MG1655
W3110
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Gene Report : malI
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)  
     Deletion DE(PLK1608)  ,  OCL90-3 (D)  
Related gene (W3110 PEC)
     Gene Search Search MG1655 PEC by gene name:  malI
Related strains
     Strains Search Search strains by gene name:  malI   Search strains by all related name:  malI b1620 ECK1615 f342 JW1612

General information  (Go to Linear View:)
 Gene Name malI  
 Alternative name b1620,ECK1615,f342,JW1612  
 Location, Length 1,696,176 - 1,697,204 (  -  ) ;   36.56 min ; 1029 (bp) ,   342 (aa) Go to Linear View
 Product transcriptional repressor of Mal regulon  
 Operon Name malI  
 Note maltose regulon regulatory protein; GO_component: GO:0005737 - cytoplasm; GO_function: GO:0016564 - transcription repressor activity; GO_process: GO:0016052 - carbohydrate catabolic process; GO_process: GO:0006350 - transcription  
 Function regulator; Degradation of small molecules: Carbon compounds  
 Gene Ontology GO:0003677 ; DNA binding ( malI )
GO:0003700 ; transcription factor activity ( malI )
GO:0005622 ; intracellular ( malI )
GO:0006350 ; transcription ( malI )
GO:0006355 ; regulation of transcription, DNA-dependent ( malI )
 PID 1787906  
 EC number
  (KEGG Pathway)
 
 
SWISS-PROT  ( Show details [ 2 more] )
  botton Entry name(Acc.no) MALI_ECOLI ( P18811 ; P77151 )
    -  Protein name Maltose regulon regulatory protein malI.  
    -  Synonyms  
    -  Gene name Name=malI; OrderedLocusNames=b1620;  

 Linear View (Whole Mode)
View Location
   1685.0  –  1710.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP malI (  homologous genes of other bacterias  )  
    PDB     (database updated : 2007.02.20 )
         PSI-BLAST Chain A, Purine Repressor Mutant-Hypoxanthine-Purf Operator Complex  
    SWISS-PROT     (database updated : 2007.02.20 )
         BLAST Maltose regulon regulatory protein malI  
         PSI-BLAST HTH-type transcriptional repressor purR
    nr     (database updated : 2007.02.20 )
         BLAST repressor of malXY [Shigella flexneri 2a str. 301]  
Pfam 28.0   (database updated : 2015-05 )
    Pfam
PROSITE
    PROSITE ASN_GLYCOSYLATION    GLYCOSAMINOGLYCAN    CAMP_PHOSPHO_SITE    PKC_PHOSPHO_SITE    CK2_PHOSPHO_SITE    MYRISTYL    HTH_LACI_FAMILY     

Other Cross-Reference
    COG COG1609K 
    EcoCyc malI 

MMBR References
J Bacteriol. 1987;169(8):3539-45.
Identification of endogenous inducers of the mal regulon in Escherichia coli.
Ehrmann M, Boos W. ( 3038842 )
J Bacteriol. 1989;171(9):4888-99.
MalI, a novel protein involved in regulation of the maltose system of Escherichia coli, is highly homologous to the repressor proteins GalR, CytR, and LacI.
Reidl J, Romisch K, Ehrmann M, Boos W. ( 2670898 )

Sequences
Amino acid
FASTA format
0001 MATAKKITIH DVALAAGVSV STVSLVLSGK GRISTATGER VNAAIEELGF VRNRQASALR GGQSGVIGLI 
0071 VRDLSAPFYA ELTAGLTEAL EAQGRMVFLL HGGKDGEQLA QRFSLLLNQG VDGVVIAGAA GSSDDLRRMA 
0141 EEKAIPVIFA SRASYLDDVD TVRPDNMQAA QLLTEHLIRN GHQRIAWLGG QSSSLTRAER VGGYCATLLK 
0211 FGLPFHSDWV LECTSSQKQA AEAITALLRH NPTISAVVCY NETIAMGAWF GLLKAGRQSG ESGVDRYFEQ 
0281 QVSLAAFTDA TPTTLDDIPV TWASTPAREL GITLADRMMQ KITHEETHSR NLIIPARLIA AK

Nucleotide
FASTA format

View sequence out neighbor 100bp
-100                                             gtgaggcata aatcacatta cgcaacgata 
-070 atagcgggta taagataaat aaaaggtaaa acgttttatc tgtcacataa tcagggagta ggtcatctgc 
0001 atggctaccg ccaaaaaaat aaccattcat gatgttgcgc tggctgcggg cgtgtcggta agtaccgttt 
0071 cgctggtgct tagtggcaaa gggcgaatct ctaccgccac aggagaacgc gttaacgccg ccattgaaga 
0141 gctgggattt gtgcgcaatc gccaggcgtc ggcgctgcgc ggcgggcaaa gcggcgtcat tggtttgatc 
0211 gtccgtgatt tatctgcgcc gttttacgcc gaattgacgg ccggattgac ggaagctctg gaagcgcagg 
0281 gacggatggt ttttttgctt cacggcggta aagacggtga gcagctggca cagcggtttt cactgttact 
0351 gaatcagggt gtcgatggtg tggtaattgc cggagctgca ggaagtagcg atgacctgcg acggatggca 
0421 gaagaaaaag ctatcccggt gattttcgct tcccgtgcca gttatcttga tgatgttgat acggttcgcc 
0491 cggacaacat gcaggctgca cagttgttga cggagcatct cattcgcaat gggcatcagc ggatcgcctg 
0561 gctgggaggg caaagttcct cattaacccg tgcagaacgg gttgggggct attgtgcaac tctactaaaa 
0631 tttggcctgc cgtttcatag cgattgggtg ttggagtgca cttccagcca gaagcaagcc gcggaagcta 
0701 tcacggcgct tttacgtcat aacccgacca tcagtgccgt ggtttgctat aacgaaacta ttgcgatggg 
0771 ggcatggttt ggtttgctca aagcagggcg gcaaagcggg gaaagcggag tcgatcgtta ctttgagcaa 
0841 caggtttcgc tggcggcatt taccgatgcg acaccaacca cacttgatga tatacctgtt acctgggcca 
0911 gcacgccagc gcgggaactt ggtatcacac ttgcggatcg catgatgcaa aaaatcaccc atgaagagac 
0981 gcattcacgc aatcttatta ttcccgcccg gctcattgca gcgaaataat cctctcttta tctgctatac 
1051 ctggtagtgt cctttcctca aggttaatga taaaaaatgt ggcacacagg cggtgccttt tatttttact 
1121 gaagttcac