MG1655
W3110
Search for
Japanese | English
Gene Report : hisQ
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
     Deletion OCL64 (D)  ,  OCL64-3 (D)  
Related gene (W3110 PEC)
     Gene Search Search MG1655 PEC by gene name:  hisQ
Related strains
     Strains Search Search strains by gene name:  hisQ   Search strains by all related name:  hisQ b2308 ECK2302 JW2305

General information  (Go to Linear View:)
 Gene Name hisQ  
 Alternative name b2308,ECK2302,JW2305  
 Location, Length 2,423,252 - 2,423,938 (  -  ) ;   52.23 min ; 687 (bp) ,   228 (aa) Go to Linear View
 Product histidine/lysine/arginine/ornithine transporter permease subunit  
 Operon Name argT-hisJQMP  
 Note histidine transport system permease protein; membrane component of ABC superfamily; GO_component: GO:0009274 - peptidoglycan-based cell wall; GO_component: GO:0019866 - organelle inner membrane; GO_process: GO:0009089 - lysine biosynthetic process via diaminopimelate; GO_process: GO:0006526 - arginine biosynthetic process  
 Function transport; Transport of small molecules: Amino acids, amines  
 Gene Ontology GO:0005215; transporter activity ( hisQ )
GO:0005886; plasma membrane ( hisQ )
GO:0006810; transport ( hisQ )
GO:0006865; amino acid transport ( hisQ )
GO:0009276; 1-2nm peptidoglycan-based cell wall ( hisQ )
GO:0016020; membrane ( hisQ )
GO:0016021; integral to membrane ( hisQ )
 PID 1788646  
 EC number
  (KEGG Pathway)
 
 
SWISS-PROT  ( Show details [ 2 more] )
  botton Entry name(Acc.no) HISQ_ECOLI ( P52094 ; P77635 )
    -  Protein name Histidine transport system permease protein hisQ.  
    -  Synonyms  
    -  Gene name Name=hisQ; OrderedLocusNames=b2308;  

 Linear View (Whole Mode)
View Location
   2410.0  –  2435.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP hisQ (  homologous genes of other bacterias  )  
    PDB     (database updated : 2007.02.20 )
        PSI-BLAST  
    SWISS-PROT     (database updated : 2007.02.20 )
         BLAST Histidine transport system permease protein hisQ  
         PSI-BLAST Glutamate transport system permease protein gluD
    nr     (database updated : 2007.02.20 )
         BLAST histidine/lysine/arginine/ornithine transporter subunit [Escherichia coli K12]  
Pfam 28.0   (database updated : 2015-05 )
    Pfam
PROSITE
    PROSITE CAMP_PHOSPHO_SITE    PKC_PHOSPHO_SITE    CK2_PHOSPHO_SITE    TYR_PHOSPHO_SITE    MYRISTYL    ATP_GTP_A    BPD_TRANSP_INN_MEMBR     

Other Cross-Reference
    COG COG4215E 
    EcoCyc hisQ 

MMBR References
J. Supramol. Struct. (Suppl.) 1980;13:117-130.
Cloning of the histidine transport genes from Salmonella typhimurium and characterization of an analogous transport system in Escherichia coli.
Ardeshir, F., and G. F.-L. Ames.

Sequences
Amino acid
FASTA format
0001 MLYGFSGVIL QGALVTLELA ISSVVLAVII GLIGAGGKLS QNRLSGLIFE GYTTLIRGVP DLVLMLLIFY 
0071 GLQIALNTVT EAMGVGQIDI DPMVAGIITL GFIYGAYFTE TFRGAFMAVP KGHIEAATAF GFTRGQVFRR 
0141 IMFPSMMRYA LPGIGNNWQV ILKSTALVSL LGLEDVVKAT QLAGKSTWEP FYFAIVCGVI YLVFTTVSNG 
0211 VLLFLERRYS VGVKRADL

Nucleotide
FASTA format

View sequence out neighbor 100bp
-100                                             atggtggcta atcgccatcg gtgaaagaaa 
-070 gcccgctccc ttcgggtaac cggagggaga caagaggcgg taattcacca cacacgacag gacaggcagc 
0001 atgttgtatg ggttttcagg tgttatttta cagggtgcgc tcgtcacgct ggagctggct atcagctctg 
0071 tagtgctcgc tgtaatcatc ggtttaattg gcgctggcgg taagctctcg caaaatcggc tttcggggct 
0141 gattttcgaa gggtacacca cgctgattcg tggcgtgccg gacttagtgt tgatgctgct gattttctac 
0211 ggtttgcaga ttgcgctaaa cacggtgacg gaggcgatgg gcgtcgggca gattgatatc gatccgatgg 
0281 tcgctggtat tatcactctc ggttttatct acggtgctta ttttaccgaa acgttccgtg gtgcttttat 
0351 ggcagtgccg aaaggacata tagaggcggc gacggcgttc ggttttactc gtgggcaagt gtttcggcgg 
0421 atcatgtttc cgtcgatgat gcgttacgcc ctgccaggca ttggcaacaa ctggcaggtg atcctcaaat 
0491 ctaccgcact ggtttcgtta ctcggcctgg aagatgtggt caaagccacc caactggcag gcaaaagtac 
0561 ctgggaaccg ttctatttcg ccatcgtctg tggcgtgatt tacctggttt tcaccactgt ttccaatggt 
0631 gtgctgctgt tccttgagcg ccgctactcc gtgggtgtga agagggctga cctgtgatcg aaatcttaca 
0701 tgaatactgg aaaccgctgc tgtggaccga cggttatcgc tttactggtg tggcgatcac tctgtggctg 
0771 cttattttgt cggtagt