|
PEC Original Annotations
|
|
Essentiality
|
|
Class
|
non-essential
|
|
References (PMID)
|
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
|
|
|
Deletion
|
OCL41,42-1
(D)
|
|
Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
recJ
|
|
Related strains
|
|
Strains Search
|
Search strains by gene name:
recJ
Search strains by all related name:
recJ b2892 ECK2887 JW2860
|
General information (Go to Linear View: )
|
|
Gene Name
|
recJ
|
|
Alternative name
|
b2892,ECK2887,JW2860
|
|
Location, Length
|
3,034,395 - 3,036,128
(
-
)
;
65.40
min
;
1734
(bp) ,
577
(aa)
|
|
Product
|
ssDNA exonuclease, 5' --> 3'-specific
|
|
Operon Name
|
xerD-dsbC-recJ-prfB-lysS
|
|
Note
|
ssDNA exonuclease, 5' --> 3' specific; GO_process: GO:0006308 - DNA catabolic process
|
|
Function
|
enzyme; Degradation of DNA
|
|
Gene Ontology
|
GO:0003676
;
nucleic acid binding ( recJ )
GO:0004518
;
nuclease activity ( recJ )
GO:0004527
;
exonuclease activity ( recJ )
GO:0005515
;
protein binding ( recJ )
GO:0006281
;
DNA repair ( recJ )
GO:0006310
;
DNA recombination ( recJ )
GO:0008409
;
5'-3' exonuclease activity ( recJ )
GO:0016787
;
hydrolase activity ( recJ )
GO:0030145
;
manganese ion binding ( recJ )
|
|
PID
|
1789259
|
EC number
(KEGG Pathway)
|
3.1.-.-
|
|
SWISS-PROT
(
Show details
[
2
more]
)
|
Entry name(Acc.no)
|
RECJ_ECOLI
(
P21893
;
Q46823
)
|
|
- Protein name
|
Single-stranded-DNA-specific exonuclease recJ
|
|
- Synonyms
|
EC 3.1.-.-
|
|
- Gene name
|
Name=recJ; OrderedLocusNames=b2892;
|
|
Homology Analysis
|
|
BLAST
|
|
Bacteria
|
|
GTOP
|
recJ
(
homologous genes of other bacterias
)
|
|
PDB
(database updated :
2007.02.20
)
|
|
PSI-BLAST
|
Chain A, Crystal Structure Of Exonuclease Recj Bound To Manganese
|
|
SWISS-PROT
(database updated :
2007.02.20
)
|
|
BLAST
|
Single-stranded-DNA-specific exonuclease recJ
|
|
PSI-BLAST
|
Single-stranded-DNA-specific exonuclease recJ
|
|
nr
(database updated :
2007.02.20
)
|
|
BLAST
|
ssDNA exonuclease, 5' --
|
|
Pfam 28.0
(database updated :
2015-05
)
|
|
Pfam
|
|
|
PROSITE
|
|
PROSITE
|
ASN_GLYCOSYLATION
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
TYR_PHOSPHO_SITE
MYRISTYL
|
|
MMBR References
|
J Bacteriol. 1984;157(1):190-6.
Genetic analysis of the recJ gene of Escherichia coli K-12.
Lovett ST, Clark AJ.
(
6317649
)
|
J Bacteriol. 1985;162(1):280-5.
Cloning of the Escherichia coli recJ chromosomal region and identification of its encoded proteins.
Lovett ST, Clark AJ.
(
2984175
)
|
Proc Natl Acad Sci U S A. 1989;86:2627-2631
Identification and purification of a single-stranded-DNA-specific exonuclease encoded by the recJ gene of Escherichia coli.
Lovett, S. T., and R. D. Kolodner.
|
J Bacteriol. 1991;173(1):353-64.
Nucleotide sequence of the Escherichia coli recJ chromosomal region and construction of recJ-overexpression plasmids.
Lovett ST, Kolodner RD.
(
1987126
)
|
Genetics 1995;140:27-45
Suppression of recJ exonuclease mutants of Escherichia coli by alterations in DNA helicases II (uvrD) and IV (helD).
Lovett, S. T., and V. A. Sutera.
|
J Bacteriol. 1996;178:2362-2367
Role of the recJ gene product in UV-induced illegitimate recombination at the hotspot.
Ukita, T., and H. Ikeda.
|
Biochimie. 1991;73(4):523-32.
rec genes and homologous recombination proteins in Escherichia coli.
Clark AJ.
