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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
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Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
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Deletion
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OCL85
(D)
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Related gene (W3110 PEC)
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Gene Search
|
Search MG1655 PEC by gene name:
chbC
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Related strains
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Strains Search
|
Search strains by gene name:
chbC
Search strains by all related name:
chbC b1737 celB ECK1735 f452 JW1726
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General information (Go to Linear View: )
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Gene Name
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chbC
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Alternative name
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b1737,celB,ECK1735,f452,JW1726
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Location, Length
|
1,817,880 - 1,819,238
(
-
)
;
39.18
min
;
1359
(bp) ,
452
(aa)
|
|
Product
|
N,N'-diacetylchitobiose-specific enzyme IIC component of PTS
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Operon Name
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chbBCARFG
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Note
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PEP-dependent phosphotransferase enzyme II for cellobiose, arbutin, and salicin; GO_component: GO:0009274 - peptidoglycan-based cell wall; GO_component: GO:0019866 - organelle inner membrane; GO_process: GO:0016052 - carbohydrate catabolic process
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Function
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enzyme; Transport of small molecules: Carbohydrates, organic acids, alcohols
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Gene Ontology
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GO:0005351
;
sugar:hydrogen ion symporter activity ( chbC )
GO:0005886
;
plasma membrane ( chbC )
GO:0006810
;
transport ( chbC )
GO:0008643
;
carbohydrate transport ( chbC )
GO:0008982
;
protein-N(PI)-phosphohistidine-sugar phosphotransferase activity ( chbC )
GO:0009401
;
phosphoenolpyruvate-dependent sugar phosphotransferase system ( chbC )
GO:0016020
;
membrane ( chbC )
GO:0016021
;
integral to membrane ( chbC )
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PID
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1788032
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EC number
(KEGG Pathway)
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2.7.1.69
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SWISS-PROT
(
Show details
[
2
more]
)
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Entry name(Acc.no)
|
PTCC_ECOLI
(
P17334
;
P76212; P76907; P77332
)
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- Protein name
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PTS system, N,N'-diacetylchitobiose-specific IIC component
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- Synonyms
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EIIC-Chb, N,N'-diacetylchitobiose-permease IIC component, Phosphotransferase enzyme II, C component
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- Gene name
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Name=chbC; Synonyms=celB; OrderedLocusNames=b1737;
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Homology Analysis
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BLAST
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Bacteria
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GTOP
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chbC
(
homologous genes of other bacterias
)
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PDB
(database updated :
2007.02.20
)
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PSI-BLAST
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SWISS-PROT
(database updated :
2007.02.20
)
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BLAST
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N,N'-diacetylchitobiose permease IIC component
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PSI-BLAST
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PTS system lactose-specific EIICB component
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nr
(database updated :
2007.02.20
)
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BLAST
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N,N'-diacetylchitobiose-specific enzyme IIC component of PTS [Escherichia coli K12]
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Pfam 28.0
(database updated :
2015-05
)
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Pfam
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PROSITE
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PROSITE
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ASN_GLYCOSYLATION
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
MYRISTYL
ATP_GTP_A
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MMBR References
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Proc Natl Acad Sci U S A. 1997;94:14367-14371
Wild-type Escherichia coli grows on the chitin disaccharide, N,N'-diacetylchitobiose, by expressing the cel operon.
Keyhani, N. O., and S. Roseman.
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Mol Biol Evol. 1984;1:171-182
Directed evolution of cellobiose utilization in Escherichia coli K12.
Kricker, M., and B. G. Hall.
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Genetics 1987;115:419-429
Biochemical genetics of the cryptic gene system for cellobiose utilization in Escherichia coli K12.
Kricker, M., and B. G. Hall.
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Genetics 1990;124:455-471
Characterization and nucleotide sequence of the cryptic cel operon of E. coli K12.
Parker, L. L., and B. G. Hall.
|
Res Microbiol. 1990;141(9):1061-7.
The cellobiose permease of Escherichia coli consists of three proteins and is homologous to the lactose permease of Staphylococcus aureus.
Reizer J, Reizer A, Saier MH Jr.
