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PEC Original Annotations
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Essentiality
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Class
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essential
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References (PMID)
|
EMBO J. 1997;16(23):6947-55.
A novel outer membrane lipoprotein, LolB (HemM), involved in the LolA (p20)-dependent localization of lipoproteins to the outer membrane of Escherichia coli.
Matsuyama S, Yokota N, Tokuda H.
(
9384574
)
|
|
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Deletion
|
OCR67
(D)
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Related gene (W3110 PEC)
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|
Gene Search
|
Search MG1655 PEC by gene name:
lolB
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Related strains
|
|
Strains Search
|
Search strains by gene name:
lolB
Search strains by all related name:
lolB b1209 ECK1197 hemM JW1200 ychC
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General information (Go to Linear View: )
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Gene Name
|
lolB
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Alternative name
|
b1209,ECK1197,hemM,JW1200,ychC
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Location, Length
|
1,262,100 - 1,262,723
(
-
)
;
27.20
min
;
624
(bp) ,
207
(aa)
|
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Product
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lipoprotein localization factor
|
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Operon Name
|
lolB-ispE-prs
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Note
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outer-membrane lipoprotein; GO_component: GO:0009274 - peptidoglycan-based cell wall; GO_component: GO:0009279 - cell outer membrane
|
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Function
|
enzyme; Biosynthesis of cofactors, carriers: Heme, porphyrin
|
|
Gene Ontology
|
GO:0006810
;
transport ( lolB )
GO:0008565
;
protein transporter activity ( lolB )
GO:0009279
;
cell outer membrane ( lolB )
GO:0015031
;
protein transport ( lolB )
GO:0016020
;
membrane ( lolB )
GO:0019867
;
outer membrane ( lolB )
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PID
|
1787460
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EC number
(KEGG Pathway)
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SWISS-PROT
(
Show details
[
2
more]
)
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Entry name(Acc.no)
|
LOLB_ECOLI
(
P61320
;
P24208; Q46753
)
|
|
- Protein name
|
Outer-membrane lipoprotein lolB precursor.
|
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- Synonyms
|
|
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- Gene name
|
Name=lolB; Synonyms=hemM; OrderedLocusNames=b1209;
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Homology Analysis
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BLAST
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|
Bacteria
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GTOP
|
lolB
(
homologous genes of other bacterias
)
|
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PDB
(database updated :
2007.02.20
)
|
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PSI-BLAST
|
Chain A, Crystal Structure Of The Outer Membrane Lipoprotein Receptor, Lolb
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SWISS-PROT
(database updated :
2007.02.20
)
|
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BLAST
|
Outer-membrane lipoprotein lolB precursor
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PSI-BLAST
|
Outer-membrane lipoprotein lolB precursor
|
|
nr
(database updated :
2007.02.20
)
|
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BLAST
|
5-aminolevulinate synthase [Escherichia coli]
|
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Pfam 28.0
(database updated :
2015-05
)
|
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Pfam
|
|
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PROSITE
|
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PROSITE
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PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
TYR_PHOSPHO_SITE
MYRISTYL
PROKAR_LIPOPROTEIN
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MMBR References
|
Gene. 1992;121(1):127-32.
Cloning and characterization of genes involved in the biosynthesis of delta-aminolevulinic acid in Escherichia coli.
Ikemi M, Murakami K, Hashimoto M, Murooka Y.
(
1427085
)
|
J Biol Chem. 1991;266:2542-2548
Two glutamyl-tRNA reductase activities in Escherichia coli.
Jahn, D., and D. Soll.
|
EMBO J. 1997;16:6947-6955
A novel outer membrane lipoprotein, LolB (HemM), involved in the LolA (p20)-dependent localization of lipoproteins to the outer membrane of Escherichia coli.
Matsuyama, S., N. Yokota, and H. Tokuda.
|
EMBO J. 1995;14:3365-3372
A novel periplasmic carrier protein involved in the sorting and transport of Escherichia coli lipoproteins destined for the outer membrane.
Matsuyama, S., T. Tajima, and H. Tokuda.
|
J Bacteriol. 1997;179:4583-4590
Role of the hemA gene product and delta-aminolevulinic acid in regulation of Escherichia coli heme synthesis.
Verderber, E., L. J. Lucast, J. A. Van Dehy, P. Cozart, J. B. Etter, and E. A. Best.
|
J Bacteriol. 1994;176:2743-2746
5-Aminolevulinic acid synthesis in Escherichia coli requires expression of hemA.
Chen, W., C. S. Russell, Y. Murooka, and S. D. Cosloy.
|
| Sequences |
Amino acid
FASTA format
|
0001 MPLPDFRLIR LLPLAALVLT ACSVTTPKGP GKSPDSPQWR QHQQDVRNLN QYQTRGAFAY ISDQQKVYAR
0071 FFWQQTGQDR YRLLLTNPLG STELELNAQP GNVQLVDNKG QRYTADDAEE MIGKLTGMPI PLNSLRQWIL
0141 GLPGDATDYK LDDQYRLSEI TYSQNGKNWK VVYGGYDTKT QPAMPANMEL TDGGQRIKLK MDNWIVK
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 gattctggca attaagacaa cttgaacata
-070 gacgatagcg gacggtaacg ctagcattaa gggttataac tgcaacgtat ctcaaggact tgtcatcact
0001 atgcccctgc ccgattttcg tcttatccgc ctgctaccgc tggctgctct tgtgctcact gcctgttccg
0071 ttaccacgcc caaaggtcct ggcaaaagcc cggattcgcc acaatggcgt cagcatcagc aagacgtgcg
0141 caatcttaat cagtatcaga ctcgcggcgc gttcgcttat atttctgacc aacaaaaagt gtacgcccgc
0211 tttttctggc agcaaaccgg ccaggatcgc taccgtctgc tgctcactaa cccattgggc agcacggaac
0281 tggagctgaa tgctcaaccg ggtaacgtgc agttagtcga caataaaggt cagcgttata ccgccgatga
0351 cgccgaagag atgattggca aattgaccgg aatgccaatt ccgctcaaca gcttgcgcca gtggatttta
0421 ggtttaccgg gtgatgcaac cgactacaaa ctggacgacc agtaccgcct gagcgaaatt acctacagcc
0491 agaatggcaa aaactggaag gttgtttatg gtggttatga caccaaaacg caacctgcga tgccagccaa
0561 tatggaactc accgacggtg gtcaacgcat caagttaaaa atggataact ggatagtgaa ataatgcgga
0631 cacagtggcc ctctccggca aaacttaatc tgtttttata cattaccggt cagcgtgcgg atggttacca
0701 cacgctgcaa acgctgtttc agtt
|
