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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
|
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
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Deletion
|
OCL07
(D)
|
|
Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
recG
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Related strains
|
|
Strains Search
|
Search strains by gene name:
recG
Search strains by all related name:
recG b3652 ECK3642 JW3627 o693 radC spoV
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General information (Go to Linear View: )
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Gene Name
|
recG
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Alternative name
|
b3652,ECK3642,JW3627,o693,radC,spoV
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Location, Length
|
3,823,233 - 3,825,314
(
+
)
;
82.40
min
;
2082
(bp) ,
693
(aa)
|
|
Product
|
ATP-dependent DNA helicase
|
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Operon Name
|
rpoZ-spoT-trmH-recG
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Note
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DNA helicase, resolution of Holliday junctions, branch migration; GO_component: GO:0005737 - cytoplasm; GO_process: GO:0006261 - DNA-dependent DNA replication
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Function
|
enzyme; DNA - replication, repair,restriction/modification
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Gene Ontology
|
GO:0000166
;
nucleotide binding ( recG )
GO:0003676
;
nucleic acid binding ( recG )
GO:0003677
;
DNA binding ( recG )
GO:0004003
;
ATP-dependent DNA helicase activity ( recG )
GO:0004386
;
helicase activity ( recG )
GO:0005515
;
protein binding ( recG )
GO:0005524
;
ATP binding ( recG )
GO:0006281
;
DNA repair ( radC )
GO:0006281
;
DNA repair ( recG )
GO:0006310
;
DNA recombination ( recG )
GO:0006974
;
response to DNA damage stimulus ( radC )
GO:0006974
;
response to DNA damage stimulus ( recG )
GO:0008026
;
ATP-dependent helicase activity ( recG )
GO:0016787
;
hydrolase activity ( recG )
|
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PID
|
2367254
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EC number
(KEGG Pathway)
|
3.6.1.-
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SWISS-PROT
(
Show details
[
2
more]
)
|
Entry name(Acc.no)
|
RECG_ECOLI
(
P24230
;
P76721
)
|
|
- Protein name
|
ATP-dependent DNA helicase recG
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- Synonyms
|
EC 3.6.1.-
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- Gene name
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Name=recG; OrderedLocusNames=b3652;
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Homology Analysis
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BLAST
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Bacteria
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GTOP
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recG
(
homologous genes of other bacterias
)
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PDB
(database updated :
2007.02.20
)
|
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PSI-BLAST
|
Chain A, Structure Of Recg Bound To Three-Way Dna Junction
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SWISS-PROT
(database updated :
2007.02.20
)
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BLAST
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ATP-dependent DNA helicase recG
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PSI-BLAST
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UvrABC system protein B
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nr
(database updated :
2007.02.20
)
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BLAST
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ATP-dependent DNA helicase [Escherichia coli K12]
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Pfam 28.0
(database updated :
2015-05
)
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Pfam
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PROSITE
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PROSITE
|
ASN_GLYCOSYLATION
CAMP_PHOSPHO_SITE
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
TYR_PHOSPHO_SITE
MYRISTYL
AMIDATION
ATP_GTP_A
LEUCINE_ZIPPER
PEROXIDASE_1
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MMBR References
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Genetics 1996;142:25-37
Two enzymes, both of which process recombination intermediates, have opposite effects on adaptive mutation in Escherichia coli.
Foster, P. L., J. M. Trimarchi, and R. A. Maurer.
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Gene. 1992;110(1):95-9.
The nucleotide sequence of recG, the distal spo operon gene in Escherichia coli K-12.
Kalman M, Murphy H, Cashel M.
(
1544582
)
|
J Bacteriol. 1991;173(17):5414-8.
Conjugational recombination in resolvase-deficient ruvC mutants of Escherichia coli K-12 depends on recG.
Lloyd RG.
(
1653210
)
|
J Bacteriol. 1991;173(3):1004-11.
Genetic analysis of the recG locus of Escherichia coli K-12 and of its role in recombination and DNA repair.
Lloyd RG, Buckman C.
(
1846849
)
|
J Bacteriol. 1991;173(21):6837-43.
Molecular organization and nucleotide sequence of the recG locus of Escherichia coli K-12.
Lloyd RG, Sharples GJ.
(
1938888
)
|
EMBO J. 1993;12:17-22
Dissociation of synthetic Holliday junctions by E. coli RecG protein.
Lloyd, R. G., and G. J. Sharples.
|
Nucleic Acids Res. 1993;21:1719-1725
Processing of recombination intermediates by the RecG and RuvAB proteins of Escherichia coli.
Lloyd, R. G., and G. J. Sharples.
|
Mutat Res. 1994;311(1):103-9.
Ruv and recG genes and the induced precise excision of Tn10 in Escherichia coli.
Nagel R, Chan A, Rosen E.
(
7526163
)
|
EMBO J. 1994;13:5220-5228
Branch migration of Holliday junctions: identification of RecG protein as a junction specific DNA helicase.
Whitby, M. C., S. D. Vincent, and R. G. Lloyd.
|
J Bacteriol. 1996;178:6782-6789
Modulation of recombination and DNA repair by the RecG and PriA helicases of Escherichia coli K-12.
