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PEC Original Annotations
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Essentiality
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Class
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essential
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References (PMID)
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FEMS Microbiol Lett. 1996;143(1):47-55.
Deletion of the putative effector region of Era, an essential GTP-binding protein in Escherichia coli, causes a dominant-negative phenotype.
Pillutla RC, Ahnn J, Inouye M.
(
8807801
)
|
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Deletion
|
OCL53,54-1
(D)
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Related gene (W3110 PEC)
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Gene Search
|
Search MG1655 PEC by gene name:
era
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Related strains
|
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Strains Search
|
Search strains by gene name:
era
Search strains by all related name:
era b2566 ECK2564 JW2550 sdgE
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General information (Go to Linear View: )
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Gene Name
|
era
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Alternative name
|
b2566,ECK2564,JW2550,sdgE
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Location, Length
|
2,700,503 - 2,701,408
(
-
)
;
58.20
min
;
906
(bp) ,
301
(aa)
|
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Product
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membrane-associated, 16S rRNA-binding GTPase
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Operon Name
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rnc-era-recO-pdxJ-acpS
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Note
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GTP-binding protein; GO_process: GO:0007049 - cell cycle
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Function
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factor; Global regulatory functions
|
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Gene Ontology
|
GO:0000166
;
nucleotide binding ( era )
GO:0003723
;
RNA binding ( era )
GO:0005525
;
GTP binding ( era )
GO:0005622
;
intracellular ( era )
GO:0005886
;
plasma membrane ( era )
GO:0009987
;
cellular process ( era )
GO:0016020
;
membrane ( era )
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PID
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1788919
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EC number
(KEGG Pathway)
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SWISS-PROT
(
Show details
[
2
more]
)
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Entry name(Acc.no)
|
ERA_ECOLI
(
P06616
)
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- Protein name
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GTP-binding protein era.
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- Synonyms
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- Gene name
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Name=era; Synonyms=rbaA; OrderedLocusNames=b2566;
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Homology Analysis
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BLAST
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Bacteria
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GTOP
|
era
(
homologous genes of other bacterias
)
|
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PDB
(database updated :
2007.02.20
)
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PSI-BLAST
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Chain A, Crystal Structure Of A Widely Conserved Gtpase Era
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SWISS-PROT
(database updated :
2007.02.20
)
|
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BLAST
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GTP-binding protein era
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PSI-BLAST
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GTP-binding protein era homolog
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nr
(database updated :
2007.02.20
)
|
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BLAST
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GTP-binding protein Era [Escherichia coli K12]
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Pfam 28.0
(database updated :
2015-05
)
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Pfam
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PROSITE
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PROSITE
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PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
MYRISTYL
ATP_GTP_A
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MMBR References
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Mol Microbiol. 1991;5(4):951-7.
Pleiotropic changes resulting from depletion of Era, an essential GTP-binding protein in Escherichia coli.
Lerner CG, Inouye M.
(
1906969
)
|
Proc Natl Acad Sci U S A. 1986;83:8849-8853
A GTP-binding protein of Escherichia coli has homology to yeast RAS proteins.
Ahnn, J., P. E. March, H. E. Takiff, and M. Inouye.
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Mol Microbiol. 1994;12(2):201-8.
Characterization of the autophosphorylation of Era, an essential Escherichia coli GTPase.
Sood P, Lerner CG, Shimamoto T, Lu Q, Inouye M.
(
8057845
)
|
J Biol Chem. 1990;265:2888-2895
Expression and characterization of RNase III and Era proteins. Products of the rnc operon of Escherichia coli.
Chen, S. M., H. E. Takiff, A. M. Barber, G. C. Dubois, J. C. Bardwell, and D. L. Court.
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| Sequences |
Amino acid
FASTA format
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0001 MSIDKSYCGF IAIVGRPNVG KSTLLNKLLG QKISITSRKA QTTRHRIVGI HTEGAYQAIY VDTPGLHMEE
0071 KRAINRLMNK AASSSIGDVE LVIFVVEGTR WTPDDEMVLN KLREGKAPVI LAVNKVDNVQ EKADLLPHLQ
0141 FLASQMNFLD IVPISAETGL NVDTIAAIVR KHLPEATHHF PEDYITDRSQ RFMASEIIRE KLMRFLGAEL
0211 PYSVTVEIER FVSNERGGYD INGLILVERE GQKKMVIGNK GAKIKTIGIE ARKDMQEMFE APVHLELWVK
0281 VKSGWADDER ALRSLGYVDD L
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Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 aggtcagcgg cctgagtgaa ccggtggttg
-070 gcacaggttc aagccgtcgt aaggctgagc aggctgccgc cgaacaggcg ttgaaaaaac tggagctgga
0001 atgagcatcg ataaaagtta ctgcggattt attgccatcg tcggacgtcc gaacgttggc aaatccacat
0071 tgttgaacaa actgctgggg cagaaaatct ccatcacttc ccgcaaggcg cagacaactc gtcaccgcat
0141 tgtggggatc catactgaag gcgcgtatca ggcgatctac gtcgatacac cgggcctgca tatggaagaa
0211 aaacgcgcca ttaaccgcct gatgaacaaa gcggcgagca gctctattgg cgatgttgag ctggtgattt
0281 ttgtcgttga aggcacccgc tggacgccgg acgacgaaat ggtgctcaac aaactgcgcg aaggcaaagc
0351 gccggtaatc ctcgcggtga acaaagtgga caacgtgcag gagaaagccg atctgctgcc gcacctgcag
0421 ttcctggcaa gccagatgaa cttcctcgat atcgtgccaa tctctgccga aaccgggctg aatgttgaca
0491 ctattgcggc aatcgtgcgt aagcatctac ctgaagcgac tcatcacttc ccggaagatt acatcaccga
0561 tcgctcacag cgttttatgg cgtctgaaat catccgcgaa aaactgatgc gtttcctcgg cgctgaactg
0631 ccgtactccg tgaccgtgga gatcgaacgt ttcgtctcta acgaacgcgg tggttatgac atcaacggtt
0701 tgattctcgt tgagcgtgaa gggcagaaga agatggtcat tggcaacaaa ggggccaaga tcaaaaccat
0771 cgggattgaa gcgcgtaaag acatgcagga aatgttcgaa gcgcctgttc accttgaact gtgggtaaaa
0841 gtgaaatccg gttgggccga cgacgaacgc gcactgcgca gtctcggtta cgttgacgat ctttaagagt
0911 aactccgatg gaaggctggc agcgcgcatt tgtcctgcat agtcgcccgt ggagcgaaac cagcctgatg
0981 ctggacgtct tcacggagga atcggg
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