(
2092358
)
|
| Sequences |
Amino acid
FASTA format
|
0001 MSNVIASLEK VLLPFAVKIG KQPHVNAIKN GFIRLMPLTL AGAMFVLINN VFLSFGEGSF FYSLGIRLDA
0071 STIETLNGLK GIGGNVYNGT LGIMSLMAPF FIGMALAEER KVDALAAGLL SVAAFMTVTP YSVGEAYAVG
0141 ANWLGGANII SGIIIGLVVA EMFTFIVRRN WVIKLPDSVP ASVSRSFSAL IPGFIILSVM GIIAWALNTW
0211 GTNFHQIIMD TISTPLASLG SVVGWAYVIF VPLLWFFGIH GALALTALDN GIMTPWALEN IATYQQYGSV
0281 EAALAAGKTF HIWAKPMLDS FIFLGGSGAT LGLILAIFIA SRRADYRQVA KLALPSGIFQ INEPILFGLP
0351 IIMNPVMFIP FVLVQPILAA ITLAAYYMGI IPPVTNIAPW TMPTGLGAFF NTNGSVAALL VALFNLGIAT
0421 LIYLPFVVVA NKAQNAIDKE ESEEDIANAL KF
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 agccgcagca aattaattta ttttaaattt
-070 tcccgtcaaa gagttatttc ataaatcaat accgcaatat ttaaattgcg gtttttaagg gtatttttct
0001 atgagtaatg ttattgcatc gcttgaaaag gtactcctcc cttttgcagt taaaatagga aagcagccac
0071 acgttaatgc aatcaaaaat ggctttattc gcttaatgcc gttaaccctt gcgggggcca tgtttgtatt
0141 aattaacaac gtttttctaa gctttgggga ggggtcgttt ttttattcct taggtattcg cctcgacgcc
0211 tcaaccattg aaacacttaa tggtctgaaa ggtattggcg gcaacgtata taacggaaca ttaggaataa
0281 tgtctttaat ggcaccgttc tttattggca tggcgctggc agaagagcgt aaagtcgatg cgctggcggc
0351 tgggttgtta tccgttgcag catttatgac cgtcacccca tatagtgtcg gtgaggccta tgcggttggt
0421 gcaaactggt taggtggggc gaatatcatc tccgggatta ttattggcct ggtggtggca gaaatgttta
0491 cctttattgt ccgccgcaat tgggtcatta aactgcccga cagcgtacct gcttcagtat cgcgttcctt
0561 ctcggcatta attcccggct ttattattct ttccgtgatg gggattattg cctgggcgtt gaatacctgg
0631 ggcaccaact tccatcagat cattatggat accatctcaa ccccactggc atcgttgggt agcgtggtgg
0701 gctgggccta tgtgatcttt gttccactgc tctggttctt cggtattcat ggcgcgctgg cgctgaccgc
0771 actggacaac ggcattatga cgccgtgggc actggaaaat atcgcgacct atcagcaata tggttccgtc
0841 gaagcggcgc tggcagccgg taagaccttc catatctggg ccaagccgat gctggactcc tttattttcc
0911 ttgggggcag tggtgcgact ttaggcctga tcctggctat ctttatcgcc tctcgccgtg ctgattatcg
0981 tcaggtggca aaactggcgc tgccgtccgg catcttccag attaacgaac cgattctgtt tggtctgcca
1051 attatcatga acccggtgat gtttatcccg tttgtactgg tacaaccgat tctggcggca atcaccctcg
1121 cagcgtacta catgggcatt attcctccgg tgaccaatat tgcaccgtgg accatgccaa ccggtctggg
1191 agccttcttt aacaccaacg gtagcgtcgc cgcattgctg gtcgcactct tcaaccttgg catcgcaacg
1261 ttaatttatc tgccctttgt tgtggtggct aacaaagcac aaaatgcgat tgataaagaa gagagcgaag
1331 aagatatcgc taacgccctg aaattttaat cgatgccggt acgggtaatc gtgccggtaa gaaaagagag
1401 gaacgatgta tgatggatct cgataacatt cccgatacgc aaacggaagc tgaagagct
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