|
PEC Original Annotations
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|
Essentiality
|
|
Class
|
non-essential
|
|
References (PMID)
|
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
|
|
|
Deletion
|
OCR28
(D)
|
|
Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
caiD
|
|
Related strains
|
|
Strains Search
|
Search strains by gene name:
caiD
Search strains by all related name:
caiD b0036 ECK0037 JW0035 yaaL
|
General information (Go to Linear View: )
|
|
Gene Name
|
caiD
|
|
Alternative name
|
b0036,ECK0037,JW0035,yaaL
|
|
Location, Length
|
35,377 - 36,162
(
-
)
;
0.76
min
;
786
(bp) ,
261
(aa)
|
|
Product
|
carnitinyl-CoA dehydratase
|
|
Operon Name
|
caiTABCDE
|
|
Note
|
carnitine racemase; GO_process: GO:0009310 - amine catabolic process; GO_process: GO:0042413 - carnitine catabolic process
|
|
Function
|
enzyme; Degradation of small molecules: Amines
|
|
Gene Ontology
|
GO:0003824
;
catalytic activity ( caiD )
GO:0008152
;
metabolic process ( caiD )
GO:0016829
;
lyase activity ( caiD )
GO:0016836
;
hydro-lyase activity ( caiD )
|
|
PID
|
221142681
|
EC number
(KEGG Pathway)
|
4.2.1.-
|
|
SWISS-PROT
(
Show details
[
2
more]
)
|
Entry name(Acc.no)
|
CAID_ECOLI
(
P31551
;
P75623
)
|
|
- Protein name
|
Carnitinyl-CoA dehydratase
|
|
- Synonyms
|
EC 4.2.1.-, Crotonobetainyl-CoA hydratase
|
|
- Gene name
|
Name=caiD; OrderedLocusNames=b0036;
|
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Homology Analysis
|
|
BLAST
|
|
Bacteria
|
|
GTOP
|
caiD
(
homologous genes of other bacterias
)
|
|
PDB
(database updated :
2007.02.20
)
|
|
PSI-BLAST
|
Chain A, Structure Of Enoyl-Coa Hydratase Complexed With The Substrate Dac-Coa
|
|
SWISS-PROT
(database updated :
2007.02.20
)
|
|
BLAST
|
Carnitinyl-CoA dehydratase
|
|
PSI-BLAST
|
Carnitinyl-CoA dehydratase
|
|
nr
(database updated :
2007.02.20
)
|
|
BLAST
|
carnitinyl-CoA dehydratase [Escherichia coli K12]
|
|
Pfam 28.0
(database updated :
2015-05
)
|
|
Pfam
|
|
|
PROSITE
|
|
PROSITE
|
ASN_GLYCOSYLATION
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
MYRISTYL
AMIDATION
ENOYL_COA_HYDRATASE
BPD_TRANSP_INN_MEMBR
|
|
MMBR References
|
Mol Microbiol. 1994;13(5):775-86.
Molecular characterization of the cai operon necessary for carnitine metabolism in Escherichia coli.
Eichler K, Bourgis F, Buchet A, Kleber HP, Mandrand-Berthelot MA.
(
7815937
)
|
J Bacteriol. 1998;180:2599-2608
Regulation of the carnitine pathway in Escherichia coli: investigation of the cai-fix divergent promoter region.
Buchet, A., K. Eichler, and M. A. Mandrand-Berthelot.
|
| Sequences |
Amino acid
FASTA format
|
0001 MSESLHLTRN GSILEITLDR PKANAIDAKT SFEMGEVFLN FRDDPQLRVA IITGAGEKFF SAGWDLKAAA
0071 EGEAPDADFG PGGFAGLTEI FNLDKPVIAA VNGYAFGGGF ELALAADFIV CADNASFALP EAKLGIVPDS
0141 GGVLRLPKIL PPAIVNEMVM TGRRMGAEEA LRWGIVNRVV SQAELMDNAR ELAQQLVNSA PLAIAALKEI
0211 YRTTSEMPVE EAYRYIRSGV LKHYPSVLHS EDAIEGPLAF AEKRDPVWKG R
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 gcagggaact accctgccag ctaataatca
-070 cactctaaaa caatatgcat tttttgcagg gatgttgtcg tccctgaaaa agcaaaaatg gagaaaagga
0001 atgagtgaat cattacatct gacccgcaat ggatcaattc tggaaattac ccttgatcgt ccaaaagcga
0071 atgctattga tgcaaaaacc agctttgaaa tgggcgaagt atttctaaat ttccgtgacg atccgcaatt
0141 acgtgtcgcc attattaccg gtgccggaga gaagttcttt tccgcgggct gggatttaaa agcggcagca
0211 gaaggcgaag caccggatgc tgactttggt ccgggtggtt ttgcgggatt aaccgaaatt ttcaatctcg
0281 acaaaccggt tatcgcagct gtgaacggct atgcctttgg cggcggcttt gaactggcgc tggcggcaga
0351 ttttattgtt tgtgccgata acgccagctt cgccctgccg gaagccaaac tgggcatcgt tcctgacagc
0421 ggcggtgtgc tgcgtctgcc gaagatcctg ccgcctgcca tcgtcaatga aatggtgatg accggcagac
0491 gaatgggcgc agaagaggcg ctgcgttggg ggatagtcaa ccgcgtggtt agccaggcgg aactgatgga
0561 taacgcccgc gaactggctc agcagctggt taacagcgcc ccgctggcga ttgcggcgct gaaagagatc
0631 taccgcacca ccagcgaaat gccggtagaa gaagcgtatc gctatattcg cagcggcgtg ttgaaacact
0701 atccatcggt tctgcattcg gaagatgcca ttgaagggcc gctggcgttt gccgagaagc gcgatccggt
0771 gtggaaagga cgttaacaac cgtgagctat tacgcctttg aggggttaat tccggtggtt cacccgacgg
0841 cgtttgtcca tcccagtgcc gtcttgattg gcgatgtgat tgtggg
|
