MG1655
W3110
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Gene Report : udk
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)  
     Deletion 16-1-2 (LD)  ,  DE(sbcB-rfb)202  ,  OCL74-2,75-5 (LD 16-1-2_CRS) (D)  ,  OCL74-2,75-6 (LD 16-1-2_P/O) (D)  ,  OCL74-3 (D)  
Related gene (W3110 PEC)
     Gene Search Search MG1655 PEC by gene name:  udk
Related strains
     Strains Search Search strains by gene name:  udk   Search strains by all related name:  udk b2066 ECK2060 JW2051

General information  (Go to Linear View:)
 Gene Name udk  
 Alternative name b2066,ECK2060,JW2051  
 Location, Length 2,140,331 - 2,140,972 (  -  ) ;   46.13 min ; 642 (bp) ,   213 (aa) Go to Linear View
 Product uridine/cytidine kinase  
 Operon Name udk-dcd  
 Note GO_process: GO:0015949 - nucleobase, nucleoside and nucleotide interconversion  
 Function enzyme; Central intermediary metabolism: Nucleotide interconversions  
 Gene Ontology GO:0000166 ; nucleotide binding ( udk )
GO:0004849 ; uridine kinase activity ( udk )
GO:0005524 ; ATP binding ( udk )
GO:0005737 ; cytoplasm ( udk )
GO:0008152 ; metabolic process ( udk )
GO:0008655 ; pyrimidine salvage ( udk )
GO:0016301 ; kinase activity ( udk )
GO:0016740 ; transferase activity ( udk )
GO:0016773 ; phosphotransferase activity, alcohol group as acceptor ( udk )
 PID 87082034  
 EC number
  (KEGG Pathway)
 
2.7.1.48  
SWISS-PROT  ( Show details )
  botton Entry name(Acc.no) URK_ECOLI ( P31218 ; P78085; Q8X7L3 )
    -  Protein name Uridine kinase  
    -  Synonyms EC 2.7.1.48, Uridine monophosphokinase, Cytidine monophosphokinase  
    -  Gene name OrderedLocusNames=b2066, c2593, z3234, ECs2873, SF2130, S2254;  

 Linear View (Whole Mode)
View Location
   2130.0  –  2155.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP udk (  homologous genes of other bacterias  )  
    PDB     (database updated : 2007.02.20 )
         PSI-BLAST Chain A, Crystal Structure Of Human Uridine-Cytidine Kinase 2 Complexed With A Feedback-Inhibitor, Ctp  
    SWISS-PROT     (database updated : 2007.02.20 )
         BLAST Uridine kinase (Uridine monophosphokinase) (Cytidine monophosphokinase)  
         PSI-BLAST Adenylate kinase
    nr     (database updated : 2007.02.20 )
         BLAST uridine kinase [Escherichia coli CFT073]  
Pfam 28.0   (database updated : 2015-05 )
    Pfam
PROSITE
    PROSITE ASN_GLYCOSYLATION    CAMP_PHOSPHO_SITE    PKC_PHOSPHO_SITE    CK2_PHOSPHO_SITE    MYRISTYL    ATP_GTP_A     

Other Cross-Reference
    COG COG0572F 
    EcoCyc udk 

MMBR References
J Bacteriol. 1983;154(1):72-5.
Mapping of the gene for cytidine deaminase (cdd) in Escherichia coli K-12.
Josephsen J, Hammer-Jespersen K, Hansen TD. ( 6339482 )
J Bacteriol. 1976;126(2):999-1001.
Altered deoxyribonucleotide pools in P2 eductants of Escherichia coli K-12 due to deletion of the dcd gene.
Neuhard J, Thomassen E. ( 177407 )
J Bacteriol. 1993;175(17):5742-3.
Location of the udk gene on the physical map of Escherichia coli.
Neuhard J, Tarpo L. ( 8366067 )

Sequences
Amino acid
FASTA format
0001 MTDQSHQCVI IGIAGASASG KSLIASTLYR ELREQVGDEH IGVIPEDCYY KDQSHLSMEE RVKTNYDHPS 
0071 AMDHSLLLEH LQALKRGSAI DLPVYSYVEH TRMKETVTVE PKKVIILEGI LLLTDARLRD ELNFSIFVDT 
0141 PLDICLMRRI KRDVNERGRS MDSVMAQYQK TVRPMFLQFI EPSKQYADII VPRGGKNRIA IDILKAKISQ 
0211 FFE

Nucleotide
FASTA format

View sequence out neighbor 100bp
-100                                             ctattcgact ggtatcagac ggatgaaatc 
-070 cctataattg ccgcgtttgg cgcttcgtcg cccccttcct aacatccagg ttaatcaggt cgctaaatat 
0001 atgactgatc agtctcatca gtgcgtcatt atcggtatcg ctggcgcatc ggcttccggc aagagtctta 
0071 ttgccagtac cctttatcgt gaattgcgtg agcaagtcgg tgatgaacac atcggcgtaa ttcccgaaga 
0141 ctgctattac aaagatcaaa gccatctgtc gatggaagaa cgcgttaaga ccaactacga ccatcccagc 
0211 gcgatggatc acagtctgct gcttgagcat ttacaagcgt tgaaacgcgg ctcggcaatt gacctgccgg 
0281 tttacagcta tgttgaacat acgcgtatga aagaaacggt gacggttgag ccgaagaagg tcatcattct 
0351 cgaaggcatt ttgttgctga cggatgcgcg tttgcgtgac gaacttaact tctccatttt cgttgatacc 
0421 ccgctggata tctgcctgat gcgccgcatc aagcgtgacg ttaacgagcg tgggcgttca atggattcag 
0491 tgatggcgca atatcaaaaa accgtgcgcc cgatgttcct gcaattcatt gagccttcta aacaatatgc 
0561 ggacattatc gtgccgcgcg gcgggaaaaa ccgcatcgcg atcgatatat tgaaagcgaa aataagtcag 
0631 ttctttgaat aagcttgata aattgtgtac cgttcagtga taacctagta tgcccttgac gtaattggcg 
0701 ttaagggagt gatgcgcgaa aggagaaaat gccatgcgtc tg