Al-Deib, A. A., A. A. Mahdi, and R. G. Lloyd.
|
| Sequences |
Amino acid
FASTA format
|
0001 MKGRLLDAVP LSSLTGVGAA LSNKLAKINL HTVQDLLLHL PLRYEDRTHL YPIGELLPGV YATVEGEVLN
0071 CNISFGGRRM MTCQISDGSG ILTMRFFNFS AAMKNSLAAG RRVLAYGEAK RGKYGAEMIH PEYRVQGDLS
0141 TPELQETLTP VYPTTEGVKQ ATLRKLTDQA LDLLDTCAIE ELLPPELSQG MMTLPEALRT LHRPPPTLQL
0211 SDLETGQHPA QRRLILEELL AHNLSMLALR AGAQRFHAQP LSANDTLKNK LLAALPFKPT GAQARVVAEI
0281 ERDMALDVPM MRLVQGDVGS GKTLVAALAA LRAIAHGKQV ALMAPTELLA EQHANNFRNW FAPLGIEVGW
0351 LAGKQKGKAR LAQQEAIASG QVQMIVGTHA IFQEQVQFNG LALVIIDEQH RFGVHQRLAL WEKGQQQGFH
0421 PHQLIMTATP IPRTLAMTAY ADLDTSVIDE LPPGRTPVTT VAIPDTRRTD IIDRVHHACI TEGRQAYWVC
0491 TLIEESELLE AQAAEATWEE LKLALPELNV GLVHGRMKPA EKQAVMASFK QGELHLLVAT TVIEVGVDVP
0561 NASLMIIENP ERLGLAQLHQ LRGRVGRGAV ASHCVLLYKT PLSKTAQIRL QVLRDSNDGF VIAQKDLEIR
0631 GPGELLGTRQ TGNAEFKVAD LLRDQAMIPE VQRLARHIHE RYPQQAKALI ERWMPETERY SNA
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 CAAAACGCAA AGGCCTGCCT TATCCCCACG
-070 TCAATCAGCA AGGCGAGATC GAAGCTGATG CCGACTGGTG GGCTACTATG CAGGCTGCAG GGTAAGTGCC
0001 atgaaaggtc gcctgttaga tgctgtccca ctcagttccc taacgggcgt tggcgcagca cttagtaaca
0071 aactggcgaa aatcaacctg cataccgtgc aggatctact cttacacctt cccctgcgct acgaagatcg
0141 cacccatctc taccccatcg gagaactact gccgggcgtt tatgccacgg tggaaggcga agtgctgaac
0211 tgcaatatct ccttcggcgg tcggcggatg atgacctgcc agatcagcga cggttccggc atcctcacca
0281 tgcgcttttt caatttcagc gcggcaatga aaaatagcct ggcggcgggc cgccgtgtac tggcttatgg
0351 cgaagcaaag cgcggtaaat atggtgcgga gatgatccac ccggaatacc gcgtgcaggg cgatctcagc
0421 acgccagaat tacaggaaac gctcacgccg gtttatccaa caacggaagg cgtaaagcag gccacgctgc
0491 gtaaattaac cgaccaggcg ctggatctgc tcgacacctg cgccattgaa gaactcctgc cgccggaact
0561 gtcacaagga atgatgacgc taccggaagc gttgcgcact ttgcaccgcc cgccaccgac gctacagctt
0631 agcgatctgg aaaccgggca gcatccggcg caacgtcgtc tgattctgga agaactgctg gcgcacaacc
0701 tcagcatgtt agccttacgt gccggagcac agcgttttca tgcccagccg ctgagcgcca atgacacgct
0771 gaaaaataaa ctcctcgccg ccttaccgtt caagccaacg ggcgcacagg cacgcgtagt ggcggagatc
0841 gagcgcgata tggcgctgga tgtgccgatg atgcgtctgg tgcagggcga tgtaggttcc ggtaaaacgc
0911 tggtcgccgc cctcgccgcg ttgcgtgcga ttgcccacgg caaacaggta gcattgatgg caccaaccga
0981 attactcgcc gagcagcacg ccaataactt ccgcaactgg tttgcaccgc tcggtatcga agtgggctgg
1051 ctcgccggta agcagaaagg taaagcacgg ctggcacagc aggaagccat cgccagcggt caggtgcaga
1121 tgattgtcgg tacacacgcc atcttccagg aacaggtgca gtttaacggc ctggcgctgg tgattatcga
1191 cgaacagcat cgttttggcg tgcatcagcg tctggcattg tgggagaaag gccagcagca gggcttccat
1261 ccgcatcagt tgatcatgac cgccacgccg atcccccgca cgctggcaat gactgcgtat gccgatctcg
1331 atacctcggt gatagatgag ctgccgccag gccgcacgcc agtgactacg gtcgctattc ctgatacccg
1401 ccgtaccgac atcattgacc gcgtgcacca cgcctgcata actgaaggtc gtcaggcata ctgggtttgt
1471 acgttgattg aagagtcgga attgctggaa gcgcaggcgg cggaagctac ctgggaagag ttgaaactgg
1541 cgctaccaga gttgaacgtt ggcctggtac acgggcggat gaaacctgcc gagaaacagg cggtgatggc
1611 gtcgtttaaa caaggtgagc tacacctgct ggttgccaca accgttattg aagtcggcgt tgatgtgcct
1681 aacgccagtc tgatgattat cgaaaacccg gagcgtctgg gtctggcgca gttacaccag ctgcgcgggc
1751 gcgtaggtcg tggcgcggtg gcttctcact gcgtgctgct ctacaaaacg ccgctttcta aaacggcgca
1821 aattcgcctg caagtgctgc gcgacagtaa cgacggtttt gtgattgcgc aaaaagatct ggagattcgc
1891 ggccctggcg aattgttagg cacgcgtcag acgggtaatg ctgaatttaa agtggcggat ttactgcgcg
1961 atcaggcgat gatcccggaa gttcagcgcc tggcacgcca tattcacgaa cgttacccac aacaggcaaa
2031 agccctgata gaacgctgga tgccggagac ggaacgttac tcgaatgcgt aaAAGGCGGC AGTGAGAAGA
2101 CCGCCATTTC AGGTTACCCT ACCTTCCTGC CGGATGCGAT TCATCACCCT ACAAATTCAA TAAATTATGA
2171 ATCAATACGC AG
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