MG1655
W3110
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Gene Report : tyrP
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
     Deletion OCL78 (D)  
Related gene (W3110 PEC)
     Gene Search Search MG1655 PEC by gene name:  tyrP
Related strains
     Strains Search Search strains by gene name:  tyrP   Search strains by all related name:  tyrP b1907 ECK1906 JW1895

General information  (Go to Linear View:)
 Gene Name tyrP  
 Alternative name b1907,ECK1906,JW1895  
 Location, Length 1,987,705 - 1,988,916 (  +  ) ;   42.84 min ; 1212 (bp) ,   403 (aa) Go to Linear View
 Product tyrosine transporter  
 Operon Name tyrP  
 Note tyrosine-specific transport system; GO_component: GO:0009274 - peptidoglycan-based cell wall; GO_component: GO:0019866 - organelle inner membrane; GO_process: GO:0006571 - tyrosine biosynthetic process  
 Function transport; Transport of small molecules: Amino acids, amines  
 Gene Ontology GO:0005886 ; plasma membrane ( tyrP )
GO:0006810 ; transport ( tyrP )
GO:0006865 ; amino acid transport ( tyrP )
GO:0016020 ; membrane ( tyrP )
GO:0016021 ; integral to membrane ( tyrP )
 PID 1788218  
 EC number
  (KEGG Pathway)
 
 
SWISS-PROT  ( Show details [ 2 more] )
  botton Entry name(Acc.no) TYRP_ECOLI ( P18199 ; P76309 )
    -  Protein name Tyrosine-specific transport protein  
    -  Synonyms Tyrosine permease  
    -  Gene name Name=tyrP; OrderedLocusNames=b1907, SF1953, S2046;  

 Linear View (Whole Mode)
View Location
   1975.0  –  2000.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP tyrP (  homologous genes of other bacterias  )  
    PDB     (database updated : 2007.02.20 )
        PSI-BLAST  
    SWISS-PROT     (database updated : 2007.02.20 )
         BLAST Tyrosine-specific transport protein (Tyrosine permease)  
         PSI-BLAST High-affinity glutamine permease
    nr     (database updated : 2007.02.20 )
         BLAST tyrosine transporter [Escherichia coli K12]  
Pfam 28.0   (database updated : 2015-05 )
    Pfam
PROSITE
    PROSITE ASN_GLYCOSYLATION    GLYCOSAMINOGLYCAN    PKC_PHOSPHO_SITE    CK2_PHOSPHO_SITE    MYRISTYL    AROMATIC_AA_PERMEASE     

Other Cross-Reference
    COG COG0814E 
    EcoCyc tyrP 

MMBR References
J Bacteriol. 1986;167(2):556-61.
Molecular analysis of the promoter operator region of the Escherichia coli K-12 tyrP gene.
Kasian PA, Davidson BE, Pittard J. ( 3525516 )
J Bacteriol. 1984;160(1):175-83.
Construction of a tyrP-lac operon fusion strain and its use in the isolation and analysis of mutants derepressed for tyrP expression.
Kasian PA, Pittard J. ( 6090410 )
J Bacteriol. 1980;143(1):1-7.
Isolation and characterization of an Escherichia coli K-12 mutant defective in tyrosine- and phenylalanine-specific transport systems.
Whipp MJ, Halsall DM, Pittard AJ. ( 6995422 )
J Bacteriol. 1984;160(1):169-74.
Cloning of the tyrP gene and further characterization of the tyrosine-specific transport system in Escherichia coli K-12.
Wookey PJ, Pittard J, Forrest SM, Davidson BE. ( 6090409 )
J Bacteriol. 1988;170(10):4946-9.
DNA sequence of the gene (tyrP) encoding the tyrosine-specific transport system of Escherichia coli.
Wookey PJ, Pittard AJ. ( 3049553 )

