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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
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Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
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Deletion
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OCR10,11-11 (AK1-16 / BK2-16)
(D)
,
OCR10,11-16 (BK5-16 / AK7-16)
(D)
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Related gene (W3110 PEC)
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Gene Search
|
Search MG1655 PEC by gene name:
rplA
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Related strains
|
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Strains Search
|
Search strains by gene name:
rplA
Search strains by all related name:
rplA b3984 ECK3975 JW3947 rpy
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General information (Go to Linear View: )
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Gene Name
|
rplA
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Alternative name
|
b3984,ECK3975,JW3947,rpy
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Location, Length
|
4,176,902 - 4,177,606
(
+
)
;
90.03
min
;
705
(bp) ,
234
(aa)
|
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Product
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50S ribosomal subunit protein L1
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Operon Name
|
rplKAJL-rpoBC
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Note
|
50S ribosomal subunit protein L1, regulates synthesis of L1 and L11; GO_component: GO:0005737 - cytoplasm; GO_function: GO:0003735 - structural constituent of ribosome; GO_process: GO:0006412 - translation; GO_process: GO:0009386 - translational attenuation
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Function
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structural component; Ribosomal proteins - synthesis, modification
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Gene Ontology
|
GO:0000049
;
tRNA binding ( rplA )
GO:0003723
;
RNA binding ( rplA )
GO:0003735
;
structural constituent of ribosome ( rplA )
GO:0005515
;
protein binding ( rplA )
GO:0005622
;
intracellular ( rplA )
GO:0005840
;
ribosome ( rplA )
GO:0006412
;
translation ( rplA )
GO:0006417
;
regulation of translation ( rplA )
GO:0015934
;
large ribosomal subunit ( rplA )
GO:0019843
;
rRNA binding ( rplA )
GO:0030529
;
ribonucleoprotein complex ( rplA )
|
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PID
|
1790416
|
EC number
(KEGG Pathway)
|
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Verified Protein Starts
(data
compiled from literature and appropriate citations are available from EcoGene)
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EcoGene
|
rplA
(
EG10864
)
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Number of removed
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1 aa cleaved
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SWISS-PROT
(
Show details
)
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Entry name(Acc.no)
|
RL1_ECOLI
(
P02384
)
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- Protein name
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50S ribosomal protein L1.
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- Synonyms
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- Gene name
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Name=rplA; OrderedLocusNames=b3984, c4940, z5557, ECs4907;
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Homology Analysis
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BLAST
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Bacteria
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GTOP
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rplA
(
homologous genes of other bacterias
)
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PDB
(database updated :
2007.02.20
)
|
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PSI-BLAST
|
Chain N, Fitting Of Components With Known Structure Into An 11.5 A Cryo-Em Map Of The E.Coli 70s Ribosome
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SWISS-PROT
(database updated :
2007.02.20
)
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BLAST
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50S ribosomal protein L1
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PSI-BLAST
|
50S ribosomal protein L1
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nr
(database updated :
2007.02.20
)
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BLAST
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50S ribosomal protein L1 [Escherichia coli O157:H7 EDL933]
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Pfam 28.0
(database updated :
2015-05
)
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Pfam
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PROSITE
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PROSITE
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CAMP_PHOSPHO_SITE
PKC_PHOSPHO_SITE
MYRISTYL
RIBOSOMAL_L1
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MMBR References
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J Mol Biol. 1987;194(4):609-20.
Transcription products from the rplKAJL-rpoBC gene cluster.
Downing WL, Dennis PP.
(
2443706
)
|
J Bacteriol. 1982;152(3):1022-32.
Insertions of transposon Tn5 into ribosomal protein PNA polymerase operons.
Hui I, Maltman K, Little R, Hastrup S, Johnsen M, Fiil N, Dennis P.
(
6292159
)
|
J Bacteriol. 1979;140(2):479-89.
Lambda transducing bacteriophage carrying deletions of the argCBH-rpoBC region of the Escherichia coli chromosome.
Linn T, Goman M, Scaife J.