(
1911953
)
|
| Sequences |
Amino acid
FASTA format
|
0001 MKQQIQLRRR EVDETADLPA ELPPLLRRLY ASRGVRSAQE LERSVKGMLP WQQLSGVEKA VEILYNAFRE
0071 GTRIIVVGDF DADGATSTAL SVLAMRSLGC SNIDYLVPNR FEDGYGLSPE VVDQAHARGA QLIVTVDNGI
0141 SSHAGVEHAR SLGIPVIVTD HHLPGDTLPA AEAIINPNLR DCNFPSKSLA GVGVAFYLML ALRTFLRDQG
0211 WFDERNIAIP NLAELLDLVA LGTVADVVPL DANNRILTWQ GMSRIRAGKC RPGIKALLEV ANRDAQKLAA
0281 SDLGFALGPR LNAAGRLDDM SVGVALLLCD NIGEARVLAN ELDALNQTRK EIEQGMQIEA LTLCEKLERS
0351 RDTLPGGLAM YHPEWHQGVV GILASRIKER FHRPVIAFAP AGDGTLKGSG RSIQGLHMRD ALERLDTLYP
0421 GMMLKFGGHA MAAGLSLEED KFKLFQQRFG ELVTEWLDPS LLQGEVVSDG PLSPAEMTME VAQLLRDAGP
0491 WGQMFPEPLF DGHFRLLQQR LVGERHLKVM VEPVGGGPLL DGIAFNVDTA LWPDNGVREV QLAYKLDINE
0561 FRGNRSLQII IDNIWPI
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 tgctgagcaa tggcacactt gttccgggtt
-070 accagccgcc gaaagagatg aaagaattcc tcgacgaaca ccaaaaaatg accagcggta aataattcgc
0001 gtgaaacaac agatacaact tcgtcgccgt gaagtcgatg aaacggcaga cttgcccgct gaattgcctc
0071 ccttgctgcg ccgtttatac gccagccggg gagtacgcag tgcgcaagaa ctggaacgca gtgttaaagg
0141 tatgctgccc tggcagcaac tgagcggcgt cgaaaaggcc gttgagatcc tttacaacgc ttttcgcgaa
0211 ggaacgcgga ttattgtggt cggtgatttc gacgccgacg gcgcgaccag cacggctcta agcgtgctgg
0281 cgatgcgctc gcttggttgc agcaatatcg actacctggt accaaaccgt ttcgaagacg gttacggctt
0351 aagcccggaa gtggtcgatc aggcccatgc ccgtggcgcg cagttaattg tcacggtgga taacggtatt
0421 tcctcccatg cgggggttga gcacgctcgc tcgttgggca tcccggttat tgttaccgat caccatttgc
0491 caggcgacac attacccgca gcggaagcga tcattaaccc taacttgcgc gactgtaatt tcccgtcgaa
0561 atcactggca ggcgtgggtg tggcgtttta tctgatgctg gcgctgcgca cctttttgcg cgatcagggc
0631 tggtttgatg agcgtaacat cgcaattcct aacctggcag aactgctgga tctggtcgcg ctggggacag
0701 tggcggacgt cgtgccgctg gacgctaata atcgcattct gacctggcag gggatgagtc gcatccgagc
0771 cggaaagtgc cgtccgggga ttaaagcgct gcttgaagtg gcaaaccgtg atgcacaaaa actcgccgcc
0841 agcgatttag gttttgcgct ggggccacgt ctcaatgctg ccggacgact ggacgatatg tccgtcggtg
0911 tggcgctgtt gttgtgcgac aacatcggcg aagcgcgcgt gctggcaaat gaactcgatg cgctaaacca
0981 gacgcgaaaa gagatcgaac aaggaatgca aattgaagcc ctgaccctgt gcgagaaact ggagcgcagc
1051 cgtgacacgc tacccggcgg gctggcaatg tatcaccccg aatggcatca gggcgttgtc ggtattctgg
1121 cttcgcgcat caaagagcgt tttcaccgtc cggttatcgc gtttgcgcca gcaggtgacg gtacgctgaa
1191 aggttccggt cgctccattc aggggctgca tatgcgtgat gcgctggagc gattagacac actctaccct
1261 ggcatgatgc tgaagtttgg cggtcatgcg atggcggcgg gtttgtcgct ggaagaggat aaattcaaac
1331 tctttcaaca acggtttggc gaactggtta ctgagtggct ggacccttcg ctattgcaag gcgaagtggt
1401 atcagacggt ccgttaagcc cggccgaaat gaccatggaa gtggcgcagc tgctgcgcga tgctggcccg
1471 tgggggcaga tgttcccgga gccgctgttt gacggtcatt tccgtctgct gcaacagcgg ctggtgggcg
1541 aacgtcattt gaaggtgatg gtcgaaccgg tcggcggcgg tccactgctg gatggtattg cttttaatgt
1611 cgataccgcc ctctggccgg ataacggcgt gcgcgaagtg caactggctt ataagctcga tatcaacgag
1681 tttcgcggca accgcagcct gcaaattatc atcgacaata tctggccaat ttagcgtcat cttctctata
1751 aaaaagagcg tggattgggt acaatcccgc tcttatcacc gcattttgac tagctcaata aaagaaatca
1821 gaccatgttt gaaa
|
