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PEC Original Annotations
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Essentiality
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Class
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essential
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References (PMID)
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Proc Natl Acad Sci U S A. 1994;91(10):4249-53.
Ribosome recycling factor (ribosome releasing factor) is essential for bacterial growth.
Janosi L, Shimizu I, Kaji A.
(
8183897
)
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Deletion
|
OCR33,34-1
(D)
,
OCR33,34-2
(D)
,
OCR33,35-4 (AK4-2 / BK5-2)
(D)
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Related gene (W3110 PEC)
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Gene Search
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Search MG1655 PEC by gene name:
frr
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Related strains
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Strains Search
|
Search strains by gene name:
frr
Search strains by all related name:
frr b0172 ECK0171 JW0167 rrf
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General information (Go to Linear View: )
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Gene Name
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frr
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Alternative name
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b0172,ECK0171,JW0167,rrf
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Location, Length
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192,872 - 193,429
(
+
)
;
4.16
min
;
558
(bp) ,
185
(aa)
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Product
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ribosome recycling factor
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Operon Name
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frr
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Note
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ribosome releasing factor; GO_component: GO:0005737 - cytoplasm; GO_process: GO:0006412 - translation; GO_process: GO:0009386 - translational attenuation
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Function
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factor; Proteins - translation and modification
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Gene Ontology
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GO:0005737
;
cytoplasm ( frr )
GO:0006412
;
translation ( frr )
GO:0006415
;
translational termination ( frr )
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PID
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1786368
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EC number
(KEGG Pathway)
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Verified Protein Starts
(data
compiled from literature and appropriate citations are available from EcoGene)
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EcoGene
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frr
(
EG10335
)
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Number of removed
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0 aa cleaved
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SWISS-PROT
(
Show details
)
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Entry name(Acc.no)
|
RRF_ECOLI
(
P16174
)
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- Protein name
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Ribosome recycling factor
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- Synonyms
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Ribosome releasing factor, RRF
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- Gene name
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OrderedLocusNames=b0172, c0208, z0183, ECs0174, SF0162, S0165;
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MMBR References
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EMBO J. 1998;17:808-816
Ribosome release factor RF4 and termination factor RF3 are involved in dissociation of peptidyl-tRNA from the ribosome.
Heurgue-Hamard, V., R. Karimi, L. Mora, J. MacDougall, C. Leboeuf, G. Grentzmann, M. Ehrenberg, and R. H. Buckingham.
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J Biol Chem. 1989;264:20054-20059
Molecular cloning and expression of ribosome releasing factor.
Ichikawa, S., and A. Kaji.
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J Bacteriol. 1989;171(7):3689-95.
Localization of the ribosome-releasing factor gene in the Escherichia coli chromosome.
Ichikawa S, Ryoji M, Siegfried Z, Kaji A.
(
2661533
)
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Proc Natl Acad Sci U S A. 1994;91:4249-4253
Ribosome recycling factor (ribosome releasing factor) is essential for bacterial growth.
Janosi, L., I. Shimizu, and A. Kaji.
|
J Bacteriol. 1991;173(16):5181-7.
Identification of the promoter region of the ribosome-releasing factor cistron (frr).
Shimizu I, Kaji A.
(
1860827
)
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| Sequences |
Amino acid
FASTA format
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0001 MISDIRKDAE VRMDKCVEAF KTQISKIRTG RASPSLLDGI VVEYYGTPTP LRQLASVTVE DSRTLKINVF
0071 DRSMSPAVEK AIMASDLGLN PNSAGSDIRV PLPPLTEERR KDLTKIVRGE AEQARVAVRN VRRDANDKVK
0141 ALLKDKEISE DDDRRSQDDV QKLTDAAIKK IEAALADKEA ELMQF
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Nucleotide
FASTA format
View sequence out neighbor 100bp
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-100 ACGATTACCC GTAATATGTT TAATCAGGGC
-070 TATACTTAGC ACACTTCCAC TGTGTGTGAC TGTCTGGTCT GACTGAGACA AGTTTTCAAG GATTCGTAAC
0001 gtgattagcg atatcagaaa agatgctgaa gtacgcatgg acaaatgcgt agaagcgttc aaaacccaaa
0071 tcagcaaaat acgcacgggt cgtgcttctc ccagcctgct ggatggcatt gtcgtggaat attacggcac
0141 gccgacgccg ctgcgtcagc tggcaagcgt aacggtagaa gattcccgta cactgaaaat caacgtgttt
0211 gatcgttcaa tgtctccggc cgttgaaaaa gcgattatgg cgtccgatct tggcctgaac ccgaactctg
0281 cgggtagcga catccgtgtt ccgctgccgc cgctgacgga agaacgtcgt aaagatctga ccaaaatcgt
0351 tcgtggtgaa gcagaacaag cgcgtgttgc agtacgtaac gtgcgtcgtg acgcgaacga caaagtgaaa
0421 gcactgttga aagataaaga gatcagcgaa gacgacgatc gccgttctca ggacgatgta cagaaactga
0491 ctgatgctgc aatcaagaaa attgaagcgg cgctggcaga caaagaagca gaactgatgc agttctgaTT
0561 TCTTGAACGA CAAAAACGCC GCTCAGTAGA TCCTTGCGGA TCGGCTGGCG GCGTTTTGCT TTTTATTCTG
0631 TCTCAACTCT GGATGTTTCA TGAAGCAA
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