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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
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Deletion
|
20
(LD)
,
DE(PLK1608)
,
OCR70,L90-5 (LD 20-1_P/O)
(D)
,
OCR70,L90-6 (LD 20-1_P/O & 20-2TC)
(D)
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Related gene (W3110 PEC)
|
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Gene Search
|
Search MG1655 PEC by gene name:
ldhA
|
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Related strains
|
|
Strains Search
|
Search strains by gene name:
ldhA
Search strains by all related name:
ldhA b1380 ECK1377 hslF hslI htpH JW1375
|
General information (Go to Linear View: )
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Gene Name
|
ldhA
|
|
Alternative name
|
b1380,ECK1377,hslF,hslI,htpH,JW1375
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Location, Length
|
1,439,878 - 1,440,867
(
-
)
;
31.03
min
;
990
(bp) ,
329
(aa)
|
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Product
|
fermentative D-lactate dehydrogenase, NAD-dependent
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Operon Name
|
ldhA
|
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Note
|
GO_process: GO:0006113 - fermentation
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Function
|
enzyme; Energy metabolism, carbon: Fermentation
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Gene Ontology
|
GO:0003824
;
catalytic activity ( ldhA )
GO:0005488
;
binding ( ldhA )
GO:0005737
;
cytoplasm ( ldhA )
GO:0006950
;
response to stress ( ldhA )
GO:0008152
;
metabolic process ( ldhA )
GO:0008720
;
D-lactate dehydrogenase activity ( ldhA )
GO:0016491
;
oxidoreductase activity ( ldhA )
GO:0016616
;
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor ( ldhA )
GO:0048037
;
cofactor binding ( ldhA )
GO:0051287
;
NAD binding ( ldhA )
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PID
|
1787645
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EC number
(KEGG Pathway)
|
1.1.1.28
|
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SWISS-PROT
(
Show details
[
2
more]
)
|
Entry name(Acc.no)
|
LDHD_ECOLI
(
P52643
;
P78152
)
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- Protein name
|
D-lactate dehydrogenase
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- Synonyms
|
EC 1.1.1.28, D-LDH, Fermentative lactate dehydrogenase
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- Gene name
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Name=ldhA; Synonyms=hslI, htpH; OrderedLocusNames=b1380;
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MMBR References
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J Bacteriol. 1989;171(1):342-8.
Mutants of Escherichia coli deficient in the fermentative lactate dehydrogenase.
Mat-Jan F, Alam KY, Clark DP.
(
2644194
)
|
J Bacteriol. 1993;175:5242-5252
Characterization of twenty-six new heat shock genes of Escherichia coli.
Chuang, S. E., and F. R. Blattner.
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| Sequences |
Amino acid
FASTA format
|
0001 MKLAVYSTKQ YDKKYLQQVN ESFGFELEFF DFLLTEKTAK TANGCEAVCI FVNDDGSRPV LEELKKHGVK
0071 YIALRCAGFN NVDLDAAKEL GLKVVRVPAY DPEAVAEHAI GMMMTLNRRI HRAYQRTRDA NFSLEGLTGF
0141 TMYGKTAGVI GTGKIGVAML RILKGFGMRL LAFDPYPSAA ALELGVEYVD LPTLFSESDV ISLHCPLTPE
0211 NYHLLNEAAF EQMKNGVMIV NTSRGALIDS QAAIEALKNQ KIGSLGMDVY ENERDLFFED KSNDVIQDDV
0281 FRRLSACHNV LFTGHQAFLT AEALTSISQT TLQNLSNLEK GETCPNELV
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 atgaattttt caatatcgcc atagctttca
-070 attaaatttg aaattttgta aaatattttt agtagcttaa atgtgattca acatcactgg agaaagtctt
0001 atgaaactcg ccgtttatag cacaaaacag tacgacaaga agtacctgca acaggtgaac gagtcctttg
0071 gctttgagct ggaatttttt gactttctgc tgacggaaaa aaccgctaaa actgccaatg gctgcgaagc
0141 ggtatgtatt ttcgtaaacg atgacggcag ccgcccggtg ctggaagagc tgaaaaagca cggcgttaaa
0211 tatatcgccc tgcgctgtgc cggtttcaat aacgtcgacc ttgacgcggc aaaagaactg gggctgaaag
0281 tagtccgtgt tccagcctat gatccagagg ccgttgctga acacgccatc ggtatgatga tgacgctgaa
0351 ccgccgtatt caccgcgcgt atcagcgtac ccgtgatgct aacttctctc tggaaggtct gaccggcttt
0421 actatgtatg gcaaaacggc aggcgttatc ggtaccggta aaatcggtgt ggcgatgctg cgcattctga
0491 aaggttttgg tatgcgtctg ctggcgttcg atccgtatcc aagtgcagcg gcgctggaac tcggtgtgga
0561 gtatgtcgat ctgccaaccc tgttctctga atcagacgtt atctctctgc actgcccgct gacaccggaa
0631 aactatcatc tgttgaacga agccgccttc gaacagatga aaaatggcgt gatgatcgtc aataccagtc
0701 gcggtgcatt gattgattct caggcagcaa ttgaagcgct gaaaaatcag aaaattggtt cgttgggtat
0771 ggacgtgtat gagaacgaac gcgatctatt ctttgaagat aaatccaacg acgtgatcca ggatgacgta
0841 ttccgtcgcc tgtctgcctg ccacaacgtg ctgtttaccg ggcaccaggc attcctgaca gcagaagctc
0911 tgaccagtat ttctcagact acgctgcaaa acttaagcaa tctggaaaaa ggcgaaacct gcccgaacga
0981 actggtttaa tcttgccgct cccctgcatt ccaggggagc tgattcagat aatccccaat gacctttcat
1051 cctctattct taaaatagtc ctgagtcaga aactgtaatt
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