Sequences
Amino acid
FASTA format
0001 MKNRTLGSVF IVAGTTIGAG MLAMPLAAAG VGFSVTLILL IGLWALMCYT ALLLLEVYQH VPADTGLGTL 
0071 AKRYLGRYGQ WLTGFSMMFL MYALTAAYIS GAGELLASSI SDWTGISMSA TAGVLLFTFV AGGVVCVGTS 
0141 LVDLFNRFLF SAKIIFLVVM LVLLLPHIHK VNLLTLPLQQ GLALSAIPVI FTSFGFHGSV PSIVSYMDGN 
0211 IRKLRWVFII GSAIPLVAYI FWQVATLGSI DSTTFMGLLA NHAGLNGLLQ ALREMVASPH VELAVHLFAD 
0281 LALATSFLGV ALGLFDYLAD LFQRSNTVGG RLQTGAITFL PPLAFALFYP RGFVMALGYA GVALAVLALI 
0351 IPSLLTWQSR KHNPQAGYRV KGGRPALVVV FLCGIAVIGV QFLIAAGLLP EVG

Nucleotide
FASTA format

View sequence out neighbor 100bp
-100                                             ATATTTACAC CATATGTAAC GTCGGTTTGA 
-070 CGAAGCAGCC GTTATGCCTT AACCTGCGCC GCAGATATCA CTCATAAAGA TCGTCAGGAC AGAAGAAAGC 
0001 gtgaaaaaca gaaccctggg aagtgttttt atcgtggcgg gaaccacaat tggcgcaggc atgctggcaa 
0071 tgccgctggc tgcggccggt gttggtttta gcgttacgtt aatcttgttg attgggcttt gggcgttgat 
0141 gtgctacacg gcgctattac tgctggaggt gtaccagcat gttccggcag ataccggtct gggcacgctg 
0211 gcaaaacgct atctgggacg ctacggtcaa tggctgacgg gcttcagtat gatgttctta atgtatgctc 
0281 tgactgcggc atacatcagc ggtgccggtg aattgttggc ctccagcatc agcgactgga caggtatttc 
0351 tatgtcggca accgctggcg tgctgttgtt cacttttgtt gccggtggcg tggtttgtgt cggaacttca 
0421 ctggtcgatt tatttaaccg ttttctgttc agcgccaaga ttatttttct ggtggtaatg ctggtactac 
0491 tgctgccgca tattcacaaa gtgaatcttt taaccctgcc gttgcaacag gggctggctc tgtctgcaat 
0561 cccggtgatt tttacgtcgt ttggttttca cggtagcgtg ccgagtattg tcagctatat ggatggcaac 
0631 attcgtaagc tacgctgggt gtttataatc ggtagtgcga tccccctggt ggcatatatt ttctggcagg 
0701 tggcgacgct tggcagcatt gattcaacaa cctttatggg attgctggct aatcatgctg gattaaacgg 
0771 gctgttacag gcgttacgcg aaatggtggc ctctccgcat gttgagctgg cagtgcattt atttgctgat 
0841 ttagccctcg ccacgtcatt tctcggcgtt gcgttaggct tatttgatta tctggctgat ttatttcagc 
0911 gttcaaatac cgttggtgga cggttgcaaa ctggtgcaat tacgtttctg ccgccgttgg cgtttgcact 
0981 gttttatcca cgaggatttg tgatggcgct gggttacgcc ggtgtggcgc tggcggtact ggcattgatt 
1051 atcccttcgc tgttgacctg gcaaagcaga aagcacaatc ctcaggcggg ttaccgggtc aaaggtggtc 
1121 gtccggcgct ggtggtggtg tttctctgtg gtattgctgt gattggcgtg caatttttga ttgcggcagg 
1191 gttgttacca gaagtggggt gaTCAGATAG CCTCAAATTC CTTATTGGGT GCCAGAATTA ACGCTGACAC 
1261 CCAATTTGGC CTCTTAATGC AGGCAGCACT GCTTAAATTT CTTACCACTA CC