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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
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Mol Gen Genet. 1989;218(2):361-3.
A locus involved in kanamycin, chloramphenicol and L-serine resistance is located in the bglY-galU region of the Escherichia coli K12 chromosome.
Lejeune P, Bertin P, Walon C, Willemot K, Colson C, Danchin A.
(
2506428
)
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Deletion
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OCR68
(D)
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Related gene (W3110 PEC)
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Gene Search
|
Search MG1655 PEC by gene name:
galU
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Related strains
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Strains Search
|
Search strains by gene name:
galU
Search strains by all related name:
galU b1236 ECK1231 JW1224 verA ychD
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General information (Go to Linear View: )
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Gene Name
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galU
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Alternative name
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b1236,ECK1231,JW1224,verA,ychD
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Location, Length
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1,290,680 - 1,291,588
(
+
)
;
27.82
min
;
909
(bp) ,
302
(aa)
|
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Product
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glucose-1-phosphate uridylyltransferase
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Operon Name
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galU
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Note
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GO_process: GO:0006012 - galactose metabolic process; GO_process: GO:0006006 - glucose metabolic process; GO_process: GO:0009242 - colanic acid biosynthetic process; GO_process: GO:0016052 - carbohydrate catabolic process; GO_process: GO:0009269 - response to desiccation
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Function
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enzyme; Degradation of small molecules: Carbon compounds
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Gene Ontology
|
GO:0000287
;
magnesium ion binding ( galU )
GO:0003983
;
UTP:glucose-1-phosphate uridylyltransferase activity ( galU )
GO:0005515
;
protein binding ( galU )
GO:0006011
;
UDP-glucose metabolic process ( galU )
GO:0009058
;
biosynthetic process ( galU )
GO:0016740
;
transferase activity ( galU )
GO:0016779
;
nucleotidyltransferase activity ( galU )
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PID
|
1787488
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EC number
(KEGG Pathway)
|
2.7.7.9
|
|
Verified Protein Starts
(data
compiled from literature and appropriate citations are available from EcoGene)
|
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EcoGene
|
galU
(
EG11319
)
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Number of removed
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1 aa cleaved
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SWISS-PROT
(
Show details
)
|
Entry name(Acc.no)
|
GALU_ECOLI
(
P25520
)
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- Protein name
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UTP--glucose-1-phosphate uridylyltransferase
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- Synonyms
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EC 2.7.7.9, UDP-glucose pyrophosphorylase, UDPGP, Alpha-D-glucosyl-1-phosphate uridylyltransferase, Uridine diphosphoglucose pyrophosphorylase
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- Gene name
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OrderedLocusNames=b1236, c1700, z2012, ECs1738, SF1236, S1322;
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MMBR References
|
J Bacteriol. 1971;108(3):1210-23.
Resistance of Escherichia coli to penicillins. IX. Genetics and physiology of class II ampicillin-resistant mutants that are galactose negative or sensitive to bacteriophage C21, or both.
Eriksson-Grennberg KR, Nordstrom K, Englund P.
(
4945191
)
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Virology. 1969;38(1):189-91.
Mutation in gal U gene of E. coli blocks phage P1 infection.
Franklin NC.
(
4891220
)
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Mol Gen Genet. 1969;105(4):285-97.
Biochemical and genetic studies with nitrate reductase C-gene mutants of Escherichia coli.
Guest JR.
(
4904136
)
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J Bacteriol. 1966;92(2):518-20.
Chromosomal location of the gene determining uridine diphoglucose formation in Escherichia coli K-12.
Shapiro JA.
(
5330381
)
|
J Virol. 1971;8(5):669-74.
Isolation and characterization of an Escherichia coli bacteriophage requiring cell wall galactose.
Watson G, Paigen K.
(
4943683
)
|
J Bacteriol. 1994;176:2611-2618
UTP:alpha-D-glucose-1-phosphate uridylyltransferase of Escherichia coli: isolation and DNA sequence of the galU gene and purification of the enzyme.
Weissborn, A. C., Q. Liu, M. K. Rumley, and E. P. Kennedy.
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| Sequences |
Amino acid
FASTA format
|
0001 MAAINTKVKK AVIPVAGLGT RMLPATKAIP KEMLPLVDKP LIQYVVNECI AAGITEIVLV THSSKNSIEN
0071 HFDTSFELEA MLEKRVKRQL LDEVQSICPP HVTIMQVRQG LAKGLGHAVL CAHPVVGDEP VAVILPDVIL
0141 DEYESDLSQD NLAEMIRRFD ETGHSQIMVE PVADVTAYGV VDCKGVELAP GESVPMVGVV EKPKADVAPS
0211 NLAIVGRYVL SADIWPLLAK TPPGAGDEIQ LTDAIDMLIE KETVEAYHMK GKSHDCGNKL GYMQAFVEYG
0281 IRHNTLGTEF KAWLEEEMGI KK
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Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 CCTCCTTTTC AGAACTTAGC CCCTTCGGGG
-070 TGCTGATATA CTGGGATGCG ATACAGAAAT ATGAACACGT TCAAAACACG AACAGTCCAG GAGAATTTAA
0001 atggctgcca ttaatacgaa agtcaaaaaa gccgttatcc ccgttgcggg attaggaacc aggatgttgc
0071 cggcgacgaa agccatcccg aaagagatgc tgccacttgt cgataagcca ttaattcaat acgtcgtgaa
0141 tgaatgtatt gcggctggca ttactgaaat tgtgctggtt acacactcat ctaaaaactc tattgaaaac
0211 cactttgata ccagttttga actggaagca atgctggaaa aacgtgtaaa acgtcaactg cttgatgaag
0281 tgcagtctat ttgtccaccg cacgtgacta ttatgcaagt tcgtcagggt ctggcgaaag gcctgggaca
0351 cgcggtattg tgtgctcacc cggtagtggg tgatgaaccg gtagctgtta ttttgcctga tgttattctg
0421 gatgaatatg aatccgattt gtcacaggat aacctggcag agatgatccg ccgctttgat gaaacgggtc
0491 atagccagat catggttgaa ccggttgctg atgtgaccgc atatggcgtt gtggattgca aaggcgttga
0561 attagcgccg ggtgaaagcg taccgatggt tggtgtggta gaaaaaccga aagcggatgt tgcgccgtct
0631 aatctcgcta ttgtgggtcg ttacgtactt agcgcggata tttggccgtt gctggcaaaa acccctccgg
0701 gagctggtga tgaaattcag ctcaccgacg caattgatat gctgatcgaa aaagaaacgg tggaagccta
0771 tcatatgaaa gggaagagcc atgactgcgg taataaatta ggttacatgc aggccttcgt tgaatacggt
0841 attcgtcata acacccttgg cacggaattt aaagcctggc ttgaagaaga gatgggcatt aagaagtaaC
0911 ATCCGTATCG GTGTTATCCA CGAAACGGCG TTGAGCAATC GACGCCGTTT TTTTATAGCT TATTCTTATT
0981 AAATTGTCTT AAACCGGACA ATAAAAAAT
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