(
159290
)
|
J Bacteriol. 1981;147(1):25-35.
Transcriptional and post-transcriptional control of ribosomal protein and ribonucleic acid polymerase genes.
Little R, Fiil NP, Dennis PP.
(
7016843
)
|
Mol Gen Genet. 1981;184(3):548-50.
Internal promoters of the rpoBC operon of Escherichia coli.
Ma JC, Newman AJ, Hayward RS.
(
6278264
)
|
Proc Natl Acad Sci U S A. 1979;76:1697-1701
Nucleotide sequence of the ribosomal protein gene cluster adjacent to the gene for RNA polymerase subunit beta in Escherichia coli.
Post, L. E., G. D. Strycharz, M. Nomura, H. Lewis, and P. P. Dennis.
|
J Bacteriol. 1984;158(1):279-85.
Relative activities of the transcriptional regulatory sites in the rplKAJLrpoBC gene cluster of Escherichia coli.
Ralling G, Linn T.
(
6325390
)
|
Mol Gen Genet. 1981;183(2):277-82.
In vivo synthesis of a polycistronic messenger RNA for the ribosomal proteins L11, L1, L10 and L7/12 in Escherichia coli.
Bruckner R, Matzura H.
(
7035827
)
|
J Bacteriol. 1980;144(3):904-16.
Characterization of promoter-cloning plasmids: analysis of operon structure in the rif region of Escherichia coli and isolation of an enhanced internal promoter mutant.
An G, Friesen JD.
(
7002914
)
|
| Sequences |
Amino acid
FASTA format
|
0001 MAKLTKRMRV IREKVDATKQ YDINEAIALL KELATAKFVE SVDVAVNLGI DARKSDQNVR GATVLPHGTG
0071 RSVRVAVFTQ GANAEAAKAA GAELVGMEDL ADQIKKGEMN FDVVIASPDA MRVVGQLGQV LGPRGLMPNP
0141 KVGTVTPNVA EAVKNAKAGQ VRYRNDKNGI IHTTIGKVDF DADKLKENLE ALLVALKKAK PTQAKGVYIK
0211 KVSISTTMGA GVAVDQAGLS ASVN
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 GACCAAAGCT GCCGACATGA CTGGTGCCGA
-070 CATTGAAGCG ATGACTCGCT CCATCGAAGG TACTGCACGT TCCATGGGCC TGGTAGTGGA GGACTAAGAA
0001 atggctaaac tgaccaagcg catgcgtgtt atccgcgaga aagttgatgc aaccaaacag tacgacatca
0071 acgaagctat cgcactgctg aaagagctgg cgactgctaa attcgtagaa agcgtggacg tagctgttaa
0141 cctcggcatc gacgctcgta aatctgacca gaacgtacgt ggtgcaactg tactgccgca cggtactggc
0211 cgttccgttc gcgtagccgt atttacccaa ggtgcaaacg ctgaagctgc taaagctgca ggcgcagaac
0281 tggtaggtat ggaagatctg gctgaccaga tcaagaaagg cgaaatgaac tttgacgttg ttattgcttc
0351 tccggatgca atgcgcgttg ttggccagct gggccaggtt ctgggtccgc gcggcctgat gccaaacccg
0421 aaagtgggta ctgtaacacc gaacgttgct gaagcggtta aaaacgctaa agctggccag gttcgttacc
0491 gtaacgacaa aaacggcatc atccacacca ccatcggtaa agtggacttt gacgctgaca aactgaaaga
0561 aaacctggaa gctctgctgg ttgcgctgaa aaaagcaaaa ccgactcagg cgaaaggcgt gtacatcaag
0631 aaagttagca tctccaccac catgggtgca ggtgttgcag ttgaccaggc tggcctgagc gcttctgtaa
0701 actaaTGCCT TTACGTGGGC GGTGATTTTG TCTACAATCT TACCCCCACG TATAATGCTT AATGCAGACG
0771 TATATCCGAG ATATTCGGGT TGTGGCAAGG CGGCA
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