|
PEC Original Annotations
|
|
Essentiality
|
|
Class
|
non-essential
|
|
References (PMID)
|
J Bacteriol. 1991;173(19):6294-6.
A mutation defining ultrainduction of the Escherichia coli gal operon.
Golding A, Weickert MJ, Tokeson JP, Garges S, Adhya S.
(
1655705
)
|
|
|
Deletion
|
16-2
(ND)
(LD)
,
OCL74
(D)
,
OCL74-4 (LD 16-2_CRS)
(D)
,
OCL74-5 (LD 16-2_P/O)
(D)
|
|
Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
galS
|
|
Related strains
|
|
Strains Search
|
Search strains by gene name:
galS
Search strains by all related name:
galS b2151 ECK2144 JW2138 mglD
|
General information (Go to Linear View: )
|
|
Gene Name
|
galS
|
|
Alternative name
|
b2151,ECK2144,JW2138,mglD
|
|
Location, Length
|
2,238,650 - 2,239,690
(
-
)
;
48.25
min
;
1041
(bp) ,
346
(aa)
|
|
Product
|
DNA-binding transcriptional repressor
|
|
Operon Name
|
galS
|
|
Note
|
mgl repressor, galactose operon inducer; GO_component: GO:0005737 - cytoplasm; GO_function: GO:0016564 - transcription repressor activity; GO_process: GO:0016052 - carbohydrate catabolic process; GO_process: GO:0006350 - transcription
|
|
Function
|
regulator; Degradation of small molecules: Carbon compounds
|
|
Gene Ontology
|
GO:0003677
;
DNA binding ( galS )
GO:0003700
;
transcription factor activity ( galS )
GO:0005622
;
intracellular ( galS )
GO:0006350
;
transcription ( galS )
GO:0006355
;
regulation of transcription, DNA-dependent ( galS )
|
|
PID
|
1788474
|
EC number
(KEGG Pathway)
|
|
|
Verified Protein Starts
(data
compiled from literature and appropriate citations are available from EcoGene)
|
|
EcoGene
|
galS
(
EG10365
)
|
|
Number of removed
|
0 aa cleaved
|
|
SWISS-PROT
(
Show details
[
2
more]
)
|
Entry name(Acc.no)
|
GALS_ECOLI
(
P25748
)
|
|
- Protein name
|
HTH-type transcriptional regulator galS
|
|
- Synonyms
|
Mgl repressor and galactose ultrainduction factor
|
|
- Gene name
|
Name=galS; OrderedLocusNames=b2151;
|
|
Homology Analysis
|
|
BLAST
|
|
Bacteria
|
|
GTOP
|
galS
(
homologous genes of other bacterias
)
|
|
PDB
(database updated :
2007.02.20
)
|
|
PSI-BLAST
|
Chain A, Purine Repressor-Hypoxanthine-Purf-Operator Complex
|
|
SWISS-PROT
(database updated :
2007.02.20
)
|
|
BLAST
|
HTH-type transcriptional regulator galS
|
|
PSI-BLAST
|
HTH-type transcriptional regulator galS
|
|
nr
(database updated :
2007.02.20
)
|
|
BLAST
|
DNA-binding transcriptional repressor [Escherichia coli K12]
|
|
Pfam 28.0
(database updated :
2015-05
)
|
|
Pfam
|
|
|
PROSITE
|
|
PROSITE
|
ASN_GLYCOSYLATION
CAMP_PHOSPHO_SITE
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
TYR_PHOSPHO_SITE
MYRISTYL
HTH_LACI_FAMILY
|
|
MMBR References
|
J Bacteriol. 1997;179:228-234
Functional characterization of roles of GalR and GalS as regulators of the gal regulon.
Geanacopoulos, M., and S. Adhya.
|
J Bacteriol. 1975;123(1):69-74.
Regulation of the Escherichia coli methylgalactoside transport system by gene mglD.
Robbins AR.
(
1095564
)
|
J Biol Chem. 1982;257:9030-9034
Identification of the mglA gene product in the beta-methylgalactoside transport system of Escherichia coli using plasmid DNA deletions generated in vitro.
Rotman, B., and R. Guzman.
|
Mol Microbiol. 1993;10(2):245-51.
The galactose regulon of Escherichia coli.
Weickert MJ, Adhya S.
(
7934815
)
|
| Sequences |
Amino acid
FASTA format
|
0001 MITIRDVARQ AGVSVATVSR VLNNSTLVSA DTREAVMKAV SELDYRPNAN AQALATQVSD TIGVVVMDVS
0071 DAFFGALVKA VDLVAQQHQK YVLIGNSYHE AEKERHAIEV LIRQRCNALI VHSKALSDDE LAQFMDNIPG
0141 MVLINRVVPG YAHRCVCLDN LSGARMATRM LLNNGHQRIG YLSSSHGIED DAMRKAGWMS ALKEQDIIPP
0211 ESWIGAGTPD MPGGEAAMVE LLGRNLQLTA VFAYNDNMAA GALTALKDNG IAIPLHLSII GFDDIPIARY
0281 TDPQLTTVRY PIASMAKLAT ELALQGAAGN IDPRASHCFM PTLVRRHSVA TRQNAAAITN STNQAM
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 tccattgctg tgactcgatt cacgaagtcc
-070 tgtattcagt gctgacaaaa tagccgccag caagcagtca tttactgcaa tctcataaca ggtagtgaat
0001 atgatcacca ttcgtgatgt agcgcgtcag gctggcgtct ctgtggcaac ggtttcccgg gtgctcaata
0071 acagcacgct ggtcagtgcc gacacgcgtg aagcagtaat gaaagccgtg agtgagctgg attatcggcc
0141 aaacgccaat gcccaggcgc tggcaactca ggttagcgac accattggcg tggtggtgat ggacgtttct
0211 gatgcgtttt tcggcgcgct ggtaaaagcg gtggatctgg tcgctcagca gcatcagaaa tacgtgctaa
0281 tcggcaatag ctatcatgaa gcggaaaaag agcgtcacgc cattgaggtg ttaattcgcc agcgttgtaa
0351 tgcgttgatt gttcactcaa aagcattgag tgacgatgaa ctggcgcaat ttatggataa cattcccggt
0421 atggtgttaa tcaaccgcgt tgtgccgggg tacgcccatc gttgcgtttg cctggataat ctcagcggtg
0491 cccgaatggc gacgcgcatg ttgctgaata acggtcatca acgtattggt tatctttctt ccagccacgg
0561 cattgaagat gacgccatgc gtaaagcagg ctggatgagt gcgttgaaag agcaggatat tattccgccg
0631 gaaagctgga ttggcgctgg tacgccggac atgccgggcg gtgaggcggc gatggttgaa ctgctggggc
0701 gcaatctaca acttaccgct gtatttgctt ataacgacaa tatggccgct ggcgcactga cagcattaaa
0771 agataatggc attgcgattc cgttacatct ctcaatcatc ggtttcgatg atattcccat cgcccgttac
0841 accgacccgc aattaacgac cgtgcgttat cccattgctt caatggcgaa attagccacc gaactggcct
0911 tgcagggggc agcaggcaat attgatcctc gtgccagcca ctgttttatg ccgacgttag tgcgtcgcca
0981 ttctgtcgca acacgccaga atgcggcggc gatcactaac tcaacaaatc aggcgatgta accgctttca
1051 atctgtgagt gatttcacag tatcttaaca atgtgatagc tatgattgca ccgttttaac gttgtaaccc
1121 gtatgtaaca gtgaataatc a
|
