MG1655
W3110
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Gene Report : sapD
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
     Deletion 20 (LD)  ,  OCR70 (D)  ,  OCR70,L90-5 (LD 20-1_P/O) (D)  ,  OCR70,L90-6 (LD 20-1_P/O & 20-2TC) (D)  
Related gene (W3110 PEC)
     Gene Search Search MG1655 PEC by gene name:  sapD
Related strains
     Strains Search Search strains by gene name:  sapD   Search strains by all related name:  sapD b1291 ECK1286 f330 JW1284 trkE

General information  (Go to Linear View:)
 Gene Name sapD  
 Alternative name b1291,ECK1286,f330,JW1284,trkE  
 Location, Length 1,350,660 - 1,351,652 (  -  ) ;   29.11 min ; 993 (bp) ,   330 (aa) Go to Linear View
 Product antimicrobial peptide transport ABC system ATP-binding protein  
 Operon Name sapABCDF  
 Note putative ATP-binding protein of peptide transport system; GO_component: GO:0005737 - cytoplasm; GO_process: GO:0009063 - cellular amino acid catabolic process  
 Function putative transport; Not classified  
 Gene Ontology GO:0000166 ; nucleotide binding ( sapD )
GO:0005524 ; ATP binding ( sapD )
GO:0005886 ; plasma membrane ( sapD )
GO:0006810 ; transport ( sapD )
GO:0006857 ; oligopeptide transport ( sapD )
GO:0015031 ; protein transport ( sapD )
GO:0015197 ; peptide transporter activity ( sapD )
GO:0015198 ; oligopeptide transporter activity ( sapD )
GO:0015833 ; peptide transport ( sapD )
GO:0016020 ; membrane ( sapD )
GO:0016887 ; ATPase activity ( sapD )
GO:0017111 ; nucleoside-triphosphatase activity ( sapD )
 PID 1787548  
 EC number
  (KEGG Pathway)
 
 
SWISS-PROT  ( Show details )
  botton Entry name(Acc.no) SAPD_ECOLI ( P36635 )
    -  Protein name Peptide transport system ATP-binding protein sapD.  
    -  Synonyms  
    -  Gene name OrderedLocusNames=b1291, c1768, z2499, ECs1868, SF1296, S1378;  

 Linear View (Whole Mode)
View Location
   1340.0  –  1365.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP sapD (  homologous genes of other bacterias  )  
    PDB     (database updated : 2007.02.20 )
         PSI-BLAST Chain 1, Malk  
    SWISS-PROT     (database updated : 2007.02.20 )
         BLAST Peptide transport system ATP-binding protein sapD  
         PSI-BLAST Methionine import ATP-binding protein metN
    nr     (database updated : 2007.02.20 )
         BLAST putative ATP-binding protein of peptide transport system [Escherichia coli O157:H7 EDL933]  
Pfam 28.0   (database updated : 2015-05 )
    Pfam
PROSITE
    PROSITE ASN_GLYCOSYLATION    GLYCOSAMINOGLYCAN    PKC_PHOSPHO_SITE    CK2_PHOSPHO_SITE    MYRISTYL    ATP_GTP_A     

Other Cross-Reference
    COG COG4170V 
    EcoCyc sapD 

MMBR References
J Bacteriol. 1971;108(2):639-44.
Potassium transport loci in Escherichia coli K-12.
Epstein W, Kim BS. ( 4942756 )
EMBO J. 1993;12:4053-4062
Molecular genetic analysis of a locus required for resistance to antimicrobial peptides in Salmonella typhimurium.
Parra-Lopez, C., M. T. Baer, and E. A. Groisman.
EMBO J. 1994;13:3964-3972
A Salmonella protein that is required for resistance to antimicrobial peptides and transport of potassium.
Parra-Lopez, C., R. Lin, A. Aspedon, and E. A. Groisman.
Mol Microbiol. 1993;9(3):533-43.
NAD+ binding to the Escherichia coli K(+)-uptake protein TrkA and sequence similarity between TrkA and domains of a family of dehydrogenases suggest a role for NAD+ in bacterial transport.
Schlosser A, Hamann A, Bossemeyer D, Schneider E, Bakker EP. ( 8412700 )

Sequences
Amino acid
FASTA format
0001 MPLLDIRNLT IEFKTGDEWV KAVDRVSMTL TEGEIRGLVG ESGSGKSLIA KAICGVNKDN WRVTADRMRF 
0071 DDIDLLRLSA RERRKLVGHN VSMIFQEPQS CLDPSERVGR QLMQNIPAWT YKGRWWQRFG WRKRRAIELL 
0141 HRVGIKDHKD AMRSFPYELT EGECQKVMIA IALANQPRLL IADEPTNSME PTTQAQIFRL LTRLNQNSNT 
0211 TILLISHDLQ MLSQWADKIN VLYCGQTVET APSKELVTMP HHPYTQALIR AIPDFGSAMP HKSRLNTLPG 
0281 AIPLLEQLPI GCRLGPRCPY AQRECIVTPR LTGAKNHLYA CHFPLNMEKE 

Nucleotide
FASTA format

View sequence out neighbor 100bp
-100                                             ggactgtcat gctgccaggt gcggcaatta 
-070 tgattagcgt gttgttggtt aacctccttg gcgatggcgt tcgtcgtgcg attattgcgg gggtggaata 
0001 atgccattac tcgatattcg taacctgacc attgaattta aaaccggtga tgagtgggtt aaagccgtcg 
0071 accgggtaag tatgacctta accgaaggtg aaatccgcgg tcttgttggt gaatccggtt ccggcaagag 
0141 tttgattgcg aaagcgattt gtggggtgaa taaagataac tggcgtgtta ctgctgaccg tatgcgtttt 
0211 gatgatatcg atttgctgcg tctctccgca cgcgaacggc gcaaactggt tggccataac gtgtcgatga 
0281 ttttccagga accgcagtcg tgtcttgacc cttcagaacg tgtgggccgc cagttgatgc aaaacatccc 
0351 agcctggacc tataaaggcc gttggtggca gcgttttggc tggcgcaaac gccgtgccat tgaactgctg 
0421 caccgcgtgg ggattaaaga tcacaaagat gcgatgcgca gttttcccta tgagttgacc gaaggtgaat 
0491 gtcagaaagt gatgatagcc attgcactgg cgaatcaacc gcgtctgctg attgctgacg aaccgaccaa 
0561 ctcaatggag ccaacaaccc aggcgcaaat ctttcgcctg ctgacgcgtc tcaaccaaaa cagcaatacc 
0631 actattttgc ttatcagcca tgacttacaa atgcttagcc aatgggcgga taaaattaac gtgctttact 
0701 gcggtcaaac agtggaaacc gcgccgagta aggagttggt gacgatgcca catcatcctt atacccaggc 
0771 gctgatccgc gcgataccag acttcggcag cgcgatgccg cataaaagtc gcctcaatac gctgcccggc 
0841 gctatcccac tgctggaaca gttaccgatt ggttgtcgtc tggggccacg ttgcccgtat gcacaacgag 
0911 aatgcattgt gacgccacgt ttgacggggg cgaaaaatca tctctatgcc tgtcatttcc cgctgaacat 
0981 ggagaaagag tgagatgatc gaaacgctgc ttgaagtgcg taatttaagt aaaacgttcc gctaccggac 
1051 cggctggttt cgtcgtcaga ccgtagaagc ggtaaaaccc ttg