc )
GO:0016075
;
rRNA catabolic process ( rnc )
GO:0016787
;
hydrolase activity ( rnc )
|
|
PID
|
1788920
|
EC number
(KEGG Pathway)
|
3.1.26.3
|
|
SWISS-PROT
(
Show details
)
|
Entry name(Acc.no)
|
RNC_ECOLI
(
P05797
;
P06141
)
|
|
- Protein name
|
Ribonuclease III
|
|
- Synonyms
|
EC 3.1.26.3, RNase III
|
|
- Gene name
|
OrderedLocusNames=b2567, c3091, z3848, ECs3433, SF2629, S2802;
|
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Homology Analysis
|
|
BLAST
|
|
Bacteria
|
|
GTOP
|
rnc
(
homologous genes of other bacterias
)
|
|
PDB
(database updated :
2007.02.20
)
|
|
PSI-BLAST
|
Chain A, Crystal Structure Of Ribonuclease Iii (Tm1102) From Thermotoga Maritima At 2.0 A Resolution
|
|
SWISS-PROT
(database updated :
2007.02.20
)
|
|
BLAST
|
Ribonuclease III (RNase III)
|
|
PSI-BLAST
|
Ribonuclease III
|
|
nr
(database updated :
2007.02.20
)
|
|
BLAST
|
ribonuclease III [Escherichia coli O157:H7 EDL933]
|
|
Pfam 28.0
(database updated :
2015-05
)
|
|
Pfam
|
|
|
PROSITE
|
|
PROSITE
|
CAMP_PHOSPHO_SITE
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
MYRISTYL
RIBONUCLEASE_III
|
|
MMBR References
|
Biochimie. 1995;77(4):294-302.
Lethal double-stranded RNA processing activity of ribonuclease III in the absence of suhB protein of Escherichia coli.
Inada T, Nakamura Y.
(
8589060
)
|
Nucleic Acids Res. 1985;13:4677-4685
The DNA sequence of the gene (rnc) encoding ribonuclease III of Escherichia coli.
March, P. E., J. Ahnn, and M. Inouye.
|
RNA 1996;2:1228-1240
RNase III autoregulation: structure and function of rncO, the posttranscriptional "operator".
Matsunaga, J., E. L. Simons, and R. W. Simons.
|
Mol Gen Genet. 1985;201(1):25-9.
DNA sequencing of the Escherichia coli ribonuclease III gene and its mutations.
Nashimoto H, Uchida H.
(
3903434
)
|
J Bacteriol. 1989;171(5):2581-90.
Genetic analysis of the rnc operon of Escherichia coli.
Takiff HE, Chen SM, Court DL.
(
2540151
)
|
Proc Natl Acad Sci U S A. 1985;82:849-853
Molecular cloning of the gene for the RNA-processing enzyme RNase III of Escherichia coli.
Watson, N., and D. Apirion.
|
J Biol Chem. 1990;265:2888-2895
Expression and characterization of RNase III and Era proteins. Products of the rnc operon of Escherichia coli.
Chen, S. M., H. E. Takiff, A. M. Barber, G. C. Dubois, J. C. Bardwell, and D. L. Court.
|
| Sequences |
Amino acid
FASTA format
|
0001 MNPIVINRLQ RKLGYTFNHQ ELLQQALTHR SASSKHNERL EFLGDSILSY VIANALYHRF PRVDEGDMSR
0071 MRATLVRGNT LAELAREFEL GECLRLGPGE LKSGGFRRES ILADTVEALI GGVFLDSDIQ TVEKLILNWY
0141 QTRLDEISPG DKQKDPKTRL QEYLQGRHLP LPTYLVVQVR GEAHDQEFTI HCQVSGLSEP VVGTGSSRRK
0211 AEQAAAEQAL KKLELE
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 taccggtaaa ctgaaactgc agcgaagcag
-070 ttagcagaac catgtatatc aggtctgttt cgtgtgctga attgttgacg catttattta ttggtatcgc
0001 atgaacccca tcgtaattaa tcggcttcaa cggaagctgg gctacacttt taatcatcag gaactgttgc
0071 agcaggcatt aactcatcgt agtgccagca gtaaacataa cgagcgttta gaatttttag gcgactctat
0141 tctgagctac gttatcgcca atgcgcttta tcaccgtttc cctcgtgtgg atgaaggcga tatgagccgg
0211 atgcgcgcca cgctggtccg tggcaatacg ctggcggaac tggcgcgcga atttgagtta ggcgagtgct
0281 tacgtttagg gccaggtgaa cttaaaagcg gtggatttcg tcgtgagtca attctcgccg acaccgtcga
0351 agcattaatt ggtggcgtat tcctcgacag tgatattcaa accgtcgaga aattaatcct caactggtat
0421 caaactcgtt tggacgaaat tagcccaggc gataaacaaa aagatccgaa aacgcgcttg caagaatatt
0491 tgcagggtcg ccatctgccg ctgccgactt atctggtagt ccaggtacgt ggcgaagcgc acgatcagga
0561 atttactatc cactgccagg tcagcggcct gagtgaaccg gtggttggca caggttcaag ccgtcgtaag
0631 gctgagcagg ctgccgccga acaggcgttg aaaaaactgg agctggaatg agcatcgata aaagttactg
0701 cggatttatt gccatcgtcg gacgtccgaa cgttggcaaa tccacattgt tgaacaaact gctggggcag
0771 aaaatctcca t
|
