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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
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Deletion
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OCR36
(D)
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|
Related gene (W3110 PEC)
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Gene Search
|
Search MG1655 PEC by gene name:
gmhA
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Related strains
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Strains Search
|
Search strains by gene name:
gmhA
Search strains by all related name:
gmhA b0222 ECK0223 gmhA isn JW0212 lpcA tfrA yafI
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General information (Go to Linear View: )
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Gene Name
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gmhA
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Alternative name
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b0222,ECK0223,gmhA,isn,JW0212,lpcA,tfrA,yafI
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Location, Length
|
243,543 - 244,121
(
+
)
;
5.25
min
;
579
(bp) ,
192
(aa)
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Product
|
D-sedoheptulose 7-phosphate isomerase
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Operon Name
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lpcA
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Note
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phosphoheptose isomerase; GO_component: GO:0005737 - cytoplasm; GO_function: GO:0042280 - cell surface antigen activity, host-interacting; GO_process: GO:0009244 - lipopolysaccharide core region biosynthetic process
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Function
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enzyme; Surface polysaccharides & antigens
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Gene Ontology
|
GO:0005529
;
sugar binding ( gmhA )
GO:0005737
;
cytoplasm ( gmhA )
GO:0005975
;
carbohydrate metabolic process ( gmhA )
GO:0008968
;
D-sedoheptulose 7-phosphate isomerase activity ( gmhA )
GO:0009103
;
lipopolysaccharide biosynthetic process ( gmhA )
GO:0009244
;
lipopolysaccharide core region biosynthetic process ( gmhA )
GO:0016853
;
isomerase activity ( gmhA )
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PID
|
1786416
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EC number
(KEGG Pathway)
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5.-.-.-
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SWISS-PROT
(
Show details
)
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Entry name(Acc.no)
|
LPCA_ECOLI
(
P51001
)
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- Protein name
|
Phosphoheptose isomerase
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- Synonyms
|
EC 5.-.-.-
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- Gene name
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OrderedLocusNames=b0222, c0372, z0280, ECs0249, SF0272, S0293;
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Homology Analysis
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BLAST
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Bacteria
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GTOP
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lpcA
(
homologous genes of other bacterias
)
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PDB
(database updated :
2007.02.20
)
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PSI-BLAST
|
Chain A, Crystal Structure Of A Hypothetical Protein
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SWISS-PROT
(database updated :
2007.02.20
)
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BLAST
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Phosphoheptose isomerase (Sedoheptulose 7-phosphate isomerase)
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PSI-BLAST
|
Phosphoheptose isomerase
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|
nr
(database updated :
2007.02.20
)
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BLAST
|
phosphoheptose isomerase [Escherichia coli UTI89]
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Pfam 28.0
(database updated :
2015-05
)
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Pfam
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PROSITE
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PROSITE
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PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
MYRISTYL
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MMBR References
|
Mol Gen Genet. 1989;215(3):369-73.
Accurate mapping of the Escherichia coli pepD gene by sequence analysis of its 5' flanking region.
Henrich B, Schroeder U, Frank RW, Plapp R.
(
2651887
)
|
Mol Gen Genet. 1976;147(3):263-9.
Heptose-deficient mutants of Escherichia coli K12 deficient in up to three major outer membrane proteins.
van Alphen W, Lugtenberg B, Berendsen W.
(
787763
)
|
J Biol Chem. 1996;271:3608-3614
Biosynthesis of inner core lipopolysaccharide in enteric bacteria: identification and characterization of a conserved phosphoheptose isomerase.
Brooke, J. S., and M. A. Valvano.
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| Sequences |
Amino acid
FASTA format
|
0001 MYQDLIRNEL NEAAETLANF LKDDANIHAI QRAAVLLADS FKAGGKVLSC GNGGSHCDAM HFAEELTGRY
0071 RENRPGYPAI AISDVSHISC VGNDFGFNDI FSRYVEAVGR EGDVLLGIST SGNSANVIKA IAAAREKGMK
0141 VITLTGKDGG KMAGTADIEI RVPHFGYADR IQEIHIKVIH ILIQLIEKEM VK
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 TCAAAAAGTC CTGGTCATAG CACCTGCCCG
-070 TACTTCTCGC TTTTGGCGGT ATCCGGTACA CTGCATTTTG TCTATTACAT TTATGCTGAA GGATATCCTC
0001 atgtaccagg atcttattcg taacgaactg aacgaagcgg cggaaacgct ggctaacttt ttaaaagatg
0071 acgccaatat tcacgccatt cagcgcgcgg cggtcctgtt agcagacagc tttaaagccg gtggcaaagt
0141 gctttcctgc ggcaacggcg gttcccattg cgacgctatg cactttgccg aagagttgac cggtcgctac
0211 cgtgaaaacc gtccgggcta cccggcgatt gctatttctg acgttagtca tatttcctgc gtcggtaatg
0281 atttcggttt caatgatatt ttctcccgct acgttgaagc ggtaggtcgc gaaggcgatg tactgctggg
0351 gatctccacc tccggtaact ctgcaaacgt gatcaaagcg atcgcagcgg cgcgtgagaa gggaatgaaa
0421 gtgatcaccc tgaccggtaa agacggcggc aaaatggctg gcacggcgga tatcgaaatt cgcgtaccgc
0491 actttggtta tgccgaccgc attcaggaga ttcacattaa agtgatccat atcctgatcc agttgattga
0561 aaaagagatg gttaagtaaG TCTGGCGTAG GCCGGATAAG ACGTTTACGC CGCATCCGGC ATTTGTGCGC
0631 TGATGCCTGA TGCGACGCTG ACGCGTCTTA TCATGCCTAC AAATCTGTA
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