|
PEC Original Annotations
|
|
Essentiality
|
|
Class
|
non-essential
|
|
References (PMID)
|
Biochem J. 1998;334 (Pt 2):355-65.
Transcriptional control and essential roles of the Escherichia coli ccm gene products in formate-dependent nitrite reduction and cytochrome c synthesis.
Tanapongpipat S, Reid E, Cole JA, Crooke H.
(
9716493
)
|
|
|
Deletion
|
14
(LD)
,
OCL70,72-3 (LD 14B_CRS)
(D)
,
OCL70,72-4 (LD 14C_P/O)
(D)
,
OCL72
(D)
|
|
Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
ccmD
|
|
Related strains
|
|
Strains Search
|
Search strains by gene name:
ccmD
Search strains by all related name:
ccmD b2198 ECK2190 JW2186 yojM
|
General information (Go to Linear View: )
|
|
Gene Name
|
ccmD
|
|
Alternative name
|
b2198,ECK2190,JW2186,yojM
|
|
Location, Length
|
2,293,399 - 2,293,608
(
-
)
;
49.43
min
;
210
(bp) ,
69
(aa)
|
|
Product
|
cytochrome c biogenesis protein
|
|
Operon Name
|
napFDAGHBC-ccmABCDEFGH
|
|
Note
|
heme exporter protein C; GO_component: GO:0009274 - peptidoglycan-based cell wall; GO_component: GO:0019866 - organelle inner membrane; GO_process: GO:0017004 - cytochrome complex assembly; GO_process: GO:0006457 - protein folding
|
|
Function
|
transport; Protein, peptide secretion
|
|
Gene Ontology
|
GO:0005886
;
plasma membrane ( ccmD )
GO:0006810
;
transport ( ccmD )
GO:0016020
;
membrane ( ccmD )
GO:0016021
;
integral to membrane ( ccmD )
GO:0017004
;
cytochrome complex assembly ( ccmD )
|
|
PID
|
1788526
|
EC number
(KEGG Pathway)
|
|
|
SWISS-PROT
(
Show details
)
|
Entry name(Acc.no)
|
CCMD_ECOLI
(
P36770
)
|
|
- Protein name
|
Heme exporter protein D
|
|
- Synonyms
|
Cytochrome c-type biogenesis protein ccmD
|
|
- Gene name
|
OrderedLocusNames=b2198, c2735, z3455, ECs3087, SF2282, S2412;
|
|
Homology Analysis
|
|
BLAST
|
|
Bacteria
|
|
GTOP
|
ccmD
(
homologous genes of other bacterias
)
|
|
PDB
(database updated :
2007.02.20
)
|
|
PSI-BLAST
|
|
|
SWISS-PROT
(database updated :
2007.02.20
)
|
|
BLAST
|
Heme exporter protein D (Cytochrome c-type biogenesis protein ccmD)
|
|
PSI-BLAST
|
Heme exporter protein D
|
|
nr
(database updated :
2007.02.20
)
|
|
BLAST
|
heme exporter protein C [Escherichia coli O157:H7 EDL933]
|
|
Pfam 28.0
(database updated :
2015-05
)
|
|
Pfam
|
|
|
PROSITE
|
|
PROSITE
|
CK2_PHOSPHO_SITE
|
|
MMBR References
|
Mol Microbiol. 1996;19(3):467-81.
Escherichia coli K-12 genes essential for the synthesis of c-type cytochromes and a third nitrate reductase located in the periplasm.
Grove J, Tanapongpipat S, Thomas G, Griffiths L, Crooke H, Cole J.
(
8830238
)
|
J Bacteriol. 1995;177:4321-4326
Escherichia coli genes required for cytochrome c maturation.
Thony-Meyer, L., F. Fischer, P. Kunzler, D. Ritz, and H. Hennecke.
|
J Bacteriol. 1991;173(19):6139-46.
Anaerobically expressed Escherichia coli genes identified by operon fusion techniques.
Choe M, Reznikoff WS.
(
1917846
)
|
J Bacteriol. 1993;175:1165-1172
Identification of the regulatory sequence of anaerobically expressed locus aeg-46.5.
Choe, M., and W. S. Reznikoff.
|
| Sequences |
Amino acid
FASTA format
|
0001 MTPAFASWNE FFAMGGYAFF VWLAVVMTVI PLVVLVVHSV MQHRAILRGV AQQRAREARL RAAQQQEAA
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 tgtctgccac gctgacgctg atgcggatgc
-070 gtaatttgat tttgctgatg gaaaaacgcc gtccgtgggt gagtgaactg atactgaaaa gaggccgtaa
0001 atgacccctg catttgcttc ctggaatgaa tttttcgcaa tgggcggtta cgcctttttt gtctggctgg
0071 cggtggtgat gaccgttatt ccgctggtgg ttttggtcgt gcactcggtg atgcaacatc gcgcaattct
0141 gcgtggcgtg gcgcaacagc gggcgcgtga ggcgcgttta cgtgctgcgc aacagcagga ggctgcatga
0211 atattcgccg taaaaaccgc ttgtggattg cctgtgccgt gttggcaggg ctggcgctga ctatcggtct
0281 ggtgctatat gcgctgcgct cgaatatcga
|
