PEC Original Annotations
|
Essentiality
|
Class
|
non-essential
|
References (PMID)
|
Vaccine. 1992;10(11):766-76.
Genotypic and phenotypic characterization of an aroD deletion-attenuated Escherichia coli K12-Shigella flexneri hybrid vaccine expressing S. flexneri 2a somatic antigen.
Newland JW, Hale TL, Formal SB.
(
1441732
)
|
|
Deletion
|
OCL87
(D)
|
Related gene (W3110 PEC)
|
Gene Search
|
Search MG1655 PEC by gene name:
aroD
|
Related strains
|
Strains Search
|
Search strains by gene name:
aroD
Search strains by all related name:
aroD b1693 ECK1691 JW1683
|
General information (Go to Linear View: )
|
Gene Name
|
aroD
|
Alternative name
|
b1693,ECK1691,JW1683
|
Location, Length
|
1,772,710 - 1,773,468
(
+
)
;
38.21
min
;
759
(bp) ,
252
(aa)
|
Product
|
3-dehydroquinate dehydratase
|
Operon Name
|
ydiNB-aroD
|
Note
|
GO_process: GO:0009423 - chorismate biosynthetic process
|
Function
|
enzyme; Amino acid biosynthesis: Chorismate
|
Gene Ontology
|
GO:0003824;
catalytic activity ( aroD )
GO:0003855;
3-dehydroquinate dehydratase activity ( aroD )
GO:0008152;
metabolic process ( aroD )
GO:0008652;
amino acid biosynthetic process ( aroD )
GO:0009073;
aromatic amino acid family biosynthetic process ( aroD )
GO:0016829;
lyase activity ( aroD )
|
PID
|
1787984
|
EC number
(KEGG Pathway)
|
4.2.1.10
|
Verified Protein Starts
(data
compiled from literature and appropriate citations are available from EcoGene)
|
EcoGene
|
aroD
(
EG10076
)
|
Number of removed
|
0 aa cleaved
|
SWISS-PROT
(
Show details
[
2
more]
)
|
Entry name(Acc.no)
|
AROD_ECOLI
(
P05194
)
|
- Protein name
|
3-dehydroquinate dehydratase
|
- Synonyms
|
EC 4.2.1.10, 3-dehydroquinase, Type I DHQase
|
- Gene name
|
Name=aroD; OrderedLocusNames=b1693;
|
MMBR References
|
Gene. 1981;14(1-2):73-80.
The cloning and analysis of the aroD gene of E. coli K-12.
Kinghorn JR, Schweizer M, Giles NH, Kushner SR.
(
7021325
)
|
J Bacteriol. 1987;169(5):1949-53.
Defective regulation of the phenylalanine biosynthetic operon in mutants of the phenylalanyl-tRNA synthetase operon.
Borg-Olivier SA, Tarlinton D, Brown KD.
(
3032903
)
|
Sequences |
Amino acid
FASTA format
|
0001 MKTVTVKDLV IGTGAPKIIV SLMAKDIASV KSEALAYREA DFDILEWRVD HYADLSNVES VMAAAKILRE
0071 TMPEKPLLFT FRSAKEGGEQ AISTEAYIAL NRAAIDSGLV DMIDLELFTG DDQVKETVAY AHAHDVKVVM
0141 SNHDFHKTPE AEEIIARLRK MQSFDADIPK IALMPQSTSD VLTLLAATLE MQEQYADRPI ITMSMAKTGV
0211 ISRLAGEVFG SAATFGAVKK ASAPGQISVN DLRTVLTILH QA
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 GTTCACATTA TGGACTGGCA AAGATTTCCC
-070 TCTGGAATAT GTTAAACAGG TCATGGGGTT CGGTGCCTGA CAGGCTGACC GCGTGCAGAA AGGGTAAAAA
0001 atgaaaaccg taactgtaaa agatctcgtc attggtacgg gcgcacctaa aatcatcgtc tcgctgatgg
0071 cgaaagatat cgccagcgtg aaatccgaag ctctcgccta tcgtgaagcg gactttgata ttctggaatg
0141 gcgtgtggac cactatgccg acctctccaa tgtggagtct gtcatggcgg cagcaaaaat tctccgtgag
0211 accatgccag aaaaaccgct gctgtttacc ttccgcagtg ccaaagaagg cggcgagcag gcgatttcca
0281 ccgaggctta tattgcactc aatcgtgcag ccatcgacag cggcctggtt gatatgatcg atctggagtt
0351 atttaccggt gatgatcagg ttaaagaaac cgtcgcctac gcccacgcgc atgatgtgaa agtagtcatg
0421 tccaaccatg acttccataa aacgccggaa gccgaagaaa tcattgcccg tctgcgcaaa atgcaatcct
0491 tcgacgccga tattcctaag attgcgctga tgccgcaaag taccagcgat gtgctgacgt tgcttgccgc
0561 gaccctggag atgcaggagc agtatgccga tcgtccaatt atcacgatgt cgatggcaaa aactggcgta
0631 atttctcgtc tggctggtga agtatttggc tcggcggcaa cttttggtgc ggtaaaaaaa gcgtctgcgc
0701 cagggcaaat ctcggtaaat gatttgcgca cggtattaac tattttacac caggcataaG CAATAATATT
0771 TCGGCGGGAA CACCCTCCCC GCCGAACTAA AAAATATATT CAATCGTATT TAATAAAAAT ATTTCGTGAG
0841 TCTCTGTGCG CTAATTCTC
|