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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
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Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
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Deletion
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16-2
(ND)
(LD)
,
OCL74
(D)
,
OCL74-4 (LD 16-2_CRS)
(D)
,
OCL74-5 (LD 16-2_P/O)
(D)
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|
Related gene (W3110 PEC)
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Gene Search
|
Search MG1655 PEC by gene name:
mglA
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Related strains
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Strains Search
|
Search strains by gene name:
mglA
Search strains by all related name:
mglA b2149 ECK2142 JW2136 mglP
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General information (Go to Linear View: )
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Gene Name
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mglA
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Alternative name
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b2149,ECK2142,JW2136,mglP
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Location, Length
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2,235,791 - 2,237,311
(
-
)
;
48.19
min
;
1521
(bp) ,
506
(aa)
|
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Product
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fused methyl-galactoside transporter subunits of ABC superfamily: ATP-binding components
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Operon Name
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mglBAC
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Note
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ATP-binding component of methyl-galactoside transport and galactose taxis; GO_component: GO:0005737 - cytoplasm; GO_process: GO:0016052 - carbohydrate catabolic process
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Function
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transport; Transport of small molecules: Carbohydrates, organic acids, alcohols
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Gene Ontology
|
GO:0000166
;
nucleotide binding ( mglA )
GO:0005351
;
sugar:hydrogen ion symporter activity ( mglA )
GO:0005524
;
ATP binding ( mglA )
GO:0005886
;
plasma membrane ( mglA )
GO:0006810
;
transport ( mglA )
GO:0008643
;
carbohydrate transport ( mglA )
GO:0015407
;
monosaccharide-transporting ATPase activity ( mglA )
GO:0016020
;
membrane ( mglA )
GO:0016787
;
hydrolase activity ( mglA )
GO:0016887
;
ATPase activity ( mglA )
GO:0017111
;
nucleoside-triphosphatase activity ( mglA )
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PID
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1788472
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EC number
(KEGG Pathway)
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SWISS-PROT
(
Show details
[
2
more]
)
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Entry name(Acc.no)
|
MGLA_ECOLI
(
P23199
;
P76442
)
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- Protein name
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Galactoside transport ATP-binding protein mglA.
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- Synonyms
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- Gene name
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Name=mglA; OrderedLocusNames=b2149, SF2234, S2363;
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MMBR References
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J Bacteriol. 1965;90(4):946-57.
Positive control of enzyme synthesis by gene C in the L-arabinose system.
Englesberg E, Irr J, Power J, Lee N.
(
5321403
)
|
J Bacteriol. 1983;153(1):408-15.
Characterization of the mgl operon of Escherichia coli by transposon mutagenesis and molecular cloning.
Harayama S, Bollinger J, Iino T, Hazelbauer GL.
(
6294056
)
|
Mol Gen Genet. 1991;229(3):453-9.
Nucleotide sequence and analysis of the mgl operon of Escherichia coli K12.
Hogg RW, Voelker C, Von Carlowitz I.
(
1719366
)
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Mol Gen Genet. 1984;197(1):175-81.
Mapping of markers in the gyrA-his region of Escherichia coli.
Middendorf A, Schweizer H, Vreemann J, Boos W.
(
6392823
)
|
J Bacteriol. 1976;126(2):999-1001.
Altered deoxyribonucleotide pools in P2 eductants of Escherichia coli K-12 due to deletion of the dcd gene.
Neuhard J, Thomassen E.
(
177407
)
|
J Bacteriol. 1974;117(2):509-16.
Isolation and complementation of mutants in galactose taxis and transport.
Ordal GW, Adler J.
(
4359647
)
|
J Biol Chem. 1982;257:9030-9034
Identification of the mglA gene product in the beta-methylgalactoside transport system of Escherichia coli using plasmid DNA deletions generated in vitro.
Rotman, B., and R. Guzman.
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Mol Gen Genet. 1987;208(1-2):247-53.
Sequence of the mglB gene from Escherichia coli K12: comparison of wild-type and mutant galactose chemoreceptors.
Scholle A, Vreemann J, Blank V, Nold A, Boos W, Manson MD.
(
3302609
)
|
Mol Gen Genet. 1983;191(3):401-6.
cir, a gene conferring resistance to colicin I maps between mgl and fpk on the Escherichia coli chromosome.
Boos W, Bantlow C, Benner D, Roller E.
(
6314091
)
|
Mol Gen Genet. 1981;184(3):508-18.
Mapping of mglB, the structural gene of the galactose-binding protein of Escherichia coli.
Boos W, Steinacher I, Engelhardt-Altendorf D.
(
6278261
)
|
J Bacteriol. 1981;147(3):920-4.
