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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
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J Biol Chem. 1992;267(10):6807-14.
Isolation and characterization of the beta-ketoacyl-acyl carrier protein synthase III gene (fabH) from Escherichia coli K-12.
Tsay JT, Oh W, Larson TJ, Jackowski S, Rock CO.
(
1551888
)
|
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Deletion
|
OCR61,62-3
(D)
,
OCR61,62-4
(D)
|
|
Related gene (W3110 PEC)
|
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Gene Search
|
Search MG1655 PEC by gene name:
fabH
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Related strains
|
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Strains Search
|
Search strains by gene name:
fabH
Search strains by all related name:
fabH b1091 ECK1077 JW1077
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General information (Go to Linear View: )
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Gene Name
|
fabH
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Alternative name
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b1091,ECK1077,JW1077
|
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Location, Length
|
1,147,982 - 1,148,935
(
+
)
;
24.74
min
;
954
(bp) ,
317
(aa)
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Product
|
3-oxoacyl-[acyl-carrier-protein] synthase III
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Operon Name
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yceD-rpmF-plsX-fabHDG-acpP-fabF
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Note
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3-oxoacyl-[acyl-carrier-protein] synthase III; acetylCoA ACP transacylase; GO_component: GO:0005737 - cytoplasm
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Function
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enzyme; Fatty acid and phosphatidic acid biosynthesis
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Gene Ontology
|
GO:0003824
;
catalytic activity ( fabH )
GO:0004315
;
3-oxoacyl-[acyl-carrier-protein] synthase activity ( fabH )
GO:0005737
;
cytoplasm ( fabH )
GO:0006633
;
fatty acid biosynthetic process ( fabH )
GO:0008152
;
metabolic process ( fabH )
GO:0008415
;
acyltransferase activity ( fabH )
GO:0008610
;
lipid biosynthetic process ( fabH )
GO:0016740
;
transferase activity ( fabH )
|
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PID
|
1787333
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EC number
(KEGG Pathway)
|
2.3.1.41
|
|
Verified Protein Starts
(data
compiled from literature and appropriate citations are available from EcoGene)
|
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EcoGene
|
fabH
(
EG10277
)
|
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Number of removed
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0 aa cleaved
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SWISS-PROT
(
Show details
)
|
Entry name(Acc.no)
|
FABH_ECOLI
(
P24249
)
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- Protein name
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3-oxoacyl-[acyl-carrier-protein] synthase III
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- Synonyms
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EC 2.3.1.41, Beta- ketoacyl-ACP synthase III, KAS III, EcFabH
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- Gene name
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Name=fabH; OrderedLocusNames=b1091, c1360, z1730, ECs1469;
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MMBR References
|
J Bacteriol. 1992;174(23):7873-4.
Physical locations of genes in the rne (ams)-rpmF-plsX-fab region of the Escherichia coli K-12 chromosome.
Oh W, Larson TJ.
(
1447160
)
|
Nucleic Acids Res. 1996;24:1747-1752
Identification of promoter and stringent regulation of transcription of the fabH, fabD and fabG genes encoding fatty acid biosynthetic enzymes of Escherichia coli.
Podkovyrov, S. M., and T. J. Larson.
|
J Biol Chem. 1992;267:6807-6814
Isolation and characterization of the beta-ketoacyl-acyl carrier protein synthase III gene (fabH) from Escherichia coli K-12.
Tsay, J. T., W. Oh, T. J. Larson, S. Jackowski, and C. O. Rock.
|
| Sequences |
Amino acid
FASTA format
|
0001 MYTKIIGTGS YLPEQVRTNA DLEKMVDTSD EWIVTRTGIR ERHIAAPNET VSTMGFEAAT RAIEMAGIEK
0071 DQIGLIVVAT TSATHAFPSA ACQIQSMLGI KGCPAFDVAA ACAGFTYALS VADQYVKSGA VKYALVVGSD
0141 VLARTCDPTD RGTIIIFGDG AGAAVLAASE EPGIISTHLH ADGSYGELLT LPNADRVNPE NSIHLTMAGN
0211 EVFKVAVTEL AHIVDETLAA NNLDRSQLDW LVPHQANLRI ISATAKKLGM SMDNVVVTLD RHGNTSAASV
0281 PCALDEAVRD GRIKPGQLVL LEAFGGGFTW GSALVRF
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 CTGGACGGTG GCAAAAGCGG AACTCTGCGG
-070 TAGCAGGACG CTGCCAGCGA ACTCGCAGTT TGCAAGTGAC GGTATATAAC CGAAAAGTGA CTGAGCGTAC
0001 atgtatacga agattattgg tactggcagc tatctgcccg aacaagtgcg gacaaacgcc gatttggaaa
0071 aaatggtgga cacctctgac gagtggattg tcactcgtac cggtatccgc gaacgccaca ttgccgcgcc
0141 aaacgaaacc gtttcaacca tgggctttga agcggcgaca cgcgcaattg agatggcggg cattgagaaa
0211 gaccagattg gcctgatcgt tgtggcaacg acttctgcta cgcacgcttt cccgagcgca gcttgtcaga
0281 ttcaaagcat gttgggcatt aaaggttgcc cggcatttga cgttgcagca gcctgcgcag gtttcaccta
0351 tgcattaagc gtagccgatc aatacgtgaa atctggggcg gtgaagtatg ctctggtcgt cggttccgat
0421 gtactggcgc gcacctgcga tccaaccgat cgtgggacta ttattatttt tggcgatggc gcgggcgctg
0491 cggtgctggc tgcctctgaa gagccgggaa tcatttccac ccatctgcat gccgacggta gttatggtga
0561 attgctgacg ctgccaaacg ccgaccgcgt gaatccagag aattcaattc atctgacgat ggcgggcaac
0631 gaagtcttca aggttgcggt aacggaactg gcgcacatcg ttgatgagac gctggcggcg aataatcttg
0701 accgttctca actggactgg ctggttccgc atcaggctaa cctgcgtatt atcagtgcaa cggcgaaaaa
0771 actcggtatg tctatggata atgtcgtggt gacgctggat cgccacggta atacctctgc ggcctctgtc
0841 ccgtgcgcgc tggatgaagc tgtacgcgac gggcgcatta agccggggca gttggttctg cttgaagcct
0911 ttggcggtgg attcacctgg ggctccgcgc tggttcgttt ctagGATAAG GATTAAAACA TGACGCAATT
0981 TGCATTTGTG TTCCCTGGAC AGGGTTCTCA AACCGTTGGA ATGCTGGCTG ATATGGCGGC GAGCTATCCA
1051 ATTG
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