MG1655
W3110
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Gene Report : dkgB
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)  
     Deletion OCR36 (D)  
Related gene (W3110 PEC)
     Gene Search Search MG1655 PEC by gene name:  dkgB
Related strains
     Strains Search Search strains by gene name:  dkgB   Search strains by all related name:  dkgB b0207 ECK0207 JW0197 yafB

General information  (Go to Linear View:)
 Gene Name dkgB  
 Alternative name b0207,ECK0207,JW0197,yafB  
 Location, Length 229,167 - 229,970 (  +  ) ;   4.94 min ; 804 (bp) ,   267 (aa) Go to Linear View
 Product 2,5-diketo-D-gluconate reductase B  
 Operon Name dkgB  
 Note GO_component: GO:0005737 - cytoplasm; GO_process: GO:0016052 - carbohydrate catabolic process  
 Function putative enzyme; Not classified  
 Gene Ontology GO:0005515 ; protein binding ( dkgB )
GO:0005737 ; cytoplasm ( dkgB )
GO:0016491 ; oxidoreductase activity ( dkgB )
GO:0019853 ; L-ascorbic acid biosynthetic process ( dkgB )
GO:0050580 ; 2,5-didehydrogluconate reductase activity ( dkgB )
 PID 1786400  
 EC number
  (KEGG Pathway)   		1.1.1.274  
SWISS-PROT  ( Show details [ 1 more] )
  botton Entry name(Acc.no) DKGB_ECOLI ( P30863 ; P77777 )
    -  Protein name 2,5-diketo-D-gluconic acid reductase B  
    -  Synonyms EC 1.1.1.274, 2,5-DKG reductase B, 2,5-DKGR B, 25DKGR-B, AKR5D  
    -  Gene name Name=dkgB; OrderedLocusNames=b0207;  

 Linear View (Whole Mode)
View Location
   220.0  –  245.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP dkgB (  homologous genes of other bacterias  )  
    PDB     (database updated : 2007.02.20 )
         PSI-BLAST Chain A, Crystal Structure Of Rabbit 20alpha Hyroxysteroid Dehydrogenase In Ternary Complex With Nadp And Testosterone  
    SWISS-PROT     (database updated : 2007.02.20 )
         BLAST 2,5-diketo-D-gluconic acid reductase B  
         PSI-BLAST Aldo-keto reductase family 1 member C1 homolog
    nr     (database updated : 2007.02.20 )
         BLAST 2,5-diketo-D-gluconate reductase B [Escherichia coli K12]  
Pfam 28.0   (database updated : 2015-05 )
    Pfam
PROSITE
    PROSITE ASN_GLYCOSYLATION    PKC_PHOSPHO_SITE    CK2_PHOSPHO_SITE    MYRISTYL    ALDOKETO_REDUCTASE_2    ALDOKETO_REDUCTASE_1     

Other Cross-Reference
    COG COG0656R 
    EcoCyc dkgB 

Sequences
Amino acid
FASTA format 
0001 MAIPAFGLGT FRLKDDVVIS SVITALELGY RAIDTAQIYD NEAAVGQAIA ESGVPRHELY ITTKIWIENL 
0071 SKDKLIPSLK ESLQKLRTDY VDLTLIHWPS PNDEVSVEEF MQALLEAKKQ GLTREIGISN FTIPLMEKAI 
0141 AAVGAENIAT NQIELSPYLQ NRKVVAWAKQ HGIHITSYMT LAYGKALKDE VIARIAAKHN ATPAQVILAW 
0211 AMGEGYSVIP SSTKRKNLES NLKAQNLQLD AEDKKAIAAL DCNDRLVSPE GLAPEWD
Nucleotide
FASTA format

View sequence out neighbor 100bp 
-100                                             AGAATCGCAA AAATCCTCTG CATTTTACGC 
-070 TCTTTTTCCT CAACAGTCTG AAGCCCATAA TCACCTCAGT TAACGAAAAT AGCATTAAAA GAGGCATATT 
0001 atggctatcc ctgcatttgg tttaggtact ttccgtctga aagacgacgt tgttatttca tctgtgataa 
0071 cggcgcttga acttggttat cgcgcaattg ataccgcaca aatctatgat aacgaagccg cagtaggtca 
0141 ggcgattgca gaaagtggcg tgccacgtca tgaactctac atcaccacta aaatctggat tgaaaatctc 
0211 agcaaagaca aattgatccc aagtctgaaa gagagcctgc aaaaattgcg taccgattat gttgatctga 
0281 cgctaatcca ctggccgtca ccaaacgatg aagtctctgt tgaagagttt atgcaggcgc tgctggaagc 
0351 caaaaaacaa gggctgacgc gtgagatcgg tatttccaac ttcacgatcc cgttgatgga aaaagcgatt 
0421 gctgctgttg gtgctgaaaa catcgctact aaccagattg aactctctcc ttatctgcaa aaccgtaaag 
0491 tggttgcctg ggctaaacag cacggcatcc atattacttc ctatatgacg ctggcgtatg gtaaggccct 
0561 gaaagatgag gttattgctc gtatcgcagc taaacacaat gcgactccgg cacaagtgat tctggcgtgg 
0631 gctatggggg aaggttactc agtaattcct tcttctacta aacgtaaaaa cctggaaagt aatcttaagg 
0701 cacaaaattt acagcttgat gccgaagata aaaaagcgat cgccgcactg gattgcaacg accgcctggt 
0771 tagcccggaa ggtctggctc ctgaatggga ttaaGCCTCT CTGACAGCTC CTCCGGGAGC TGTTTTTACA 
0841 TGCTCGCTAA GGAAATCGAT AAAAGCCCGG ATGCGCGTAC TTACCGCACG GTCGCTGTAA TAGA