High-affinity arabinose transport mutants of Escherichia coli: isolation and gene location.
Clark AF, Hogg RW.
(
7024251
)
|
| Sequences |
Amino acid
FASTA format
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0001 MVSSTTPSSG EYLLEMSGIN KSFPGVKALD NVNLKVRPHS IHALMGENGA GKSTLLKCLF GIYQKDSGTI
0071 LFQGKEIDFH SAKEALENGI SMVHQELNLV LQRSVMDNMW LGRYPTKGMF VDQDKMYRET KAIFDELDID
0141 IDPRARVGTL SVSQMQMIEI AKAFSYNAKI VIMDEPTSSL TEKEVNHLFT IIRKLKERGC GIVYISHKME
0211 EIFQLCDEVT VLRDGQWIAT EPLAGLTMDK IIAMMVGRSL NQRFPDKENK PGEVILEVRN LTSLRQPSIR
0281 DVSFDLHKGE ILGIAGLVGA KRTDIVETLF GIREKSAGTI TLHGKQINNH NANEAINHGF ALVTEERRST
0351 GIYAYLDIGF NSLISNIRNY KNKVGLLDNS RMKSDTQWVI DSMRVKTPGH RTQIGSLSGG NQQKVIIGRW
0421 LLTQPEILML DEPTRGIDVG AKFEIYQLIA ELAKKGKGII IISSEMPELL GITDRILVMS NGLVSGIVDT
0491 KTTTQNEILR LASLHL
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Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 cgtagataaa gacaacctgg ctgaattcag
-070 caagaaataa gactgattgg gcgcagtcta ttactgcgcc cttattgtat ggccaacaag gtaaaattat
0001 atggtcagct caacgactcc gtcctccggg gaatacttgt tggaaatgag cggtatcaac aagtcctttc
0071 ctggtgttaa ggcacttgat aacgttaatt taaaagtccg gccacattct atccatgcat taatggggga
0141 aaacggtgca ggaaaatcga cattattaaa atgcctgttt ggtatttatc aaaaagactc cggcaccatt
0211 ttattccagg gtaaagagat cgatttccat tctgcaaaag aagccctgga aaatggtatt tcgatggtac
0281 accaggagtt aaacctggta ttacaacgtt cggtgatgga taacatgtgg ctggggcgat atcccaccaa
0351 aggcatgttt gtcgatcagg acaaaatgta ccgcgaaacc aaagcgattt ttgacgaact ggatattgat
0421 atcgatccgc gtgcgcgcgt cggcacatta tccgtttcgc aaatgcagat gatcgaaatc gccaaagcgt
0491 tttcctataa cgcgaaaatt gtgattatgg atgaaccgac ttcttcgtta accgaaaaag aggtcaatca
0561 tctgttcact attattcgta aattaaaaga gcgcggctgc ggtattgttt atatctcgca taaaatggaa
0631 gaaatcttcc agttatgtga tgaagttacc gtattgcgcg acggtcagtg gatcgccacc gaaccgctgg
0701 caggactgac gatggacaag atcatcgcca tgatggttgg gcgttctctt aaccagcgtt tccctgacaa
0771 agaaaacaaa ccgggcgaag tcatcctcga ggtacgtaac ctgacgtcac tgcgccagcc gtcgattcgc
0841 gatgtctcgt ttgatctgca taaaggggag atcctcggta ttgccggtct ggtgggggcg aaacgtaccg
0911 atattgttga gacgttattt ggtattcgcg agaaatcggc tggcaccata acgttgcacg gcaaacagat
0981 caataaccat aatgccaacg aagccataaa ccatggattt gcactggtaa ctgaggagcg ccgctcaacg
1051 ggaatttatg cctatctgga tattggtttt aactcgttaa tttccaatat tcgcaactac aaaaataaag
1121 ttggtttact ggataactcg cggatgaaaa gcgataccca gtgggtgatt gattcgatgc gggtaaaaac
1191 gccgggtcat cggacgcaaa ttggttcgct ctccggtggt aatcagcaaa aggtgattat tggtcgctgg
1261 ctactaacgc aaccagaaat attaatgctc gatgaaccga cgcgcggtat tgatgtcggg gcgaagtttg
1331 aaatttatca gttaattgcc gaactggcga agaaaggcaa ggggattatt attatctcct ctgaaatgcc
1401 tgagttgtta gggataacag accgtattct ggtcatgagc aatggtctcg tttccggaat tgtcgataca
1471 aaaacaacaa cgcaaaacga aattctgcgt cttgcgtctt tgcaccttta agattagggg cttcccatga
1541 gtgcgttaaa taagaaaagt tttcttactt acctgaaaga gggcggtatt tacgtcgttc ttttagtttt
1611 gctggcgatt a
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