MG1655
W3110
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Gene Report : rpsL
PEC Original Annotations
Essentiality
     Class essential
     References (PMID)
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
     Deletion OCL22-6 (D)  
Related gene (W3110 PEC)
     Gene Search Search MG1655 PEC by gene name:  rpsL
Related strains
     Strains Search Search strains by gene name:  rpsL   Search strains by all related name:  rpsL asuB b3342 ECK3329 f124 JW3304 strA

General information  (Go to Linear View:)
 Gene Name rpsL  
 Alternative name asuB,b3342,ECK3329,f124,JW3304,strA  
 Location, Length 3,472,200 - 3,472,574 (  -  ) ;   74.84 min ; 375 (bp) ,   124 (aa) Go to Linear View
 Product 30S ribosomal subunit protein S12  
 Operon Name rpsLG-fusA-tufA  
 Note GO_component: GO:0005737 - cytoplasm; GO_function: GO:0003735 - structural constituent of ribosome; GO_process: GO:0006412 - translation  
 Function structural component; Ribosomal proteins - synthesis, modification  
 Gene Ontology GO:0000049 ; tRNA binding ( rpsL )
GO:0003723 ; RNA binding ( rpsL )
GO:0003735 ; structural constituent of ribosome ( rpsL )
GO:0005622 ; intracellular ( rpsL )
GO:0005840 ; ribosome ( rpsL )
GO:0006412 ; translation ( rpsL )
GO:0015935 ; small ribosomal subunit ( rpsL )
GO:0019843 ; rRNA binding ( rpsL )
GO:0030529 ; ribonucleoprotein complex ( rpsL )
GO:0046677 ; response to antibiotic ( rpsL )
 PID 1789740  
 EC number
  (KEGG Pathway)   		 
Verified Protein Starts (data compiled from literature and appropriate citations are available from EcoGene)
     EcoGene rpsL ( EG10911 )  
    Number of removed 1 aa cleaved  
SWISS-PROT  ( Show details )
  botton Entry name(Acc.no) RS12_ECOLI ( P02367 ; Q9F5N3 )
    -  Protein name 30S ribosomal protein S12.  
    -  Synonyms  
    -  Gene name t4057, SF3360, S4402;  

 Linear View (Whole Mode)
View Location
   3460.0  –  3485.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP rpsL (  homologous genes of other bacterias  )  
    PDB     (database updated : 2007.02.20 )
         PSI-BLAST Chain L, Crystal Structure Of The Bacterial Ribosome From Escherichia Coli In Complex With The Antibiotic Kasugamyin At 3.5a Resolution. This File Contains The 30s Subunit Of One 70s Ribosome. The Entire Crystal Structure Contains Two 70s Ribosomes And Is  
    SWISS-PROT     (database updated : 2007.02.20 )
         BLAST 30S ribosomal protein S12  
         PSI-BLAST 30S ribosomal protein S12
    nr     (database updated : 2007.02.20 )
         BLAST 30S ribosomal protein S12 [Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67]  
Pfam 28.0   (database updated : 2015-05 )
    Pfam
PROSITE
    PROSITE PKC_PHOSPHO_SITE    MYRISTYL    RIBOSOMAL_S12     

Other Cross-Reference
    EcoCyc rpsL 

MMBR References
J Biol Chem. 1980;255:4660-4666
DNA sequences from the str operon of Escherichia coli.
Post, L., and M. Nomura.
Genetics 1970;65:9-25
Genetic analysis of streptomycin resistance in Escherichia coli.
Breckenridge, L., and Gorini.

Sequences
Amino acid
FASTA format 
0001 MATVNQLVRK PRARKVAKSN VPALEACPQK RGVCTRVYTT TPKKPNSALR KVCRVRLTNG FEVTSYIGGE 
0071 GHNLQEHSVI LIRGGRVKDL PGVRYHTVRG ALDCSGVKDR KQARSKYGVK RPKA
Nucleotide
FASTA format

View sequence out neighbor 100bp 
-100                                             acaccttttc ggcatcgccc taaaattcgg 
-070 cgtcctcata ttgtgtgagg acgttttatt acgtgtttac gaagcaaaag ctaaaaccag gagctattta 
0001 atggcaacag ttaaccagct ggtacgcaaa ccacgtgctc gcaaagttgc gaaaagcaac gtgcctgcgc 
0071 tggaagcatg cccgcaaaaa cgtggcgtat gtactcgtgt atatactacc actcctaaaa aaccgaactc 
0141 cgcgctgcgt aaagtatgcc gtgttcgtct gactaacggt ttcgaagtga cttcctacat cggtggtgaa 
0211 ggtcacaacc tgcaggagca ctccgtgatc ctgatccgtg gcggtcgtgt taaagacctc ccgggtgttc 
0281 gttaccacac cgtacgtggt gcgcttgact gctccggcgt taaagaccgt aagcaggctc gttccaagta 
0351 tggcgtgaag cgtcctaagg cttaatggtt ctccgttaag taaggccaaa cgttttaact taaatgtcaa 
0421 actaaactcg tagagttttg gacaatcctg aattaacaac ggagtatttc catgc