MG1655
W3110
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Gene Report : cysZ
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
     Deletion OCL60,61-1 (D)  
Related gene (W3110 PEC)
     Gene Search Search MG1655 PEC by gene name:  cysZ
Related strains
     Strains Search Search strains by gene name:  cysZ   Search strains by all related name:  cysZ b2413 ECK2408 JW2406 o253

General information  (Go to Linear View:)
 Gene Name cysZ  
 Alternative name b2413,ECK2408,JW2406,o253  
 Location, Length 2,529,485 - 2,530,246 (  +  ) ;   54.52 min ; 762 (bp) ,   253 (aa) Go to Linear View
 Product putative inner membrane protein  
 Operon Name cysZ  
 Note required for sulfate transport; GO_component: GO:0009274 - peptidoglycan-based cell wall; GO_component: GO:0019866 - organelle inner membrane; GO_process: GO:0006790 - sulfur metabolic process  
 Function transport; Transport of small molecules: Anions  
 Gene Ontology GO:0005886 ; plasma membrane ( cysZ )
GO:0006810 ; transport ( cysZ )
GO:0008272 ; sulfate transport ( cysZ )
GO:0008652 ; amino acid biosynthetic process ( cysZ )
GO:0009276 ; 1-2nm peptidoglycan-based cell wall ( cysZ )
GO:0016020 ; membrane ( cysZ )
GO:0016021 ; integral to membrane ( cysZ )
GO:0019344 ; cysteine biosynthetic process ( cysZ )
 PID 1788753  
 EC number
  (KEGG Pathway)
 
 
SWISS-PROT  ( Show details [ 2 more] )
  botton Entry name(Acc.no) CYSK_ECOLI ( P11096 ; P21546 )
    -  Protein name Cysteine synthase A  
    -  Synonyms EC 2.5.1.47, O-acetylserine sulfhydrylase A, O- acetylserine (Thiol)-lyase A, CSase A, Sulfate starvation-induced protein 5, SSI5  
    -  Gene name Name=cysK; Synonyms=cysZ; OrderedLocusNames=b2414, z3680, ECs3286;  

 Linear View (Whole Mode)
View Location
   2520.0  –  2545.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP cysZ (  homologous genes of other bacterias  )  
    PDB     (database updated : 2007.02.20 )
        PSI-BLAST  
    SWISS-PROT     (database updated : 2007.02.20 )
         BLAST Protein cysZ  
         PSI-BLAST Protein cysZ
    nr     (database updated : 2007.02.20 )
         BLAST putative sulfate transport protein CysZ [Escherichia coli O157:H7 EDL933]  
Pfam 28.0   (database updated : 2015-05 )
    Pfam
PROSITE
    PROSITE CAMP_PHOSPHO_SITE    PKC_PHOSPHO_SITE    CK2_PHOSPHO_SITE    MYRISTYL     

Other Cross-Reference
    COG COG2981E 
    EcoCyc cysZ 

MMBR References
J Bacteriol. 1988;170(7):3150-7.
DNA sequences of the cysK regions of Salmonella typhimurium and Escherichia coli and linkage of the cysK regions to ptsH.
Byrne CR, Monroe RS, Ward KA, Kredich NM. ( 3290198 )

Sequences
Amino acid
FASTA format
0001 MVSSFTSAPR SGFYYFAQGW KLVSQPGIRR FVILPLLVNI LLMGGAFWWL FTQLDVWIPT LMSYVPDWLQ 
0071 WLSYLLWPLA VISVLLVFGY FFSTIANWIA APFNGLLAEQ LEARLTGATP PDTGIFGIMK DVPRIMKREW 
0141 QKFAWYLPRA IVLLILYFIP GIGQTVAPVL WFLFSAWMLA IQYCDYPFDN HKVPFKEMRT ALRTRKITNM 
0211 QFGALTSLFT MIPLLNLFIM PVAVCGATAM WVDCYRDKHA MWR

Nucleotide
FASTA format

View sequence out neighbor 100bp
-100                                             TTGCTGTTTT TTCGAACATA TCCTAACTGT 
-070 CCATTGCGCA ATTACCCGGT AAAATACGCA GAATTTTCCT GGGATTGGTC AAAAGGAGCT CATCCTGATT 
0001 atggtttcat cattcacatc tgccccacgc agcggttttt actattttgc gcaaggctgg aagctcgtct 
0071 cgcaacctgg gattcggcgt ttcgttattt taccgctgct ggtcaatatt ttgttgatgg ggggcgcatt 
0141 ctggtggctc tttacacagc tcgatgtctg gatcccgact ctcatgagtt acgttccgga ctggctacaa 
0211 tggctgagtt atctgttgtg gcctctggct gtcatctctg tgctgttagt gtttggctat ttcttctcca 
0281 cgattgctaa ctggattgcc gctccgttta acggtttatt ggctgaacaa ctggaagcac gattgactgg 
0351 cgctacaccg ccagataccg ggattttcgg tatcatgaaa gatgtgccgc gaatcatgaa acgcgaatgg 
0421 caaaaatttg cctggtatct gccgcgcgca attgtattac taattcttta cttcatccct ggtattgggc 
0491 aaaccgtcgc gccggtactg tggttcctgt ttagcgcctg gatgttagcc atccagtatt gcgattaccc 
0561 cttcgataac cacaaagtgc cgtttaaaga gatgcgcacc gccctgcgca cacgcaaaat caccaatatg 
0631 cagtttggtg ctttaaccag cctgtttacg atgatcccgc tgcttaatct gttcatcatg cccgttgccg 
0701 tttgtggcgc gacggcgatg tgggtcgatt gctatcgcga taaacacgcg atgtggcggt aaCAATCTAC 
0771 CGGTTATTTT GTAAACCGTT TGTGTGAAAC AGGGGTGGCT TATGCCGCCC CTTATTCCAT CTTGCATGTC 
0841 ATTATTTCCC TTCTGTATAT AG