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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
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Deletion
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DE(eda-zwf)15
,
OCL81-7
(D)
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Related gene (W3110 PEC)
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Gene Search
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Search MG1655 PEC by gene name:
edd
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Related strains
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Strains Search
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Search strains by gene name:
edd
Search strains by all related name:
edd b1851 ECK1852 JW1840
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General information (Go to Linear View: )
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Gene Name
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edd
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Alternative name
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b1851,ECK1852,JW1840
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Location, Length
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1,930,817 - 1,932,628
(
-
)
;
41.62
min
;
1812
(bp) ,
603
(aa)
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Product
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6-phosphogluconate dehydratase
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Operon Name
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edd-eda
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Note
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GO_process: GO:0009255 - Entner-Doudoroff pathway
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Function
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enzyme; Central intermediary metabolism: Entner-Douderoff
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Gene Ontology
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GO:0003824
;
catalytic activity ( edd )
GO:0004456
;
phosphogluconate dehydratase activity ( edd )
GO:0008152
;
metabolic process ( edd )
GO:0009255
;
Entner-Doudoroff pathway ( edd )
GO:0016829
;
lyase activity ( edd )
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PID
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1788157
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EC number
(KEGG Pathway)
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4.2.1.12
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SWISS-PROT
(
Show details
[
1
more]
)
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Entry name(Acc.no)
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EDD_ECOLI
(
P25530
)
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- Protein name
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Phosphogluconate dehydratase
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- Synonyms
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EC 4.2.1.12, 6-phosphogluconate dehydratase
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- Gene name
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Name=edd; OrderedLocusNames=b1851, z2903, ECs2561;
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MMBR References
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J Bacteriol. 1992;174:4638-4646
Molecular characterization of the Entner-Doudoroff pathway in Escherichia coli: sequence analysis and localization of promoters for the edd-eda operon.
Egan, S. E., R. Fliege, S. Tong, A. Shibata, R. E. Wolf, and T. Conway.
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J Bacteriol. 1971;108(3):1277-83.
2-keto-3-deoxygluconate 6-phosphate aldolase mutants of Escherichia coli.
Fradkin JE, Fraenkel DG.
(
4945194
)
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Genetics 1972;71:481-489
