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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
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Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
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Deletion
|
OCL06
(D)
,
LD3-12-1
(LD)
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Related gene (W3110 PEC)
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Gene Search
|
Search MG1655 PEC by gene name:
uhpA
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Related strains
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Strains Search
|
Search strains by gene name:
uhpA
Search strains by all related name:
uhpA b3669 ECK3660 f196 JW3644
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General information (Go to Linear View: )
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Gene Name
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uhpA
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Alternative name
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b3669,ECK3660,f196,JW3644
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Location, Length
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3,848,159 - 3,848,749
(
-
)
;
82.94
min
;
591
(bp) ,
196
(aa)
|
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Product
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DNA-binding response regulator in two-component regulatory system wtih UhpB
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Operon Name
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ivbL-ilvBN-uhpABC
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Note
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response regulator, positive activator of uhpT transcription (sensor, uhpB); GO_component: GO:0005737 - cytoplasm; GO_function: GO:0016563 - transcription activator activity; GO_process: GO:0016052 - carbohydrate catabolic process; GO_process: GO:0006350 - transcription
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Function
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regulator; Transport of small molecules: Carbohydrates, organic acids, alcohols
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Gene Ontology
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GO:0000156
;
two-component response regulator activity ( uhpA )
GO:0000160
;
two-component signal transduction system (phosphorelay) ( uhpA )
GO:0003677
;
DNA binding ( uhpA )
GO:0003700
;
transcription factor activity ( uhpA )
GO:0005351
;
sugar:hydrogen ion symporter activity ( uhpA )
GO:0005515
;
protein binding ( uhpA )
GO:0005622
;
intracellular ( uhpA )
GO:0005737
;
cytoplasm ( uhpA )
GO:0006350
;
transcription ( uhpA )
GO:0006355
;
regulation of transcription, DNA-dependent ( uhpA )
GO:0006810
;
transport ( uhpA )
GO:0008643
;
carbohydrate transport ( uhpA )
GO:0043565
;
sequence-specific DNA binding ( uhpA )
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PID
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1790102
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EC number
(KEGG Pathway)
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Verified Protein Starts
(data
compiled from literature and appropriate citations are available from EcoGene)
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EcoGene
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uhpA
(
EG11051
)
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Number of removed
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0 aa cleaved
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SWISS-PROT
(
Show details
)
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Entry name(Acc.no)
|
UHPA_ECOLI
(
P10940
)
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- Protein name
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Transcriptional regulatory protein uhpA.
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- Synonyms
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- Gene name
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OrderedLocusNames=b3669, c4593, z5159, ECs4606, SF3792, S3976;
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MMBR References
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J Bacteriol. 1987;169(8):3556-63.
Nucleotide sequence of the uhp region of Escherichia coli.
Friedrich MJ, Kadner RJ.
(
3301805
)
|
J Bacteriol. 1992;174:2754-2762
Structure and function of the uhp genes for the sugar phosphate transport system in Escherichia coli and Salmonella typhimurium.
Island, M. D., B. Y. Wei, and R. J. Kadner.
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J Bacteriol. 1983;155(3):1052-61.
Genetic control of the hexose phosphate transport system of Escherichia coli: mapping of deletion and insertion mutations in the uhp region.
Kadner RJ, Shattuck-Eidens DM.
(
6309737
)
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J Bacteriol. 1983;155(3):1062-70.
Molecular cloning of the uhp region and evidence for a positive activator for expression of the hexose phosphate transport system of Escherichia coli.
Shattuck-Eidens DM, Kadner RJ.
(
6350260
)
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J Bacteriol. 1987;169(8):3546-55.
Identification of uhp polypeptides and evidence for their role in exogenous induction of the sugar phosphate transport system of Escherichia coli K-12.
Weston LA, Kadner RJ.
(
3038843
)
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| Sequences |
Amino acid
FASTA format
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0001 MITVALIDDH LIVRSGFAQL LGLEPDLQVV AEFGSGREAL AGLPGRGVQV CICDISMPDI SGLELLSQLP
0071 KGMATIMLSV HDSPALVEQA LNAGARGFLS KRCSPDELIA AVHTVATGGC YLTPDIAIKL ASGRQDPLTK
0141 RERQVAEKLA QGMAVKEIAA ELGLSPKTVH VHRANLMEKL GVSNDVELAR RMFDGW
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Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 caagatcgcg gtgttttttc agtaaccgct
-070 caaggcttga acaacatcgc gcttatcgtt aaggtaagcg cgtatttttt ttacccgcca ggacaagacc
0001 atgatcaccg ttgcccttat agacgatcac ctcatcgtcc gctccggctt tgcgcagctg ctggggctgg
0071 aacctgattt gcaggtagtt gccgagtttg gttcggggcg cgaggcgctg gcggggctgc cggggcgcgg
0141 tgtgcaggtg tgtatttgcg atatctccat gcccgatatc tccggtctgg agctgctaag ccagctgccg
0211 aaaggtatgg cgacgattat gctctccgtt cacgacagtc ctgcgctggt tgagcaggcg cttaacgcgg
0281 gggcacgcgg ctttctttcc aaacgctgta gcccggatga actcattgct gcggtgcata cggttgccac
0351 gggcggctgt tatctgacgc cggatattgc cattaaactg gcatccggtc gtcaggaccc gctaaccaaa
0421 cgtgaacgcc aggtggcgga aaaactggcg caaggaatgg cggtgaaaga gattgccgcc gaactgggct
0491 tgtcaccgaa aacggtacac gtccatcgcg ccaatctgat ggaaaaactg ggcgtcagta acgacgtaga
0561 gctggcgcgc cgcatgtttg atggctggtg atgaagacgt tgttctcccg cttaattacc gttattgcct
0631 gcttttttat cttctctgcc gcatggtttt gcctgtggag tatcagcctg catctggttg a
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