Deletion mapping of zwf, the gene for a constitutive enzyme, glucose 6-phosphate dehydrogenase, in Escherichia coli.
Fraenkel, D., and S. Banerjee.
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J Biol Chem. 1988;263:11683-11691
The complete amino acid sequence and identification of the active-site arginine peptide of Escherichia coli 2-keto-4-hydroxyglutarate aldolase.
Vlahos, C. J., and E. E. Dekker.
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| Sequences |
Amino acid
FASTA format
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0001 MNPQLLRVTN RIIERSRETR SAYLARIEQA KTSTVHRSQL ACGNLAHGFA ACQPEDKASL KSMLRNNIAI
0071 ITSYNDMLSA HQPYEHYPEI IRKALHEANA VGQVAGGVPA MCDGVTQGQD GMELSLLSRE VIAMSAAVGL
0141 SHNMFDGALF LGVCDKIVPG LTMAALSFGH LPAVFVPSGP MASGLPNKEK VRIRQLYAEG KVDRMALLES
0211 EAASYHAPGT CTFYGTANTN QMVVEFMGMQ LPGSSFVHPD SPLRDALTAA AARQVTRMTG NGNEWMPIGK
0281 MIDEKVVVNG IVALLATGGS TNHTMHLVAM ARAAGIQINW DDFSDLSDVV PLMARLYPNG PADINHFQAA
0351 GGVPVLVREL LKAGLLHEDV NTVAGFGLSR YTLEPWLNNG ELDWREGAEK SLDSNVIASF EQPFSHHGGT
0421 KVLSGNLGRA VMKTSAVPVE NQVIEAPAVV FESQHDVMPA FEAGLLDRDC VVVVRHQGPK ANGMPELHKL
0491 MPPLGVLLDR CFKIALVTDG RLSGASGKVP SAIHVTPEAY DGGLLAKVRD GDIIRVNGQT GELTLLVDEA
0561 ELAAREPHIP DLSASRVGTG RELFSALREK LSGAEQGATC ITF
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Nucleotide
FASTA format
View sequence out neighbor 100bp
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-100 tgccctatga gctccggtta caggcgtttc
-070 agtcataaat cctctgaatg aaacgcgttg tgaatcatcc tgctctgaca actcaatttc aggagccttt
0001 atgaatccac aattgttacg cgtaacaaat cgaatcattg aacgttcgcg cgagactcgc tctgcttatc
0071 tcgcccggat agaacaagcg aaaacttcga ccgttcatcg ttcgcagttg gcatgcggta acctggcaca
0141 cggtttcgct gcctgccagc cagaagacaa agcctctttg aaaagcatgt tgcgtaacaa tatcgccatc
0211 atcacctcct ataacgacat gctctccgcg caccagcctt atgaacacta tccagaaatc attcgtaaag
0281 ccctgcatga agcgaatgcg gttggtcagg ttgcgggcgg tgttccggcg atgtgtgatg gtgtcaccca
0351 ggggcaggat ggaatggaat tgtcgctgct aagccgcgaa gtgatagcga tgtctgcggc ggtggggctg
0421 tcccataaca tgtttgatgg tgctctgttc ctcggtgtgt gcgacaagat tgtcccgggt ctgacgatgg
0491 cagccctgtc gtttggtcat ttgcctgcgg tgtttgtgcc gtctggaccg atggcaagcg gtttgccaaa
0561 taaagaaaaa gtgcgtattc gccagcttta tgccgaaggt aaagtggacc gcatggcctt actggagtca
0631 gaagccgcgt cttaccatgc gccgggaaca tgtactttct acggtactgc caacaccaac cagatggtgg
0701 tggagtttat ggggatgcag ttgccaggct cttcttttgt tcatccggat tctccgctgc gcgatgcttt
0771 gaccgccgca gctgcgcgtc aggttacacg catgaccggt aatggtaatg aatggatgcc gatcggtaag
0841 atgatcgatg agaaagtggt ggtgaacggt atcgttgcac tgctggcgac cggtggttcc actaaccaca
0911 ccatgcacct ggtggcgatg gcgcgcgcgg ccggtattca gattaactgg gatgacttct ctgacctttc
0981 tgatgttgta ccgctgatgg cacgtctcta cccgaacggt ccggccgata ttaaccactt ccaggcggca
1051 ggtggcgtac cggttctggt gcgtgaactg ctcaaagcag gcctgctgca tgaagatgtc aatacggtgg
1121 caggttttgg tctgtctcgt tatacccttg aaccatggct gaataatggt gaactggact ggcgggaagg
1191 ggcggaaaaa tcactcgaca gcaatgtgat cgcttccttc gaacaacctt tctctcatca tggtgggaca
1261 aaagtgttaa gcggtaacct gggccgtgcg gttatgaaaa cctctgccgt gccggttgag aaccaggtga
1331 ttgaagcgcc agcggttgtt tttgaaagcc agcatgacgt tatgccggcc tttgaagcgg gtttgctgga
1401 ccgcgattgt gtcgttgttg tccgtcatca ggggccaaaa gcgaacggaa tgccagaatt acataaactc
1471 atgccgccac ttggtgtatt attggaccgg tgtttcaaaa ttgcgttagt taccgatgga cgactctccg
1541 gcgcttcagg taaagtgccg tcagctatcc acgtaacacc agaagcctac gatggcgggc tgctggcaaa
1611 agtgcgcgac ggggacatca ttcgtgtgaa tggacagaca ggcgaactga cgctgctggt agacgaagcg
1681 gaactggctg ctcgcgaacc gcacattcct gacctgagcg cgtcacgcgt gggaacagga cgtgaattat
1751 tcagcgcctt gcgtgaaaaa ctgtccggtg ccgaacaggg cgcaacctgt atcacttttt aagacgacaa
1821 atttgtaatc aggcgagaga aaactctgat gaaaaactgg aaaacaagtg cagaatcaat cctgaccacc
1891 ggcccggttg taccggttat cg
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